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Larry R. Kaiser, MD, FACS

Dean, Temple University School of Medicine

Senior Executive Vice President for the Health Sciences

President and CEO, Temple University Health System

Professor, Surgery

Telephone:  215-707-8773

Email: larry.kaiser@temple.edu

Department of Surgery, Section of Thoracic Surgery

BS, Tulane University, New Orleans, Louisiana, 1973

 

MD, Tulane University School of Medicine, New Orleans, LA, 1977

 

Internship, Surgery, University of California, Los Angeles, CA, 1978

 

Residency, Surgery, University of California, Los Angeles, CA, 1979

 

Postgraduate Research Fellowship, Surgical Oncology, 1981-1982

 

Residency, Cardiovascular Surgery, University of Toronto, Toronto, Canada, 1983-1984

 

Residency, Thoracic Surgery, University of Toronto, Canada, 1984-1985

 

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• Lung cancer
• Mediastinal tumors
• Mesothelioma
• Myasthenia gravis

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• Surgery
• Thoracic and cardiac surgery

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• American Association for Thoracic Surgery
• American Surgical Association
• Society of Thoracic Surgeons
• Society of Surgical Oncology
• Institute of Medicine
• The Halsted Society
• Fleischner Society
• American Thoracic Society
• American College of Chest Physicians
• American College of Radiology
• American College of Surgeons
• American Society for Clinical Oncology
• Longmire Surgical Society
• Society of Clinical Surgery
• Society of University Surgeons
• Pennsylvania Medical Society
• Philadelphia Academy of Surgery

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

22288043. Banki F, Schniederjan R, Feng W, Kaiser LR, Mediastinal mature teratoma in a Jehovah's Witness: Discrepancy between imaging and intraoperative findings. Int J Surg Case Rep 3:2(49-51)2012

22130619. Cen P, Banki F, Cheng L, Khalil K, Du XL, Fallon M, Amato RJ, Kaiser LR, Changes in age, stage distribution, and survival of patients with esophageal adenocarcinoma over three decades in the United States. Ann Surg Oncol 19:5(1685-91)2012 May

22121536. Kaiser LR, Donor lung allocation: who shall live; who shall die? Arch Surg 146:10(1209-10)2011 Oct

21750417. Predina JD, Puc MM, Bergey MR, Sonnad SS, Kucharczuk JC, Staddon A, Kaiser LR, Shrager JB, Improved survival after pulmonary metastasectomy for soft tissue sarcoma. J Thorac Oncol 6:5(913-9)2011 May

20951248. Singla S, Litzky LA, Kaiser LR, Shrager JB, Should asymptomatic enlarged thymus glands be resected? J Thorac Cardiovasc Surg 140:5(977-83)2010 Nov

20833824. Levine S, Biswas C, Dierov J, Barsotti R, Shrager JB, Nguyen T, Sonnad S, Kucharchzuk JC, Kaiser LR, Singhal S, Budak MT, Increased proteolysis, myosin depletion, and atrophic AKT-FOXO signaling in human diaphragm disuse. Am J Respir Crit Care Med 183:4(483-90)2011 Feb 15

20739855. Kelz RR, Mullen JL, Kaiser LR, Pray LA, Shea GP, Drebin JA, Wirtalla CJ, Morris JB, Prevention of surgical resident attrition by a novel selection strategy. Ann Surg 252:3(537-1; discussion 541-3)2010 Sep

20723727. Sanchez PG, Kucharczuk JC, Su S, Kaiser LR, Cooper JD, National Emphysema Treatment Trial redux: accentuating the positive. J Thorac Cardiovasc Surg 140:3(564-72)2010 Sep

20502187. Montone KT, Litzky LA, Feldman MD, Peterman H, Mathis B, Baliff J, Kaiser LR, Kucharczuk J, Nachamkin I, In situ hybridization for Coccidioides immitis 5.8S ribosomal RNA sequences in formalin-fixed, paraffin-embedded pulmonary specimens using a locked nucleic acid probe: a rapid means for identification in tissue sections. Diagn Mol Pathol 19:2(99-104)2010 Jun

