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Weidong Xiao, PhD

 

Professor, Microbiology and Immunology

Professor, Sol Sherry Thrombosis Research Center

Professor, Cardiovascular Research Center

Telephone:  215-707-6392

Email: wxiao@temple.edu

 

Department of Microbiology and Immunology

Sol Sherry Thrombosis Research Center

Cardiovascular Research Center

 

Educational Background:

 

BS, Chemistry, Xiangtan University, China, 1989

 

PhD, Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC, 1996

 

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Research Interests:

 

My research has been focused on the basic biology of adeno-associated virus (AAV) and its application as a gene transfer vector for basic research and human gene therapy.


On AAV vector biology, my lab is working on two issues that are critical for the gene therapy field. One is AAV integration frequency, which has implications for AAV vector safety and its feasibility as a vector for stem cells. The other project is to understand AAV transduction mechanisms through tracking the status of AAV DNA genomes.


In addition, my lab is developing new strategies to engineer and deliver coagulation factors using AAV vectors for gene therapy of hemophilia A. Further applications of AAV vectors are also being explored.

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