1.         Nagar S, Remmel R, Hebbel R, Zimmerman C. Metabolism of opioids is altered in liver microsomes of sickle cell transgenic mice. Drug Metab Dispos 2004;32:98 - 104.  (pdf)

2.         Nagar S, Zalatoris JJ, Blanchard RL. Human UGT1A6 pharmacogenetics: identification of a novel SNP, characterization of allele frequencies and functional analysis of recombinant allozymes in human liver tissue and in cultured cells. Pharmacogenetics 2004 Aug;14(8):487-99. (pdf)

3.         Nagar S, Blanchard RL. Pharmacogenetics of uridine diphosphoglucuronosyltransferase (UGT) 1A family members and its role in patient response to irinotecan. Drug Metab Rev 2006;38(3):393-409. (pdf)

4.         Nagar S, Remmel RP. Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer. Oncogene 2006;25(11):1659-72. (pdf)

5.         Nagar S, Walther S, Blanchard RL. Sulfotransferase (SULT) 1A1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation. Mol Pharmacol 2006 Jun;69(6):2084-92. (pdf)

6.         Ung D, Nagar S. Variable sulfation of dietary polyphenols by recombinant human sulfotransferase (SULT) 1A1 genetic variants and SULT1E1. Drug Metab Dispos 2007 May;35(5):740-6. (pdf)

7.         Xie S, Furjanic MA, Ferrara JJ, McAndrew NR, Ardino EL, Ngondara A, Bernstein Y, Thomas KJ, Kim E, Walker JM, Nagar S, Ward SJ, and Raffa RB. The endocannabinoid system and rimonabant: a new drug with a novel mechanism of action involving cannabinoid CB1 receptor antagonism--or inverse agonism--as potential obesity treatment and other therapeutic use. J Clin Pharm Ther 2007 Jun;32(3):209-31. (pdf)

8.         Kadiev E, Mosaferirad P, Patel V, Thankachan L, Tram A, Weinlein M, Woodfin K, Raffa RB, Nagar S. Role of pharmacogenetics in variable response to drugs: focus on opioids. Expert Opinion on Drug Metabolism and Toxicology 2008; 4(1):77 – 91.(pdf)

9.         Nagar S and Raffa RB. Looking beyond the administered drug: metabolites of opioid analgesics. The Journal of Family Practice 2008; 57(6A):S1 – S8.(pdf)

10.         Argikar UA, Iwuchukwu OF, and Nagar S. Update on tools for evaluation of UGT polymorphisms. Expert Opinion on Drug Metabolism and Toxicology 2008; 4(7): 879 - 894.(pdf)