Peer-reviewed Articles in Past Few Years

Wong HL, Chattopadhyay N, Wu XY, Bendayan R, Nanotechnology applications for improved delivery of antiretrovirals (ARVs) to the brain in HIV Infection, Adv. Drug Deliv. Rev. (in press)

Chattopadhyay N, Zastre J, Wong HL, Wu XY, Bendayan R, Solid Lipid Nanoparticles enhance the delivery of the HIV protease inhibitor, Atazanavir, By a human brain endothelial cell line, Pharm. Res., 25:2262-2271, 2008

Li Y, Wong HL, Shuhendler A, Rauth AM, Wu XY. Molecular interactions,
internal structure and drug release kinetics of rationally developed polymer-lipid hybrid nanoparticles (PLN). J. Control. Release, 128:60-70, 2008.

Wong HL, Bendayan R, Rauth AM, Li Y, Wu XY. Chemotherapy with anticancer drugs entrapped into solid lipid nanoparticles. Adv. Drug Deliv. Rev. 59:491-504, 2007.

Wong HL, Rauth AM, Bendayan R, Wu XY. Evaluation of the in vivo efficacy, toxicity and lymphatic drainage of loco-regional administered polymer-lipid hybrid nanoparticles (PLN) loaded with doxorubicin in a murine solid tumor model. Eur. J. Pharm. Biopharm. 65(3):300-308, 2007. (received Best Paper Awards 2007 from EJPB),

Wong HL, Bendayan R, Rauth AM, Xue HY, Babakhanian K, Wu XY. A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle (PLN) system. J. Pharmacol. Exp. Ther. 317:1372-1381, 2006.

Wong HL, Rauth AM, Bendayan R, Wu XY. Combinational treatment with doxorubicin and GG918 (Elacridar) using polymer-lipid hybrid nanoparticles (PLN) and evaluation of strategies for multidrug-resistance reversal in human breast cancer cells. J. Control. Release 116:275-284, 2006.

Wong HL, Rauth AM, Bendayan R, Manias JL, Ramaswamy M, Liu Z, Erhan SZ, Wu XY. A new polymer-lipid hybrid nanoparticle system increases cytotoxicity of doxorubicin against multidrug resistant human breast cancer cells. Pharm. Res. 23(7):1574-1585, 2006.

Liu J, Wong HL, Moselhy J, Bowen B, Wu XY, Johnston M. Targeting colloidal particulates to thoracic lymph nodes. Lung Cancer 51:377-386, 2006.

Book Chapters

Wong HL, Wu XY, Bendayan R. Multidrug resistance and its reversal, in: Muhato RI, Lu Y (Eds). Pharmaceutical Perspectives of Cancer Therapeutics, Springers New York, pp. 121-148, 2009.

Wong HL, Li Y, Bendayan R, Rauth AM, Wu XY. Solid-lipid nanoparticles for antitumor drug delivery, in: Nanotechnology For Cancer Therapeutics, CRC Press. pp. 714-776, 2006.