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Mercy Ramanjulu
Research Scientist
3307 N. Broad Street
Philadelphia, PA 19140
office Room 519
phone (215) 707-4918
Mercy obtained a Masters in Organic Chemistry from Bryn Mawr College in 1992 under the direction of Professor Frank B Mallory. She began her career at The Fox Chase Cancer Center, focusing her research efforts on the identification of fluorinated carbohydrates molecular probes. She later continued her career with Rhoune-Poulenc Rorer as an Associate Scientist studying in the medicinal chemistry of orally active PDE-4 inhibitors. Her work contributed to the development multiple orally active anti-inflammatory compounds. Mercy joined the parallel synthesis team at Dupont-Merck in 1997, and applied her medicinal chemistry expertise to targets associated with Alzheimer’s Disease. In 2003, Mercy joined Wyeth Research as a member of the Exploratory Chemistry Group led by Dr. Magid Abou Gharbia and John Ellingboe. Her work contributed to the development of clinical candidates across four drug discovery programs.
Publications:
Meyer, C.; Ramanjulu, M.; Carrell, H.; Glusker, J. Synthesis and X-ray Crystal structural studies of 3-D-oxy-3-fluro-b-D-allo-pyranoside, Structural Chemistry, 1997, 8, 65-71.
Mallory, F. B; Mallory, C.; Ramanjulu, M. Nuclear Spin-Spin Coupling via Nonbonded Interactions, J. Am. Chem. Soc. 2000, 122, 4108-4116.
Hulme, C; Moriarty, K; Ramanjulu, M. The Synthesis and Biological Evaluation of a Novel Series of Indole PDE4 Inhibitors, Biorg. Med. Chem. Lett. 1998, 8, 1867.
Hulme, C; Moriarty, K; Ramanjulu, M. Orally Active Indole N-Oxide PDE4 inhibitors, Biorg. Med. Chem. Lett. 1998, 8, 3053.
Thompson, L.; Liauw, A.; Ramanjulu, M. Synthesis and evaluation of succinoyl-caprolactam g-secretase inhibitors, Biorg. Med. Chem. Lett. 2006, 16, 2357.
Michael,Yang.; Ramanjulu, M. Design and synthesis of benzoazepinone-derived cyclic malonamides and aminoamides as potent g-secretase inhibitors, Biorg. Med. Chem. Lett. 2007, 17, 3910.
