RESOURCES FOR INVESTIGATORS
RESEARCH FACILITIES: PROTEOMICS RESEARCH FACILITY
Temple Proteomics Research Facility provides accessible and affordable proteomics capability for biological and biomedical research. This research facility has state-of-the-art instrumentation, and is supported by staff with expertise in proteomics, tissue microanalysis and relevant bioinformatics. Services provided include expression profiles, protein identification, posttranslational modification, characterization isolation of individual cells from tissues, protein and peptide separations, capillary electrophoresis, and multidimensional protein identification technology (MudPIT).
In addition to providing traditional two dimensional gel electrophoresis for protein expression profiling, we have implemented mass spectroscopy-based proteomics techniques using Stable Isotope Labeling of Amino Acid in Cell Culture (SILAC) and Isotope-Coded Affinity Tag (ICAT). Using the combination of these technologies, it is now possible to obtain high fidelity data for biomarkers discovery, drug targets, as well as studies on pathogenesis of diseases.
The equipment for proteomics analysis includes:
Salim Merali, PhD
Director, Proteomics Research Facility