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Moulder Center

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Nick Chester

Research Scientist, Moulder Center


3307 N. Broad Street

Philadelphia, PA 19140

office Room 501

phone (215) 707-1374

email nick.chester@temple.edu


Biosketch | Selected Publications

Dr. Chester received his A.B. in molecular biology from UC Berkeley in 1984. He obtained a Ph.D. in molecular biology and biochemistry from SUNY Stony Brook in 1995. His dissertation work was performed in the laboratory of Dr. Daniel Marshak at Cold Spring Harbor where he identified and characterized the three isoforms of Protein Kinase CK2 in human cells. He then did a post-doctoral fellowship in the laboratory of Dr. Phil Leder in the Genetics Department at the Harvard Medical School. While there he studied the relationship between DNA damage and cancer. His main contribution was to engineer a mouse model for the human cancer prone genetic disease, Bloom’s syndrome. He then went to industry and joined the Protein Science Department at Schering-Plough in Cambridge, MA and subsequently with Merck in West Point, PA. He worked as an associate principal scientist delivering proteins as drug targets to screening platforms and for structural analysis. His current interest is protein engineering with emphasis on antibody discovery and development of therapeutics.