20417762. Estrera AL, Miller CC, Kaneko T, Lee TY, Walkes JC, Kaiser LR, Safi HJ, Outcomes of acute type a aortic dissection after previous cardiac surgery. Ann Thorac Surg 89:5(1467-74)2010 May

19174661. Kennedy DW, Kagan SH, Abramson KB, Boberick C, Kaiser LR, Academic medicine amenities unit: developing a model to integrate academic medical care with luxury hotel services. Acad Med 84:2(185-91)2009 Feb

19074893. Kim S, Buchlis G, Fridlender ZG, Sun J, Kapoor V, Cheng G, Haas A, Cheung HK, Zhang X, Corbley M, Kaiser LR, Ling L, Albelda SM, Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy. Cancer Res 68:24(10247-56)2008 Dec 15

19059183. Foley PJ, Roses RE, Kelz RR, Resnick AS, Williams NN, Mullen JL, Kaiser LR, Morris JB, The state of general surgery training: a different perspective. J Surg Educ 65:6(494-8)2008 Nov-Dec

18571141. Resnick AS, Disbot M, Wurster A, Mullen JL, Kaiser LR, Morris JB, Contributions of surgical residents to patient satisfaction: impact of residents beyond clinical care. J Surg Educ 65:3(243-52)2008 May-Jun

18567885. Khicha SG, Kaiser LR, Shrager JB, Extended transcervical thymectomy in the treatment of myasthenia gravis. Ann N Y Acad Sci 1132:(336-43)2008

18559619. Wallace A, Kapoor V, Sun J, Mrass P, Weninger W, Heitjan DF, June C, Kaiser LR, Ling LE, Albelda SM, Transforming growth factor-beta receptor blockade augments the effectiveness of adoptive T-cell therapy of established solid cancers. Clin Cancer Res 14:12(3966-74)2008 Jun 15

18514128. Kaiser LR, Surgical treatment of thymic epithelial neoplasms. Hematol Oncol Clin North Am 22:3(475-88)2008 Jun

18463540. Kim S, Fridlender ZG, Dunn R, Kehry MR, Kapoor V, Blouin A, Kaiser LR, Albelda SM, B-cell depletion using an anti-CD20 antibody augments antitumor immune responses and immunotherapy in nonhematopoetic murine tumor models. J Immunother 31:5(446-57)2008 Jun

18435039. Kaiser LR, What's New in ACS Surgery: principles and practice. Bull Am Coll Surg 89:10(25-7)2004 Oct

18367735. Levine S, Nguyen T, Taylor N, Friscia ME, Budak MT, Rothenberg P, Zhu J, Sachdeva R, Sonnad S, Kaiser LR, Rubinstein NA, Powers SK, Shrager JB, Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. N Engl J Med 358:13(1327-35)2008 Mar 27

17765353. Gooneratne NS, Dean GE, Rogers AE, Nkwuo JE, Coyne JC, Kaiser LR, Sleep and quality of life in long-term lung cancer survivors. Lung Cancer 58:3(403-10)2007 Dec

17671130. Sterman DH, Recio A, Carroll RG, Gillespie CT, Haas A, Vachani A, Kapoor V, Sun J, Hodinka R, Brown JL, Corbley MJ, Parr M, Ho M, Pastan I, Machuzak M, Benedict W, Zhang XQ, Lord EM, Litzky LA, Heitjan DF, June CH, Kaiser LR, Vonderheide RH, Albelda SM, Kanther M, A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses. Clin Cancer Res 13:15 Pt 1(4456-66)2007 Aug 1

17504990. Vachani A, Nebozhyn M, Singhal S, Alila L, Wakeam E, Muschel R, Powell CA, Gaffney P, Singh B, Brose MS, Litzky LA, Kucharczuk J, Kaiser LR, Marron JS, Showe MK, Albelda SM, Showe LC, A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma. Clin Cancer Res 13:10(2905-15)2007 May 15

