P151. Medicinal Chemistry I (4 s.h.) F.

An introductory course in biochemical principles and metabolic pathways with particular emphasis on pharmaceutical applications and biotechnology.

P152. Medicinal Chemistry II (3 s.h.) S.

The chemical basis for drug therapy; molecular mechanisms of drug action; the chemical basis of side effects, toxicities, and drug interactions; and the chemical modification of pharmacokinetic parameters.

P155. Principles of Infectious Disease/Immunology (4 s.h.) F.

Introduction to the infectious process, biotechnology, and laboratory techniques followed by extensive discussion of the immune process and immunology as well as immunological products. The processes involved in disease caused by pathogenic bacteria, viruses, fungi, and parasites will be discussed in detail.

P157. Anatomy/Physiology (5 s.h.) F.

Anatomical considerations with discussion of physiologic aspects of various organ systems.

P158. Anti-Infective Agents (2 s.h.) S.

Will emphasize the pharmacology of antimicrobial classes and their use in the management of infectious diseases.

P161. Pharmaceutics I (3 s.h.) F.

This course covers the format of prescriptions and the organization and contents of monographs and their appendices, the application of mathematics to the preparation of prescriptions and drug products, The design, preparation, properties, and evaluation of solution dosage including incompatibilities and pertinent physical and chemical principles involving solubility and pH effects. Selection of excipients (e.g, color, flavor, buffers, preservatives) and their effect on the performance and quality of these dosage forms is also examined.

P162. Pharmaceutics II (4 s.h.) S.

This course is a continuation of Pharmacy I. It continues with solution dosage forms-colligative properties, and isotonic calculations, ophthalmic, nasal, and optic solutions. Drug degradation and the effect of packaging materials is also examined. The design, preparation, properties, and evaluation of the following additional dosage forms: semisolids (ointments, creams, and suppositories) and dispersions (emulsions, lotions, suspensions, and aerosols) and the selection of excipients, especially surfactants, and their effect on the performance and quality of these dosage forms; chemical incompatibilities among drugs and excipients is covered.

P164. Pharmacology I (4 s.h.) S.

An introductory course in basic pharmacology; terminology, principles, pharmacodynamics, toxicology, and therapeutic aspects of clinically important representatives from the major drug classes. The recitation correlates problem sets with the didactic portion of the course.

P251. Medicinal Chemistry III/Natural Products (3 s.h.) F.

Topics in medicinal chemistry with additional materials incorporated from pharmacognosy.

P261. Pharmaceutics III (4 s.h.) F.

This course covers the design, preparation, properties, and evaluation of solid dosage forms, coating of solid dosage forms, and concepts of prolonged/sustained release products. Drug and formulation factors which affect bioavailability is discussed. Parenteral drug product development, technology, and therapeutic applications are examined as well as excipient selection and its importance to drug product performance and quality for solid and parenteral dosage forms.

P262. Biopharmaceutics and Pharmacokinetics (4 s.h.) S.

An introduction to biopharmaceutics and pharmacokinetics. The course will cover the principles and mechanisms that relate dosage form design to effect therapeutic response, bioavailability, bioequivalence, and drug product selection. An introduction to a quantitative description of the time course of drugs in the body, including absorption, distribution, metabolism, and elimination of drugs and drug-dosage responses is also examined.

P265. Pharmacology II (3 s.h.) F.

A continuation of material from the prior semester.

P310. Psychosocial & Clinical Aspects of Substance Abuse & Addiction (2 s.h.)

Course will educate and sensitize the student to the issue of chemical abuse and dependency. The intention of the course is to give the student a better understanding of the disease and its treatment, help them to recognize clinical signs and symptoms of addiction and supply them with the knowledge as to where to find help.

P381. Emerging Therapeutic Targets (2 s.h.)

An important objective of this team-taught course is to update students on recently approved drugs while exposing them to novel mechanisms being looked at for the development of future drugs. The course is designed to make students aware of a) novel therapeutic targets being considered by the pharmaceutical industry, b) potential new drugs undergoing clinical trails and c) recently approved drugs with novel mechanisms of action. Readings from the basic science and clinical literature will be assigned. Grading will be dependent on written assignments (based on readings); exams and student presentations based on a research project of their choice.

P382. Practical Chromatography (3 s.h.)

Techniques of HPLC and capillary gas chromatography as they apply to the operation of modern computer controlled instrumentation. Emphasis shall be placed on drug related research (medicinal chemistry, pharmacology, and pharmaceutics). A "hands-on" approach including simple laboratory exercises will be employed.

P383. Natural Products (3 s.h.)

The object of the course is to introduce the student to many of the alternative forms of medicine which come from natural sources. When the student has completed this course he/she will be a resource to patients who need information on the safety, efficacy, side effects and drug interactions of various natural products. There will be an emphasis on herbal remedies. Other topics, which will be discussed, include: vitamins, nutrients, homeopathy, enzyme therapy and miscellaneous natural products.

P384. Writing and Publishing a Review Article (2 s.h.)

Students will learn how to successfully approach the dual process involved in writing and publishing a review article in the field of pharmacology and pharmacy. They will work as a team under the guidance of an instructor to identify the type of review article, plan a strategy, allocate tasks, gather library materials (including computer data base searching), write the review article (8-12 pages) and submit for publication.

P387. Veterinary Pharmacy (3 s.h.)

Course will provide the student with the necessary information to develop a specialty in animal health and to be able to advise the client/owner on the care of animals and the use of animal products. Discussions will include the differences between animal families (mammals, reptiles, birds and fish) and their differences in metabolism. Where applicable, species differences with regard to pharmacological effects and drug disposition of medication will be discussed. That a disease can cross over to other species (including humans) will be addressed. Compounding issues concerning animal medications, administration of animal medications and animal models for human research are all topics to be included.

P389. Research (1-3 s.h.)

Three hours of research equal 1 s.h. of credit.