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Ashokkumar Jain, MD

Professor, Surgery

Telephone:  215-707-3626

Email: ashokkumar.jain@tuhs.temple.edu

Department of Surgery, Section of Abdominal Organ Transplantation

Undergraduate degree, Hazarimal Somani College, Bombay, India, 1967

 

MD, Topiwala National Medical School, Bombay, India, 1972

 

Rotating Internship, Medicine, Surgery, OB/GYN, Preventive Medicine, Topiwala National Medical School, Bombay, India, 1967-1972

 

Transplant Fellow/Clinical Registrar, Liver and Renal Transplantation, Queen Elizabeth Hospital, Birmingham, England, 1985 -1986

 

Clinical Transplant Research Fellow, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 1989 - 1990

 

Clinical Transplant Fellow, Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 1990 - 1992

 

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Liver transplantation

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Fellow, American College of Surgery, 2003

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• Member of British Transplantation Society, 1986
• Member of International Transplantation Society, 1992
• Member of American Society of Transplant Surgeons, 1993
• Member of American Society of Transplant Physicians, 1996
• Member of American Association for Study of Liver Diseases, 1996
• Member of the International Liver Transplantation Society, 1997
• Corresponding Member European Association for the Study of Liver Diseases, 1998
• Member of the International Pediatric Transplantation Society, 2001
• Member of the International Islet Transplant Registry, 2002
• Member of Central Surgical Association, 2003
• Honorary of Life Time Member International Transplantation Nurses Society (Pittsburgh Chapter)
• Fellow American College of Surgeons, 2003
• Editorial Board for Liver Transplantation, 2003
• Editorial Board for Clinical and Experimental Transplantation, 2005
• Chief Medical Advisor American Liver Foundation, Western NY Chapter, 2003
• European Society for Organ Transplantation, 2004
  

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• Should small for size hepatic allograft be managed differently in adult
  to adult live donor liver transplantation?

• Algorithmic approach to management of acute cellular rejection and
  recurrent hepatic C in post live transplant recipients

• Long-term results of tacrolimus in orthotopic liver transplant

• Kinetics of IV and PO Mycophenolate Mofetil in living donor and deceased
  donor liver transplantation with tacrolimus

• Drug interactions, immunosuppressant with other drugs including HAART
  agents

• De novo cancers after liver transplant

• Post-transplant lymphoproliferative disorder

• Pregnancy after transplantation

• Ribavirin dose concentration profile in relation to renal dysfunction in
  post liver transplant HCV positive patients

• Role of Rituximab for post transplant lymphoproliferative disorder

• Pulmonary function after liver transplant in patients with alpha 1
  anti-trypsin deficiency

• Role of immunohistochemical markers to distinguish recurrent hepatitis C viral infection and acute rejection in post-transplant patients

• In-vivo and In-vitro immunological markers of immunosuppression, and
  dose adjustment based on immunological index and equivalence of various drugs

• Phosphorylation of Ribavirin

• Study of bioequivalence of different forms of Valganciclovir in post
  transplant patients

• Evidence of under diagnosis of hemochromatosis requiring liver
  transplantation in female compared to male patients
  

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

19877215. Jain A, Nemitz P, Sharma R, Sheikh B, Safadjou S, Vetter M, Brayan L, Batzold P, Kashyap R, Orloff M, Incidence of abdominal wall numbness post-liver transplantation and its complications. Liver Transpl 15:11(1488-92)2009 Nov

19790151. Kashyap R, Ryan C, Sharma R, Maloo MK, Safadjou S, Graham M, Tretheway D, Jain A, Orloff M, Liver grafts from donors with central nervous system tumors: a single-center perspective. Liver Transpl 15:10(1204-8)2009 Oct

19741469. Jain A, Fiaz O, Sheikh B, Sharma R, Safadjou S, Kashyap R, Bryan L, Batzold P, Orloff M, Recurrent nonhepatic and de novo malignancies after liver transplantation. Transplantation 88:5(706-10)2009 Sep 15

19476787. Choi DX, Jain AB, Orloff MS, Utility of transjugular intrahepatic portosystemic shunts in liver-transplant recipients. J Am Coll Surg 208:4(539-46)2009 Apr

19430850. Kashyap R, Mantry P, Sharma R, Maloo MK, Safadjou S, Qi Y, Jain A, Maliakkal B, Ryan C, Orloff M, Comparative analysis of outcomes in living and deceased donor liver transplants for primary sclerosing cholangitis. J Gastrointest Surg 13:8(1480-6)2009 Aug

19239480. Jain A, Sharma R, Ryan C, Safadjou S, Kashyap R, Mantry P, Maliakkal B, Orloff M, Response to antiviral therapy in liver transplant recipients with recurrent hepatitis C viral infection: a single center experience. Clin Transplant :()2009 Feb 20