17426615. Wurster AB, Pearson K, Sonnad SS, Mullen JL, Kaiser LR, The Patient Safety Leadership Academy at the University of Pennsylvania: the first cohort's learning experience. Qual Manag Health Care 16:2(166-73)2007 Apr-Jun

17409825. Rosenthal DI, Fuller CD, Machtay M, Algazy KM, Meyer DM, Kaiser LR, Yardley DA, Loiacano ME, Carbone DP, Phase I study of Paclitaxel given by seven-week continuous infusion concurrent with radiation therapy for locally advanced non-small cell lung cancer. J Thorac Oncol 1:1(38-45)2006 Jan

17307476. Kreider ME, Hansen-Flaschen J, Ahmad NN, Rossman MD, Kaiser LR, Kucharczuk JC, Shrager JB, Complications of video-assisted thoracoscopic lung biopsy in patients with interstitial lung disease. Ann Thorac Surg 83:3(1140-4)2007 Mar

17184673. Friscia ME, Zhu J, Kolff JW, Chen Z, Kaiser LR, Deutschman CS, Shrager JB, Cytokine response is lower after lung volume reduction through bilateral thoracoscopy versus sternotomy. Ann Thorac Surg 83:1(252-6)2007 Jan

17084771. Resnick AS, Mullen JL, Kaiser LR, Morris JB, Patterns and predictions of resident misbehavior--a 10-year retrospective look. Curr Surg 63:6(418-25)2006 Nov-Dec

17080181. Sterman DH, Gillespie CT, Carroll RG, Coughlin CM, Lord EM, Sun J, Haas A, Recio A, Kaiser LR, Coukos G, June CH, Albelda SM, Vonderheide RH, Interferon beta adenoviral gene therapy in a patient with ovarian cancer. Nat Clin Pract Oncol 3:11(633-9)2006 Nov

17062262. Shrager JB, Nathan D, Brinster CJ, Yousuf O, Spence A, Chen Z, Kaiser LR, Outcomes after 151 extended transcervical thymectomies for myasthenia gravis. Ann Thorac Surg 82:5(1863-9)2006 Nov

16777998. Levine S, Nguyen T, Friscia M, Zhu J, Szeto W, Kucharczuk JC, Tikunov BA, Rubinstein NA, Kaiser LR, Shrager JB, Parasternal intercostal muscle remodeling in severe chronic obstructive pulmonary disease. J Appl Physiol 101:5(1297-302)2006 Nov

16488193. Wilderman MJ, Kim S, Gillespie CT, Sun J, Kapoor V, Vachani A, Sterman DH, Kaiser LR, Albelda SM, Blockade of TNF-alpha decreases both inflammation and efficacy of intrapulmonary Ad.IFNbeta immunotherapy in an orthotopic model of bronchogenic lung cancer. Mol Ther 13:5(910-7)2006 May

16357188. Jassar AS, Suzuki E, Kapoor V, Sun J, Silverberg MB, Cheung L, Burdick MD, Strieter RM, Ching LM, Kaiser LR, Albelda SM, Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma. Cancer Res 65:24(11752-61)2005 Dec 15

16305836. O'Brien PK, Kucharczuk JC, Marshall MB, Friedberg JS, Chen Z, Kaiser LR, Shrager JB, Comparative study of subxiphoid versus video-thoracoscopic pericardial "window". Ann Thorac Surg 80:6(2013-9)2005 Dec

16243818. Sterman DH, Recio A, Vachani A, Sun J, Cheung L, DeLong P, Amin KM, Litzky LA, Wilson JM, Kaiser LR, Albelda SM, Long-term follow-up of patients with malignant pleural mesothelioma receiving high-dose adenovirus herpes simplex thymidine kinase/ganciclovir suicide gene therapy. Clin Cancer Res 11:20(7444-53)2005 Oct 15

