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Ming-Lin Liu, MD, PhD

Assistant Professor (Research), Medicine

Telephone:  215-707-3387

FAX: 215-707-5599

Email:  minglin.liu@temple.edu

Department of Medicine, Section of Endocrinology, Diabetes and Metabolism

MD, Tianjin Medical University, Tianjin, China, 1986

 

Residency, Tianjin Medical University General Hospital, Tianjin, China, 1986-1993

 

PhD, University of Helsinki, Helsinki, Finland, 2003

 

Postdoctoral Fellowship, Thomas Jefferson University, Philadelphia, PA, 2003-2006

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Basic and clinical research in cardiovascular, dyslipidemic and diabetic diseases

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• Member, American Heart Association, Council on Arteriosclerosis, Thrombosis and Vascular Biology
• Member, American Stroke Association
• Member, American Diabetes Association
• Member, European Atherosclerosis Society
• Editorial Board Member, American Journal of Cardiovascular Disease
• Editorial Board Member, Journal of Diabetes Research and Clinical Metabolism
• Editorial Board Member, World Journal of Hematology

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22248645, Liu ML*. Williams KJ. Microvesicles: potential markers and mediators of endothelial dysfunction. Current Opinion in Endocrinology, Diabetes and Obesity. 2012 Jan 12. [Epub ahead of print] (*corresponding author)

21049473. Chen K, Liu ML, Schaffer L, Li MZ, Williams KJ. Type 2 diabetes in mice induces hepatic overexpression of sulfatase 2, a novel factor that suppresses uptake of remnant lipoproteins. Hepatology. 2010;52:1957-1967.

20558816. Li MZ, Yu DM, Williams KJ, Liu ML*. Tobacco Smoke Induces the Generation of Procoagulant Microvesicles from Human Monocytes/Macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Sep; 30(9):1818-24. (*corresponding author)

Song JQ, Liu ML, Liu YX. Microvesicle as a novel mediator of cell-to-cell communication and its roles in cardiovascular diseases. Progress in Physiological Sciences. 2010;41(5): 376-379. (Chinese, 2225694)

18314464. Moren X, Deakin S, Liu ML, Taskinen MR and James RW. HDL subfraction distribution of paraoxonase-1 and its relevance to enzyme activity and resistance to oxidative stress. Journal of Lipid Research. 2008;49(6):1246-53

Liu ML, Cholesterol-induced membrane microvesicles: novel contributors to atherothrombosis. (commentaries) Website of International Atherosclerosis Society, 2007 May. http://www.athero.org/commentaries/comm654.asp

17158353. Liu ML*, Reilly MP, Peter Casasanto, McKenzie SE, Williams KJ*. Cholesterol Enrichment of Human Monocyte/Macrophages Induces Surface Exposure of Phosphatidylserine and the Release of Biologically-Active Tissue Factor-Positive Microvesicles. Arteriosclerosis, Thrombosis, and Vascular Biology. 2007; 27(2):430-5. (*co-corresponding authors)

15793251. Williams KJ*, Liu ML*, Zhu Y, Xu X, Davidson WR, McCue P, Sharma K. Loss of heparan N-sulfotransferase in diabetic liver: role of angiotensin II. Diabetes. 2005; 54(4):1116-22 (*co-corresponding authors)

15242240. Liu ML, James RW, Ylitalo K, Taskinen MR. Associations Between Parameters of HDL Oxidation in vitro and Paraoxonase and Paraoxonase-1 Gene Polymorphisms in Familial Combined Hyperlipidemic Family Members. Nutrition Metabolism and Cardiovascular Disease. 2004; 14(2):81-7.

15205217 Liu ML, Ylitalo K, Salonen R, Salonen JT, Taskinen MR. Circulating oxidized LDL and its association with Carotid Intima-Media Thickness in Asymptomatic Members of Familial Combined Hyperlipidemia Families. Arteriosclerosis, Thrombosis, and Vascular Biology. 2004; 24(8):1492-7.

Liu ML. LDL oxidation and LDL particle size in the development of atherosclerosis. Helsinki University Press, Helsinki, Finland, 2002. (Academic dissertation). http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/liu/ldloxida.pdf  

11988600 Liu ML, Ylitalo K, Nuotio I, Salonen R, Salonen JT, Taskinen MR. Association Between Carotid Intima-Media Thickness and LDL Size and Susceptibility of LDL to Oxidation in Asymptomatic Members of Familial Combined Hyperlipidemia Families. Stroke. 2002; 33: 1255-60

12014434 Liu ML, Ylitalo K, Vakkilainen J, Nuotio I, Valkonen M, Lahdenperä S, Viikari J, Taskinen MR. LDL Particle Size and Susceptibility of LDL to Oxidation in vitro in Patients with Familial Combined Hyperlipidemia. Annals of Medicine. 2002, 34: 48-54

10488962 Bergholm R, Makimattila S, Valkonen M, Liu ML, Lahdenpera S, Taskinen MR, Sovijarvi A, Malmberg P, Yki-Jarvinen H. Intense physical training decreases circulating antioxidants and endothelium-dependent vasodilatation in vivo. Atherosclerosis. 1999; 145(2): 341-9.

10372251 Makimattila S, Liu ML, Vakkilainen J, Schlenzka A, Lahdenpera S, Syvanne M, Mantysaari M, Summanen P, Bergholm R, Taskinen MR, Yki-Jarvinen H. Impaired endothelium-dependent vasodilation in type 2 diabetes. Relation to LDL size, oxidized LDL, and antioxidants. Diabetes Care. 1999;22(6):973-81.

10362621 Liu ML, Bergholm R, Makimattila S, Lahdenpera S, Valkonen M, Hilden H, Yki-Jarvinen H, Taskinen MR. A marathon run increases the susceptibility of LDL to oxidation in vitro and modifies plasma antioxidants. American Journal of Physiology. 1999; 276(6 Pt 1):E1083-91.

Liu ML, Cao ZH: Erythrocyte Superoxide Dismutase and Plasma lipid peroxides in the patients with coronary heart disease. Journal of Tianjin Medical College. 1993; 17(4):  33-35. (Chinese)

Liu ML, Cao ZH, Yao CH. Erythrocyte Superoxide Dismutase and Plasma lipid peroxides in the patients with acute myocardial infarction after administration of thrombolytic therapy.  Clinical Focus. 1993; 8(9,10):  96-99. (Chinese)

Liu ML. Myocardial ischemic-reperfusion injury and free radicals. Tianjin Medical journal. 1993; 21(9): 570-73. (Chinese)

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