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James Ryan, PhD

Professor, Physiology

Telephone:  215-707-6916

Fax:  215-707-4003

Office: Old Medical School Room 230D

Email: jryan1168@aol.com

Department of Physiology

BS, Biology, 1968

Villanova University

Villanova, PA

 

MS, Parasitology, 1970

Villanova University

Villanova, PA

 

PhD, Physiology, 1974

Hahnemann Medical College

Philadelphia, PA

 

Postdoctoral Fellowship, 1974-1975

University of Pennsylvania School of Medicine

Department of Medicine

Philadelphia, PA

 

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The research is a collaborative research interest with Dr. Henry Parkman, department of Medicine (GI Section), on the neurohumoral regulation of gastrointestinal tract smooth muscle contraction. Specific areas of interest include postnatal development, inflammatory diseases of the bowel, and regional differences in gastric smooth muscle contraction.

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

15670267. James AN, Ryan JP, Parkman HP, Effects of the selective serotonin reuptake inhibitor, fluoxetine, on regional gastric contractility. Neurogastroenterol Motil 17:1(76-82)2005 Feb

15107299. James AN, Ryan JP, Crowell MD, Parkman HP, Regional gastric contractility alterations in a diabetic gastroparesis mouse model: effects of cholinergic and serotoninergic stimulation. Am J Physiol Gastrointest Liver Physiol 287:3(G612-9)2004 Sep

15086868. James AN, Ryan JP, Parkman HP, Effects of clonidine and tricyclic antidepressants on gastric smooth muscle contractility. Neurogastroenterol Motil 16:2(143-53)2004 Apr

12660140. James AN, Ryan JP, Parkman HP, Inhibitory effects of botulinum toxin on pyloric and antral smooth muscle. Am J Physiol Gastrointest Liver Physiol 285:2(G291-7)2003 Aug

11270782. Parkman HP, Garbarino R, Ryan JP, Myosin light chain phosphorylation correlates with contractile force in guinea pig gallbladder muscle. Dig Dis Sci 46:1(176-81)2001 Jan

11181007. Parkman HP, James AN, Thomas RM, Bartula LL, Ryan JP, Myers SI, Effect of indomethacin on gallbladder inflammation and contractility during acute cholecystitis. J Surg Res 96:1(135-42)2001 Mar

10898747. Parkman HP, James AN, Ryan JP, The contractile action of platelet-activating factor on gallbladder smooth muscle. Am J Physiol Gastrointest Liver Physiol 279:1(G67-72)2000 Jul

10644487. Parkman HP, James AN, Bogar LJ, Bartula LL, Thomas RM, Ryan JP, Myers SI, Effect of acalculous cholecystitis on gallbladder neuromuscular transmission and contractility. J Surg Res 88:2(186-92)2000 Feb

10330016. Parkman HP, Pagano AP, Ryan JP, Subtypes of muscarinic receptors regulating gallbladder cholinergic contractions. Am J Physiol 276:5 Pt 1(G1243-50)1999 May

9790459. Parkman HP, Pagano AP, Ryan JP, Investigation of endogenous neurotransmitters of guinea pig gallbladder using nicotinic agonist stimulation. Dig Dis Sci 43:10(2237-43)1998 Oct

9539643. Parkman HP, Pagano AP, Ryan JP, Ranitidine and nizatidine stimulate antral smooth muscle contractility via excitatory cholinergic mechanisms. Dig Dis Sci 43:3(497-505)1998 Mar

9357837. Myers BS, Martin JS, Dempsey DT, Parkman HP, Thomas RM, Ryan JP, Acute experimental colitis decreases colonic circular smooth muscle contractility in rats. Am J Physiol 273:4 Pt 1(G928-36)1997 Oct

9331156. Parkman HP, Pagano AP, Martin JS, Ryan JP, Electric field stimulation-induced guinea pig gallbladder contractions: role of calcium channels in acetylcholine release. Dig Dis Sci 42:9(1919-25)1997 Sep

9350977. Parkman HP, Pagano AP, Ryan JP, PACAP and VIP inhibit pyloric muscle through VIP/PACAP-preferring receptors. Regul Pept 71:3(185-90)1997 Aug 29

9227479. Parkman HP, Pagano AP, Ryan JP, Dual effects of PACAP on guinea pig gallbladder muscle via PACAP-preferring and VIP/PACAP-preferring receptors. Am J Physiol 272:6 Pt 1(G1433-8)1997 Jun

9202655. Myers BS, Dempsey DT, Yasar S, Martin JS, Parkman HP, Ryan JP, Acute experimental distal colitis alters colonic transit in rats. J Surg Res 69:1(107-12)1997 Apr

8780573. Parkman HP, Pagano AP, Ryan JP, Erythromycin inhibits rabbit pyloric smooth muscle through neuronal motilin receptors. Gastroenterology 111:3(682-90)1996 Sep

8795086. Parkman HP, Pagano AP, Ringold MA, Ryan JP, Effect of modulating voltage-dependent calcium channels on cholecystokinin and acetylcholine-induced contractions of the guinea pig gallbladder. Regul Pept 63:1(31-7)1996 May 7

8825402. Ierardi JA, Paul DA, Ryan JP, Myosin light chain phosphorylation in contraction of gastric antral smooth muscle from neonate and adult rabbits. Pediatr Res 39:1(156-9)1996 Jan

7573453. Parkman HP, Pagano AP, Vozzelli MA, Ryan JP, Gastrokinetic effects of erythromycin: myogenic and neurogenic mechanisms of action in rabbit stomach. Am J Physiol 269:3 Pt 1(G418-26)1995 Sep

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