18551061. Kashyap R, Bozorgzadeh A, Abt P, Tsoulfas G, Maloo M, Sharma R, Patel S, Dombroski D, Mantry P, Safadjou S, Jain A, Orloff M, Stratifying risk of biliary complications in adult living donor liver transplantation by magnetic resonance cholangiography. Transplantation 85:11(1569-72)2008 Jun 15

18440919. Jain A, Venkataramanan R, Sharma R, Kwong T, Abt P, Orloff M, Kashyap R, Tsoulfas G, Bozorgzadeh A, Pharmacokinetics of mycophenolic acid in live donor liver transplant patients vs deceased donor liver transplant patients. J Clin Pharmacol 48:5(547-52)2008 May

18347535. Patel S, Cassuto J, Orloff M, Tsoulfas G, Zand M, Kashyap R, Jain A, Bozorgzadeh A, Abt P, Minimizing morbidity of organ donation: analysis of factors for perioperative complications after living-donor nephrectomy in the United States. Transplantation 85:4(561-5)2008 Feb 27

18347534. Jain A, Venkataramanan R, Sharma R, Kwong T, Orloff M, Abt P, Kashyap R, Tsoulfas G, Batzold P, Williamson M, Bozorgzadeh A, Pharmacokinetics of tacrolimus in living donor liver transplant and deceased donor liver transplant recipients. Transplantation 85:4(554-60)2008 Feb 27

18236395. Jain A, Sharma R, Ryan C, Tsoulfas G, Orloff M, Abt P, Kashyap R, Batzold P, Sauberman L, Safadjou S, Graham M, Bozorgzadeh A, Potential immunological advantage of intravenous mycophenolate mofetil with tacrolimus and steroids in primary deceased donor liver transplantation and live donor liver transplantation without antibody induction. Liver Transpl 14:2(202-9)2008 Feb

18034554. Mazariegos GV, Salzedas AA, Zavatsky J, Sindhi R, Parizhskaya M, McGhee W, Jain A, Reyes J, Long term management of liver transplant rejection in children. BioDrugs 14:1(31-48)2000 Jul

17845568. Patel S, Orloff M, Tsoulfas G, Kashyap R, Jain A, Bozorgzadeh A, Abt P, Living-donor liver transplantation in the United States: identifying donors at risk for perioperative complications. Am J Transplant 7:10(2344-9)2007 Oct

17539001. Bozorgzadeh A, Orloff M, Abt P, Tsoulfas G, Younan D, Kashyap R, Jain A, Mantry P, Maliakkal B, Khorana A, Schwartz S, Survival outcomes in liver transplantation for hepatocellular carcinoma, comparing impact of hepatitis C versus other etiology of cirrhosis. Liver Transpl 13:6(807-13)2007 Jun

17538999. Jain A, Venkataramanan R, Kwong T, Mohanka R, Orloff M, Abt P, Kashyap R, Tsoulfas G, Mack C, Williamson M, Batzold P, Bozorgzadeh A, Pharmacokinetics of mycophenolic acid in liver transplant patients after intravenous and oral administration of mycophenolate mofetil. Liver Transpl 13:6(791-6)2007 Jun

17238856. Jain A, Orloff M, Abt P, Kashyap R, Mantry P, Bozorgzadeh A, Postoperative impact of intraoperative biochemical changes at the completion of parenchymal division in living-donor liver transplantation. Exp Clin Transplant 4:2(544-8)2006 Dec

17198264. Abt P, Kashyap R, Orloff M, Jain A, Tsoulfas G, Bozorgzadeh A, Olthoff K, Pediatric liver and kidney transplantation with allografts from DCD donors: A review of UNOS data. Transplantation 82:12(1708-11)2006 Dec 27

17062005. de Vera ME, Dvorchik I, Tom K, Eghtesad B, Thai N, Shakil O, Marcos A, Demetris A, Jain A, Fung JJ, Ragni MV, Survival of liver transplant patients coinfected with HIV and HCV is adversely impacted by recurrent hepatitis C. Am J Transplant 6:12(2983-93)2006 Dec

16968489. Jain A, Ryan C, Mohanka R, Orloff M, Abt P, Romano J, Bryan L, Batzold P, Mantry P, Bozorgzadeh A, Characterization of CD4, CD8, CD56 positive lymphocytes and C4d deposits to distinguish acute cellular rejection from recurrent hepatitis C in post-liver transplant biopsies. Clin Transplant 20:5(624-33)2006 Sep-Oct

16827647. Jain A, Menegus M, Mohanka R, Orloff M, Abt P, Mantry P, Bozorgzadeh A, HCV antibody quantitative levels in liver transplant patients: do they have any relevance in clinical practice? Exp Clin Transplant 4:1(475-80)2006 Jun

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