Biography
Dr. Marc A. Ilies is a Professor in the Department of Pharmaceutical
Sciences of Temple University School of Pharmacy in Philadelphia, USA.
His research interests lie in the broadly defined area of bio-organic &
medicinal chemistry/chemical biology at membrane interfaces, where he
combines heterocyclic chemistry and drug design, materials sciences and
pharmaceutical sciences to generate novel therapeutic entities with a high
therapeutic index. Dr. Ilies is particularly interested in pyridinium
derivatives, their synthesis, physicochemical and biological properties,
with a focus on their use in drug and gene delivery systems and towards the
generation of novel biomarkers and theranostic systems. Towards supramolecular chemistry, materials sciences, and nanotechnology his group is
active towards synthesis, self-assembling, physicochemical and biological
properties of assemblies of amphiphilic molecules of different molecular weights and packing parameters
(surfactants, gemini surfactants, lipophilic oligomeric surfactants, lipids, dendrons, polymers) and in their
interfacial engineering for controlling the above-mentioned properties, drug and gene loading and
delivery, enzymatic degradation and toxicity. Other interests include tumor biochemistry and impact of
hypoxia in tumor development and invasiveness.
Dr. Ilies authored more than 75 publications, which have been cited over 2750 times, with an H index of
27. He teaches graduate-level courses in Biochemistry, Medicinal Chemistry and Advanced Drug and
Gene Delivery Systems and he is a member of the editorial board of four peer-reviewed journals on these
topics. Dr. Ilies chaired several sessions dedicated to different aspects related with the use of selfassembled systems in drug and nucleic acid delivery systems within the ACS Division of Colloid and
Surface Chemistry. Besides ACS, he is an active member of AAPS, AACP, ASGCT and Rho Chi Honor
Society. Dr. Ilies is also a Collaborating Member of the Temple Fox Chase Cancer Center, Molecular
Therapeutics Program.
Courses Taught
Number | Name | Level |
---|---|---|
PS 8131 | Principles of Biochemistry | Graduate |
PS 8584 | Advanced Drug and Gene Delivery Systems | Graduate |