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Henry P. Parkman, MD

 

Henry P. Parkman, MD

 

Professor, Medicine

Director, GI Motility Laboratory

Telephone:  215-707-9900

FAX: 215-707-2684

Email: henryp@temple.edu

 

Department of Medicine, Section of Gastroenterology

 

Educational Background:

 

AB, Harvard University

 

MD, Case Western Reserve University

 

Internship and Residency, Johns Hopkins Hospital

 

GI Fellowship, Hospital of the University of Pennsylvania

 

GI Research Fellowship, Mayo Clinic Medical School

 

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certifications:

 

  • Internal Medicine, 1985
  • Gastroenterology, 1987
 

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clinical Interests:

 

  • Motility disorders of the esophagus, stomach, small intestine and colon
  • Clinical disorders including:

    Esophageal:  gastroesophageal reflux disease, achalasia, non-cardiac chest pain, esophageal spasm

    Gastric:  gastroparesis, functional dyspepsia

    Small bowel:  irritable bowel syndrome, intestinal pseudo-obstruction

    Colorectal:  constipation, fecal incontinence

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research interests:

 

  • Use of multichannel electrogastrography to assess gastric myoelectrical activity to detect gastric motor function in patients with dyspeptic symptoms
  • Development of a noninvasive test to measure simultaneously both gastric emptying and gastric volume after ingestion of a solid meal under physiologic conditions.  This will be useful to define the pathophysiologic factors which cause symptoms in patients with functional dyspepsia and be useful to test the effects of new pharmaceutical agents.
  • Gastric motility
  • Breath tests for gastric emptying
  • Electrogastrography (EGG)
  • New pharmaceutical treatments for gastroparesis and functional dyspepsia
  • Small bowel motility recordings
  • Esophageal pH
  • Motility recordings

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PUBMED PUBLICATIONS :


Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

24615549. Simmons K, Parkman HP, Granisetron Transdermal System Improves Refractory Nausea and Vomiting in Gastroparesis. Dig Dis Sci :()2014 Mar 11

24460884. Shin GH, Sankineni A, Parkman HP, Bolus retention in hiatal hernia identified by high-resolution esophageal manometry with impedance. Neurogastroenterol Motil 26:5(679-84)2014 May

24372829. Parkman HP, Carlson MR, Gonyer D, Metoclopramide nasal spray is effective in symptoms of gastroparesis in diabetics compared to conventional oral tablet. Neurogastroenterol Motil 26:4(521-8)2014 Apr

24368464. Parkman HP, Van Natta ML, Abell TL, McCallum RW, Sarosiek I, Nguyen L, Snape WJ, Koch KL, Hasler WL, Farrugia G, Lee L, Unalp-Arida A, Tonascia J, Hamilton F, Pasricha PJ, Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial. JAMA 310:24(2640-9)2013 Dec 25

24286121. Homko CJ, Zamora LC, Boden G, Parkman HP, Bodyweight in patients with idiopathic gastroparesis: roles of symptoms, caloric intake, physical activity, and body metabolism. Neurogastroenterol Motil 26:2(283-9)2014 Feb

24092937. Maurer AH, Camilleri M, Donohoe K, Knight LC, Madsen JL, Mariani G, Parkman HP, Van Dolsen J, The SNMMI and EANM practice guideline for small-bowel and colon transit 1.0. J Nucl Med 54:11(2004-13)2013 Nov

23721284. Parkman HP, Migraine and gastroparesis from a gastroenterologist's perspective. Headache 53 Suppl 1:(4-10)2013 Jun

23705785. Youssef AS, Argikar UA, Pathikonda M, Parkman HP, Nagar S, Identification of domperidone metabolites in plasma and urine of gastroparesis patients with LC-ESI-MS/MS. Xenobiotica 43:12(1073-83)2013 Dec

23589143. Sachdeva P, Kantor S, Knight LC, Maurer AH, Fisher RS, Parkman HP, Use of a high caloric liquid meal as an alternative to a solid meal for gastric emptying scintigraphy. Dig Dis Sci 58:7(2001-6)2013 Jul

23456496. Parkman HP, Yates K, Hasler WL, Nguyen L, Pasricha PJ, Snape WJ, Farrugia G, Koch KL, Calles J, Abell TL, Sarosiek I, McCallum RW, Lee L, Unalp-Arida A, Tonascia J, Hamilton F, Cholecystectomy and clinical presentations of gastroparesis. Dig Dis Sci 58:4(1062-73)2013 Apr

23426455. Friedenberg FK, Kowalczyk M, Parkman HP, The influence of race on symptom severity and quality of life in gastroparesis. J Clin Gastroenterol 47:9(757-61)2013 Oct

23358845. Keller DS, Parkman HP, Boucek DO, Sankineni A, Meilahn JE, Gaughan JP, Harbison S, Surgical outcomes after gastric electric stimulator placement for refractory gastroparesis. J Gastrointest Surg 17:4(620-6)2013 Apr

