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Lazaros Nikolaidis, MD

Assistant Professor, Medicine

Telephone:  215-707-1503

FAX: 215-707-3946

Email: lnikolai@temple.edu

Department of Medicine, Section of Cardiology

MD, National Kapodistrian University, Athens, Greece

 

Fellowship in heart failure, American Heart Association

 

Received regional and national junior investigator awards from the American Heart Association, the Pittsburgh Foundation and the Heart Failure Society of America

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• Advanced heart failure and transplant

• Research predominantly on neurohormonal mechanisms, vascular function and myocardial metabolism in cardiomyopathy with emphasis on the translational approach

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• Board certified in Internal Medicine, Cardiovascular Diseases, Nuclear Cardiology and Echocardiology

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Instructor of medicine at Drexel University College of Medicine, Allegheny General Hospital, Pittsburgh, PA

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

17174230. Sokos GG, Nikolaidis LA, Mankad S, Elahi D, Shannon RP, Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure. J Card Fail 12:9(694-9)2006 Dec

16842525. Leech SH, Lopez-Cepero M, LeFor WM, DiChiara L, Weston M, Furukawa S, Macha M, Singhal A, Wald JW, Nikolaidis LA, McClurken JB, Bove AA, Management of the sensitized cardiac recipient: the use of plasmapheresis and intravenous immunoglobulin. Clin Transplant 20:4(476-84)2006 Jul-Aug

16682315. Nikolaidis LA, Poornima I, Parikh P, Magovern M, Shen YT, Shannon RP, The effects of combined versus selective adrenergic blockade on left ventricular and systemic hemodynamics, myocardial substrate preference, and regional perfusion in conscious dogs with dilated cardiomyopathy. J Am Coll Cardiol 47:9(1871-81)2006 May 2

16123310. Parikh P, Nikolaidis LA, Stolarski C, Shen YT, Shannon RP, Chronic exposure to cocaine binging predisposes to an accelerated course of dilated cardiomyopathy in conscious dogs following rapid ventricular pacing. J Pharmacol Exp Ther 315:3(1013-9)2005 Dec

16024574. Nikolaidis LA, Elahi D, Shen YT, Shannon RP, Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 289:6(H2401-8)2005 Dec

15880342. Nikolaidis LA, Mathier MA, Doverspike A, Hentosz T, Huerbin R, Stolarski CJ, Shannon RP, Coronary blood flow responses are impaired independent of NO and endothelial function in conscious dogs with dilated cardiomyopathy. J Card Fail 11:4(313-21)2005 May

15356213. Nikolaidis LA, Doverspike A, Hentosz T, Zourelias L, Shen YT, Elahi D, Shannon RP, Glucagon-like peptide-1 limits myocardial stunning following brief coronary occlusion and reperfusion in conscious canines. J Pharmacol Exp Ther 312:1(303-8)2005 Jan

15313949. Nikolaidis LA, Elahi D, Hentosz T, Doverspike A, Huerbin R, Zourelias L, Stolarski C, Shen YT, Shannon RP, Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy. Circulation 110:8(955-61)2004 Aug 24

15197425. Nikolaidis LA, Azzouz M, Friedlander L, Van Thiel DH, Gradman AH, Hepatitis C virus-associated pericardial effusion and tamponade in a liver transplant recipient. Can J Cardiol 20:7(719-21)2004 May 15

15182765. Nikolaidis LA, Trumble D, Hentosz T, Doverspike A, Huerbin R, Mathier MA, Shen YT, Shannon RP, Catecholamines restore myocardial contractility in dilated cardiomyopathy at the expense of increased coronary blood flow and myocardial oxygen consumption (MvO2 cost of catecholamines in heart failure). Eur J Heart Fail 6:4(409-19)2004 Jun

15078585. Nikolaidis LA, Levine TB, Peroxisome proliferator activator receptors (PPAR), insulin resistance, and cardiomyopathy: friends or foes for the diabetic patient with heart failure? Cardiol Rev 12:3(158-70)2004 May-Jun

14981009. Nikolaidis LA, Mankad S, Sokos GG, Miske G, Shah A, Elahi D, Shannon RP, Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion. Circulation 109:8(962-5)2004 Mar 2

14736546. Nikolaidis LA, Sturzu A, Stolarski C, Elahi D, Shen YT, Shannon RP, The development of myocardial insulin resistance in conscious dogs with advanced dilated cardiomyopathy. Cardiovasc Res 61:2(297-306)2004 Feb 1

12057995. Nikolaidis LA, Doverspike A, Huerbin R, Hentosz T, Shannon RP, Angiotensin-converting enzyme inhibitors improve coronary flow reserve in dilated cardiomyopathy by a bradykinin-mediated, nitric oxide-dependent mechanism. Circulation 105:23(2785-90)2002 Jun 11

12032577. Nikolaidis LA, Kounis NG, Gradman AH, Allergic angina and allergic myocardial infarction: a new twist on an old syndrome. Can J Cardiol 18:5(508-11)2002 May

11828172. Nikolaidis LA, When cancer and heart failure cross paths: a case report of severe cardiorenal compromise associated with the anti-CD20 monoclonal antibody rituximab in a patient with dilated cardiomyopathy. Congest Heart Fail 7:4(223-227)2001 Jul

11827690. Nikolaidis LA, Hentosz T, Doverspike A, Huerbin R, Stolarski C, Shen YT, Shannon RP, Catecholamine stimulation is associated with impaired myocardial O(2) utilization in heart failure. Cardiovasc Res 53:2(392-404)2002 Feb 1

11709392. Nikolaidis LA, Hentosz T, Doverspike A, Huerbin R, Stolarski C, Shen YT, Shannon RP, Mechanisms whereby rapid RV pacing causes LV dysfunction: perfusion-contraction matching and NO. Am J Physiol Heart Circ Physiol 281:6(H2270-81)2001 Dec

7499184. Nikolaidis LA, Leon MN, Paslidis NJ, Acute pancreatitis as the first manifestation of hyperparathyroidism in an otherwise asymptomatic patient. J Ark Med Soc 92:6(273-5)1995 Nov

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