Biography
Dr. Fassihi has authored or coauthored more than 140 peer-reviewed professional papers on topics related to the relationship between the physicochemical characteristics of drugs, their stability and biological effects. He has trained many professional Pharm.D. and M.S. graduate students. He has mentored 28 Ph.D. students as well as visiting scholars and postdoctoral fellows addressing the core principles of pharmaceutics and biopharmaceutics in drug product development, drug performance, drug therapy, dissolution issues, extended release systems and regulatory requirements etc. He currently teaches, does research, and acts as a consultant to the pharmaceutical industry and government agencies. He has served as an expert witness on issues
related to drug formulations, dissolution characteristics, modified release systems, tampered resistant systems, and bioavailability and bioequivalence issues. He received the B. Pharm. (honors) (1974) Punjab University and Ph.D. (1978) from Brighton University in England, was awarded with a gold medal for his research work.
Courses Taught
Number | Name | Level |
|---|---|---|
PS 8125 | Journ Club/Pharmacodynam | Graduate |
QARA 8007 | Applied Biopharmaceutics | Graduate |
Selected Publications
Recent
Zhang, Q., Durig, T., Blass, B., & Fassihi, R. (2022). Development of an amorphous based sustained release system for apremilast a selective phosphodiesterase 4 (PDE4) inhibitor. Int J Pharm, 615, 121516. Netherlands. 10.1016/j.ijpharm.2022.121516
El-Say, K.M., Ahmed, T.A., Aljefri, A.H., El-Sawy, H.S., Fassihi, R., & Abou-Gharbia, M. (2021). Oleic acid-reinforced PEGylated polymethacrylate transdermal film with enhanced antidyslipidemic activity and bioavailability of atorvastatin: A mechanistic ex-vivo/in-vivo analysis. Int J Pharm, 608, 121057. Netherlands. 10.1016/j.ijpharm.2021.121057
Alshahrouri, B., Yang, F., Schwing, Q., Dürig, T., & Fassihi, R. (2021). Hot-melt extrusion based sustained release ibrutinib delivery system: An inhibitor of Bruton's Tyrosine Kinase (BTK). Int J Pharm, 607, 120981. Netherlands. 10.1016/j.ijpharm.2021.120981