23181386. Sankineni A, Salieb L, Harrison M, Fisher RS, Parkman HP, Slow esophageal propagation velocity: association with dysphagia for solids. Neurogastroenterol Motil 25:1(e44-51)2013 Jan

23053897. George NS, Sankineni A, Parkman HP, Small intestinal bacterial overgrowth in gastroparesis. Dig Dis Sci 59:3(645-52)2014 Mar

22688145. Parkman HP, Mishra A, Jacobs M, Pathikonda M, Sachdeva P, Gaughan J, Krynetskiy E, Clinical response and side effects of metoclopramide: associations with clinical, demographic, and pharmacogenetic parameters. J Clin Gastroenterol 46:6(494-503)2012 Jul

22669206. Cherian D, Paladugu S, Pathikonda M, Parkman HP, Fatigue: a prevalent symptom in gastroparesis. Dig Dis Sci 57:8(2088-95)2012 Aug

22590983. Tang DM, Pathikonda M, Harrison M, Fisher RS, Friedenberg FK, Parkman HP, Symptoms and esophageal motility based on phenotypic findings of scleroderma. Dis Esophagus 26:2(197-203)2013 Feb-Mar

22293162. Parkman HP, Scintigraphy for evaluation of patients for GI motility disorders--the referring physician's perspective. Semin Nucl Med 42:2(76-8)2012 Mar

22179054. Wang D, Parkman HP, Jacobs MR, Mishra AK, Krynetskiy E, Obradovic Z, DNA microarray SNP associations with clinical efficacy and side effects of domperidone treatment for gastroparesis. J Biomed Inform 45:2(316-22)2012 Apr

22118574. Cherian D, Parkman HP, Nausea and vomiting in diabetic and idiopathic gastroparesis. Neurogastroenterol Motil 24:3(217-22, e103)2012 Mar

22011587. Shahid S, Ramzan Z, Maurer AH, Parkman HP, Fisher RS, Chronic idiopathic constipation: more than a simple colonic transit disorder. J Clin Gastroenterol 46:2(150-4)2012 Feb

21966890. Sawaya RA, Macgill A, Parkman HP, Friedenberg FK, Use of the Montreal global definition as an assessment of quality of life in reflux disease. Dis Esophagus 25:6(477-83)2012 Aug

21959322. Pathikonda M, Sachdeva P, Malhotra N, Fisher RS, Maurer AH, Parkman HP, Gastric emptying scintigraphy: is four hours necessary? J Clin Gastroenterol 46:3(209-15)2012 Mar

21871247. Parkman HP, Yates K, Hasler WL, Nguyen L, Pasricha PJ, Snape WJ, Farrugia G, Koch KL, Calles J, Abell TL, McCallum RW, Lee L, Unalp-Arida A, Tonascia J, Hamilton F, Similarities and differences between diabetic and idiopathic gastroparesis. Clin Gastroenterol Hepatol 9:12(1056-64; quiz e133-4)2011 Dec

21735078. Ramzan Z, Duffy F, Gomez J, Fisher RS, Parkman HP, Continuous glucose monitoring in gastroparesis. Dig Dis Sci 56:9(2646-55)2011 Sep

21684286. Parkman HP, Yates KP, Hasler WL, Nguyan L, Pasricha PJ, Snape WJ, Farrugia G, Calles J, Koch KL, Abell TL, McCallum RW, Petito D, Parrish CR, Duffy F, Lee L, Unalp-Arida A, Tonascia J, Hamilton F, Dietary intake and nutritional deficiencies in patients with diabetic or idiopathic gastroparesis. Gastroenterology 141:2(486-98, 498.e1-7)2011 Aug

21540031. Parkman HP, Hasler WL, Nguyen L, Pasricha PJ, Snape WJ, Farrugia G, Koch KL, Abell TL, McCallum RW, Yates K, Lee L, Unalp-Arida A, Tonascia J, Hamilton F, Reply. Gastroenterology :()2011 Apr 27

21365240. Sachdeva P, Malhotra N, Pathikonda M, Khayyam U, Fisher RS, Maurer AH, Parkman HP, Gastric emptying of solids and liquids for evaluation for gastroparesis. Dig Dis Sci 56:4(1138-46)2011 Apr

21332597. Verrengia M, Sachdeva P, Gaughan J, Fisher RS, Parkman HP, Variation of symptoms during the menstrual cycle in female patients with gastroparesis. Neurogastroenterol Motil 23:7(625-e254)2011 Jul

21063774. Parkman HP, Jacobs MR, Mishra A, Hurdle JA, Sachdeva P, Gaughan JP, Krynetskiy E, Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects. Dig Dis Sci 56:1(115-24)2011 Jan

