OFFICE OF CLINICAL RESEARCH ADMINISTRATION

ACTIVE TRIALS

Cardiology

Department:	Condition (as stated in title):	PI Name:	IRB #:
Cardiology	CRT Therapy	Almendral, Jesus	13115
IRB Approval Valid Through: May 2011
Status of Trial: Open to recruitment

Cardiology	Acute Myocardial Infarction	Bashir, Riyaz	12355
A multi-center, randomized, controlled study of mechanical left ventricular uploading with counterpulsation to reduce infarct size pre-PCI for acute myocardial infarction - CRISP AMI
IRB Approval Valid Through: March 2011
Status of Trial: Open to recruitment

Cardiology	Percutaneous Coronary Intervention	Bashir, Riyaz	12755
A prospective, randomized, multi-center, double-blind trial to assess the effectiveness and safety of different durations of dual anti-platelet therapy (DAPT) in subjects undergoing percutaneous coronary intervention with the Cypher Sirolimus-Eluting Coronary Stent (Cypher Stent)
IRB Approval Valid Through: November 2010
Status of Trial: Open but closed to enrollment

Cardiology	Acute Coronary Syndrome	Brown, Michael	12593
IRB Approval Valid Through: July 2011
Status of Trial: Open to recruitment

Cardiology	Use of a Therapeutic Infusion Catheter	Brown, Michael	12863
ClearWay RX Registry
IRB Approval Valid Through: December 2010
Status of Trial: Open to recruitment

Cardiology	Heart Transplant	Fitzpatrick, James	10002
A 24 month multi-center, randomized, open-label, non-inferiority study of the efficacy and safety comparing two exposures of concentration-controlled Certican with reduced Neoral versus 3.0g MMF with standard dose Neoral in de novo heart transplant recipients
IRB Approval Valid Through: March 2011
Status of Trial: Open to recruitment

Cardiology	Heart Failure	Fitzpatrick, James	11046
Phase III, double-blind, placebo-controlled, multicenter acute study of clinical effectiveness of Nesiritide insubjects with decompensated heart failure (ASCEND-HF) A093. IND#43,998
IRB Approval Valid Through: December 2010
Status of Trial: Open to recruitment

Cardiology	Heart Transplant	Fitzpatrick, James	11638
IRB Approval Valid Through: March 2011
Status of Trial: Open to recruitment

Cardiology	CRT-D	Fitzpatrick, James	10139
IRB Approval Valid Through: April 2011
Status of Trial: Open to recruitment

Cardiology	Heart Failure	Fitzpatrick, James	13072
TEAM-HF treating to euvolemia by clinical assessment and measured blood volume in heart failure
IRB Approval Valid Through: April 2011
Status of Trial: Open to recruitment

Cardiology	Implantable Cardiovertor Defilrillators	Greenberg, Richard	12467
IRB Approval Valid Through: August 2010
Status of Trial: Open to recruitment

Cardiology	Heart Failure	Nikolaidis, Lazaros	10223
Treatment of preserved cardiac function heart failure with an Aldosterone antagonist (TOPCAT)
IRB Approval Valid Through: June 2011
Status of Trial: Open but closed to enrollment

Cardiology	Heart Failure	Nikolaidis, Lazaros	12501
A multicenter, randomized, double-blind, parallel group, placebo-controlled study to evaluate the 6 month efficacy and safety of Aliskiren therapy on top of standard therapy, on morbidity and mortality when initiated early after hospitalization for acute decompensated heart failure
IRB Approval Valid Through: July 2011
Status of Trial: Open to recruitment

Cardiology	Hyperlipidemia	Sirna, Sara	12832
IRB Approval Valid Through: January 2011
Status of Trial: Open to recruitment

Cardiology	Heart Transplant	Fitzpatrick, James	4485
IRB Approval Valid Through: July 2011
Status of Trial: Open but closed to enrollment

Date last updated: 8.05.10