01231/Pharmaceutics
P161. Pharmacy I (3 s.h.)
F. This course covers the format of prescriptions and the organization and contents of monographs and their appendices, the application of mathematics to the preparation of prescriptions and drug products, The design, preparation, properties, and evaluation of solution dosage including incompatibilities and pertinent physical and chemical principles involving solubility and pH effects. Selection of excipients (e.g. color, flavor, buffers, preservatives) and their effect on the performance and quality of these dosage forms is also examined.
P162. Pharmacy II (4 s.h.)
S. This course is a continuation of Pharmacy I. It continues with solution dosage forms - colligative properties, and isotonic calculations, ophthalmic, nasal, and otic solutions. Drug degradation and the effect of packaging materials is also examined. The design, preparation, properties, and evaluation of the following additional dosage forms: semisolids (ointments, creams, and suppositories) and dispersions (emulsions, lotions, suspensions, and aerosols) and the selection of excipients, especially surfactants, and their effect on the performance and quality of these dosage forms; chemical incompatibilities among drugs and excipients is covered.
P261. Pharmacy III (4 s.h.)
F. This course covers the design, preparation, properties, and evaluation of solid dosage forms, coating of solid dosage forms, and concepts of prolonged/sustained release products. Drug and formulation factors which affect bioavailability is discussed. Parenteral drug product development, technology, and therapeutic applications are examined as well as excipient selection and its importance to drug product performance and quality for solid and parenteral dosage forms.
P262. Biopharmaceutics and Pharmacokinetics (4 s.h.)
S. An introduction to biopharmaceutics and pharmacokinetics. The course will cover the principles and mechanisms that relate dosage form design to effect therapeutic response, bioavailability, bioequivalence, and drug product selection. An introduction to a quantitative description of the time course of drugs in the body, including absorption, distribution, metabolism, and elimination of drugs and drug-dosage responses is also examined. |