20965184. Parkman HP, Yates K, Hasler WL, Nguyen L, Pasricha PJ, Snape WJ, Farrugia G, Koch KL, Abell TL, McCallum RW, Lee L, Unalp-Arida A, Tonascia J, Hamilton F, Clinical features of idiopathic gastroparesis vary with sex, body mass, symptom onset, delay in gastric emptying, and gastroparesis severity. Gastroenterology 140:1(101-15)2011 Jan

20733513. Jaffe JK, Paladugu S, Gaughan JP, Parkman HP, Characteristics of nausea and its effects on quality of life in diabetic and idiopathic gastroparesis. J Clin Gastroenterol 45:4(317-21)2011 Apr

20472097. Cherian D, Sachdeva P, Fisher RS, Parkman HP, Abdominal pain is a frequent symptom of gastroparesis. Clin Gastroenterol Hepatol 8:8(676-81)2010 Aug

20339562. Vegesna A, Besetty R, Kalra A, Farooq U, Korimilli A, Chuang KY, Fisher R, Parkman H, Miller L, Induced opening of the gastroesophageal junction occurs at a lower gastric pressure in gerd patients and in hiatal hernia subjects than in normal control subjects. Gastroenterol Res Pract 2010:(857654)2010

20215751. Doma S, Paladugu S, Parkman HP, Friedenberg FK, Wireless capsules for esophageal pH monitoring: are we placing them correctly? Digestion 82:1(54-9)2010

20082665. Khayyam U, Sachdeva P, Gomez J, Ramzan Z, Smith MS, Maurer AH, Fisher RS, Parkman HP, Assessment of symptoms during gastric emptying scintigraphy to correlate symptoms to delayed gastric emptying. Neurogastroenterol Motil 22:5(539-45)2010 May

20003077. Parkman HP, Camilleri M, Farrugia G, McCallum RW, Bharucha AE, Mayer EA, Tack JF, Spiller R, Horowitz M, Vinik AI, Galligan JJ, Pasricha PJ, Kuo B, Szarka LA, Marciani L, Jones K, Parrish CR, Sandroni P, Abell T, Ordog T, Hasler W, Koch KL, Sanders K, Norton NJ, Hamilton F, Gastroparesis and functional dyspepsia: excerpts from the AGA/ANMS meeting. Neurogastroenterol Motil 22:2(113-33)2010 Feb

19997977. Korimilli A, Parkman HP, Effect of atilmotin, a motilin receptor agonist, on esophageal, lower esophageal sphincter, and gastric pressures. Dig Dis Sci 55:2(300-6)2010 Feb

19997975. Harberson J, Thomas RM, Harbison SP, Parkman HP, Gastric neuromuscular pathology in gastroparesis: analysis of full-thickness antral biopsies. Dig Dis Sci 55:2(359-70)2010 Feb

19911235. Kowalczyk M, Parkman H, Ward L, Adult cyclic vomiting syndrome successfully treated with intranasal sumatriptan. J Gen Intern Med 25:1(88-91)2010 Jan

19760157. Uppalapati SS, Ramzan Z, Fisher RS, Parkman HP, Factors contributing to hospitalization for gastroparesis exacerbations. Dig Dis Sci 54:11(2404-9)2009 Nov

19655250. Maqbool S, Parkman HP, Friedenberg FK, Wireless capsule motility: comparison of the SmartPill GI monitoring system with scintigraphy for measuring whole gut transit. Dig Dis Sci 54:10(2167-74)2009 Oct

19575604. Ung D, Parkman HP, Nagar S, Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis. Xenobiotica 39:10(749-56)2009 Oct

19293005. Parkman HP, Jones MP, Tests of gastric neuromuscular function. Gastroenterology 136:5(1526-43)2009 May

19232287. Parkman HP, Orr WC, The gastrointestinal motility laboratory. Gastrointest Endosc Clin N Am 19:1(171-84, viii)2009 Jan

19232280. Parkman HP, Assessment of gastric emptying and small-bowel motility: scintigraphy, breath tests, manometry, and SmartPill. Gastrointest Endosc Clin N Am 19:1(49-55, vi)2009 Jan

19033686. Cassilly DW, Wang YR, Friedenberg FK, Nelson DB, Maurer AH, Parkman HP, Symptoms of gastroparesis: use of the gastroparesis cardinal symptom index in symptomatic patients referred for gastric emptying scintigraphy. Digestion 78:2-3(144-51)2008

18942041. Ung D, Cowan A, Parkman HP, Nagar S, Lack of interaction between metoclopramide and morphine in vitro and in mice. Xenobiotica 38:11(1365-76)2008 Nov

18829390. Friedenberg FK, Parkman HP, Persistent nausea and abdominal pain in a patient with delayed gastric emptying. Clin Gastroenterol Hepatol 6:12(1309-14)2008 Dec

18378499. Mekapati J, Knight LC, Maurer AH, Fisher RS, Parkman HP, Transsphincteric pH profile at the gastroesophageal junction. Clin Gastroenterol Hepatol 6:6(630-4)2008 Jun

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