16236940. Ochroch EA, Gottschalk A, Augoustides JG, Aukburg SJ, Kaiser LR, Shrager JB, Pain and physical function are similar following axillary, muscle-sparing vs posterolateral thoracotomy. Chest 128:4(2664-70)2005 Oct

16192813. Resnick AS, Corrigan D, Mullen JL, Kaiser LR, Surgeon contribution to hospital bottom line: not all are created equal. Ann Surg 242:4(530-7; discussion 537-9)2005 Oct

16166452. Suzuki E, Kapoor V, Jassar AS, Kaiser LR, Albelda SM, Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res 11:18(6713-21)2005 Sep 15

16166316. Wilderman MJ, Sun J, Jassar AS, Kapoor V, Khan M, Vachani A, Suzuki E, Kinniry PA, Sterman DH, Kaiser LR, Albelda SM, Intrapulmonary IFN-beta gene therapy using an adenoviral vector is highly effective in a murine orthotopic model of bronchogenic adenocarcinoma of the lung. Cancer Res 65:18(8379-87)2005 Sep 15

15978426. Kucharczuk JC, Kaiser LR, Radical lobectomy, esophagectomy, and mediastinal dissections for intrathoracic malignancy. Surg Oncol Clin N Am 14:3(499-509, vi)2005 Jul

15937803. Lee LS, Nance M, Kaiser LR, Kucharczuk JC, Familial massive leiomyoma with esophageal leiomyomatosis: an unusual presentation in a father and his 2 daughters. J Pediatr Surg 40:5(e29-32)2005 May

15930332. Singhal S, Vachani A, Antin-Ozerkis D, Kaiser LR, Albelda SM, Prognostic implications of cell cycle, apoptosis, and angiogenesis biomarkers in non-small cell lung cancer: a review. Clin Cancer Res 11:11(3974-86)2005 Jun 1

15784370. Marshall MB, Ahmed Z, Kucharczuk JC, Kaiser LR, Shrager JB, Catamenial pneumothorax: optimal hormonal and surgical management. Eur J Cardiothorac Surg 27:4(662-6)2005 Apr

15622005. Tanaka T, Delong PA, Amin K, Henry A, Kruklitis R, Kapoor V, Kaiser LR, Albelda SM, Treatment of lung cancer using clinically relevant oral doses of the cyclooxygenase-2 inhibitor rofecoxib: potential value as adjuvant therapy after surgery. Ann Surg 241:1(168-78)2005 Jan

15501267. Kaiser LR, Mullen JL, Surgical education in the new millennium: the university perspective. Surg Clin North Am 84:6(1425-39, vii)2004 Dec

15355924. Suzuki E, Kapoor V, Cheung HK, Ling LE, DeLong PA, Kaiser LR, Albelda SM, Soluble type II transforming growth factor-beta receptor inhibits established murine malignant mesothelioma tumor growth by augmenting host antitumor immunity. Clin Cancer Res 10:17(5907-18)2004 Sep 1

15302702. Ahmed Z, Marshall MB, Kucharczuk JC, Kaiser LR, Shrager JB, Lung cancer in transplant recipients: a single-institution experience. Arch Surg 139:8(902-6)2004 Aug

15063302. Brinster CJ, Singhal S, Lee L, Marshall MB, Kaiser LR, Kucharczuk JC, Evolving options in the management of esophageal perforation. Ann Thorac Surg 77:4(1475-83)2004 Apr

15063298. Marshall MB, Kaiser LR, Kucharczuk JC, Simple technique for maximal thoracic muscle harvest. Ann Thorac Surg 77:4(1465-6)2004 Apr

14752422. Kruklitis RJ, Singhal S, Delong P, Kapoor V, Sterman DH, Kaiser LR, Albelda SM, Immuno-gene therapy with interferon-beta before surgical debulking delays recurrence and improves survival in a murine model of malignant mesothelioma. J Thorac Cardiovasc Surg 127:1(123-30)2004 Jan

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