OFFICE OF CLINICAL RESEARCH ADMINISTRATION

ACTIVE TRIALS

Bone Marrow Transplant

Department:	Condition (as stated in title):	PI Name:	IRB #:
Bone Marrow Transplant	Hematologic Malignancies	Emmons, Robert	12201
IRB Approval Valid Through: December 2010
Status of Trial: Open but closed to enrollment

Bone Marrow Transplant	Hematologic Malignancies	Emmons, Robert	4471
IRB Approval Valid Through: September 2010
Status of Trial: Open but closed to enrollment

Bone Marrow Transplant	Chronic Myeloid Leukemia (CML)	Emmons, Robert	11337
A phase II open-label study of the subcutaneous administration of Homoharringtonine (CGX-635) in the treatment of patients with chronic myeloid leukemia (CML) with T3151 BCR-ABL gene mutation (CGX 635-CML-202)
IRB Approval Valid Through: September 2010
Status of Trial: Open but closed to enrollment

Bone Marrow Transplant	Chronic Myeloid Leukemia (CML)	Emmons, Robert	11338
A phase II open-label study of the subcutaneous administration of Homoharringtonine (CGX-635) in the treatment of patients with chronic myeloid leukemia (CML) who have failed or are intolerant to Tyrosine Kinase Inhibitor Therapy (CGX-6350CML-203)
IRB Approval Valid Through: December 2010
Status of Trial: Open but closed to enrollment

Bone Marrow Transplant	AML	Emmons, Robert	11426
IRB Approval Valid Through: January 2011
Status of Trial: Open to recruitment

Bone Marrow Transplant	Large B-Cell Lymphoma		11664
A phase I study of the monoclonal antibody CT-011 in patients with diffuse Large B-Cell Lymphoma following autologous peripheral blood stem cell transplantation
IRB Approval Valid Through: May 2011
Status of Trial: Open but closed to enrollment

Bone Marrow Transplant	Gastrointestinal Graft Disease	Martin, Maryellen	12469
A phase I randomized, double-blind, placebo-controlled, multi-center study of the safety and efficacy of ORBEC (Oral Beciomethasone 17,21-Dippropionate) in conjunction with ten days of high-dose prednisone therapy in the treatment of patients with gastrointestinal graft vs. host disease
IRB Approval Valid Through: August 2010
Status of Trial: Open to recruitment

Date last updated: 8.05.10