Michael R. Borenstein, Ph.D.,
Associate Dean.
Synthesis and evaluation of novel pharmacologic agents especially
with regard to the structural prerequisites for anticonvulsant and CNS
activity; development of analytical methodologies (GC/MS and HPLC) for
therapeutic drug monitoring, pharmacokinetics, drug metabolism, and dosage
forms.
michael.borenstein@temple.edu
Daniel J. Canney, Ph.D., Associate
Professor of Medicinal Chemistry and Director of the Office of Graduate
Studies. Design, synthesis and biological evaluation (structure-activity
studies) of novel ligands for cholinergic (muscarinic and nicotinic)
and retinoic acid receptor subtypes; development of synthetic strategies
for the synthesis of organotin precursors of radioiodinated compounds for
use in radioligand binding, autoradiography, and SPECT imaging studies.
daniel.canney@temple.edu
Reza A. Fassihi, Ph.D., Professor
of Biopharmaceutics and Industrial Pharmacy. Drug product design,
formulation and development of conventional and modified drug dosage
forms, intrinsic permeability of the intestinal wall and drug transport,
biopharmaceutical aspects of medicine, in vitro and in vivo evaluation of
pharmaceuticals.
reza.fassihi@temple.edu
Evgeny Krynetskiy, Ph.D.
Associate Professor of Pharmaceutical Sciences. Research focused
on characterization of genetic variability in drug-metabolizing enzymes
and drug transporter reduced folate carrier (RFC). In particular,
development of a genotyping assay of the polymorphic enzyme thiopurine
methyltransferase (TPMT) resulted in improved therapy regimens involving
thiopurines (US patent issued).
Swati Nagar, Ph.D., Assistant
Professor of Pharmaceutical Sciences.
Research concerned with studying the changes in pharmacokinetics which
occur as a result of diseases including sickle cell anemia and various
cancers. In addition, she studies the differences in drug metabolism
attributed pharmacogenetic variability.
James M. Gallo, Pharm.D, Ph.D.,
Professor, University of Arizona
james.gallo@temple.edu
Robert B. Raffa, Ph.D., Professor
of Pharmacology. In vivo evaluation of opioid and nonopioid
peptide and nonpeptide analgesics, mechanisms, tolerance, and
dependence; isolated tissue preparations; theoretical
pharmacology; synergistic drug interactions; thermodynamics of the
drug-receptor interaction.
robert.raffa@temple.edu
Scott M. Rawls, Ph.D., Assistant
Professor of Pharmacodynamics, East Carolina University School of
Medicine, Pharmacology of the opioid, cannabinoid and glutamate systems
using microdialysis techniques. Studies of nociception and pain.
scott.rawls@temple.edu
Tully J. Speaker, Ph.D., Professor of
Pharmacy and Toxicology. Analytical toxicology, drug metabolism,
chromatography theory, percutaneous absorption, microencapsulation.
tully.speaker@temple.edu
Ellen A. Walker, Ph.D., Associate
Professor of Pharmacodynamics, University of Michigan: Behavioral
pharmacology of agents acting at opioid and serotonin receptor systems.
Theoretical aspects of inverse agonists at the 5-HT receptor.
ellen.walker@temple.edu
Albert I. Wertheimer, Ph.D., M.B.A.,
Professor of Pharmacy Practice and Director of Center for
Pharmaceutical Services Research And Pharmacoeconomics.
albert.wertheimer@temple.edu