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Enrique Hernandez, MD

Enrique Hernandez, MD


Abraham Roth Professor and Chair, Department of Obstetrics, Gynecology and Reproductive Sciences

Section Chief, Gynecologic Oncology

Professor, Pathology

Telephone:  215-707-3002

Email: ehernand@temple.edu


Department of Obstetrics, Gynecology and Reproductive Sciences

Department of Pathology and Laboratory Medicine


Educational Background:


Undergraduate degree, University of Puerto Rico, San Juan, PR, 1973


MD, University of Puerto Rico School of Medicine, San Juan, PR, 1977


Internship, The Johns Hopkins Hospital, Baltimore, MD, 1977-1978


Residency (OB-GYN), The Johns Hopkins Hospital, Baltimore, MD, 1978-1981


Fellowship (Gynecologic Oncology), The Johns Hopkins Hospital, Baltimore, MD, 1981-1983


Research in Radiation Biology, The Johns Hopkins Hospital, Baltimore, MD, 1981-1983


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clinical Interests:



  • Gynecologic oncology


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board certifications:


  • American Board of Obstetrics and Gynecology, 1984
  • American Board of Obstetrics and Gynecology (Gynecologic Oncology), 1985

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professional affiliations:

  • Regent, Board of Regents, American College of Surgeons
  • Board Member, National Board of Directors, American Cancer Society
  • Board Member, American Cancer Society, East Central Division
  • Trustee, Board of Trustees, Pennsylvania Medical Society
  • Past Second Vice-President, American Cancer Society
  • Past President, Philadelphia County Medical Society
  • Past President, Mid-Atlantic Gynecologic Oncology Society
  • Past President, Obstetrical Society of Philadelphia
  • Past President, Metropolitan Philadelphia Chapter, American College of Surgeons
  • Past President, Society of Ibero-American Medical Professionals
  • Past President, American Cancer Society, Pennsylvania Division
  • Past Board Member, American Cancer Society, Pennsylvania Division
  • Past Governor, American College of Surgeons
  • Past Chair, By-Laws Committee, Society of Gynecologic Oncologists


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research interests:


  • Clinical trials on gynecologic malignancies
  • Evaluation and management of abnormal PAP smears
  • Cervical cancer and its precursors

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BOOKS or book chapters:


Hernandez E.  Endometrial carcinoma (chapter 45) In:  Beiber E, Sanfilippo J, Horowitz I (eds).  Clinical Gynecology, Churchill Livingstone (Elsevier), 2006, 665-675.


Hernandez E, Atkinson B (eds).  Clinical Gynecologic Pathology (Chinese translation), Philadelphia, W.B. Saunders, 1998.


Spence MR, Hernandez E.  Benign conditions of the vagina and cervix.  In: Hernandez E, Atkinson BF (eds), Clinical Gynecologic Pathology.  Philadelphia, W.B. Saunders, 1995, 91-128.


Heller PB, Hernandez E, Atkinson BF.  Malignant neoplasms of the cervix and vagina.  In:  Hernandez E, Atkinson BF (eds), Clinical Gynecologic Pathology.  Philadelphia, W.B. Saunders, 1995, 175-222.


Balsara G, Hernandez E.  The ovary: normal, physiologic changes, endometriosis, and metastatic tumors.  In:  Hernandez E, Atkinson BF (eds), Clinical Gynecologic Pathology.  Philadelphia, W.B. Saunders, 1995, 403-422.


Trimble CL, Trimble EL, Hernandez E.  Tumors of the ovarian stroma.  In:  Hernandez E, Atkinson BF (eds), Clinical Gynecologic Pathology.  Philadelphia, W.B. Saunders, 1995, 501-526.


Hernandez E, Balsara G.  Gestational trophoblastic disease.  In:  Hernandez E, Atkinson BF (eds), Clinical Gynecologic Pathology.  Philadelphia, W.B. Saunders, 1995, 527-552.


Hernandez E, Rosenshein NB.  Manual of Gynecologic Oncology, New York, Churchill Livingstone, 1989.


Rosenshein NB, Hernandez E, Rosenblatt K.  Risk factors for ovarian cancer.  In:  Gold E (ed), Changing Risks for Disease in Women:  An Epidemiologic Approach.  Lexington, DC Heath and Co, 1984, pp 221-231.


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selected publications:


Manne S, Kashy D, Rubin S, Hernandez E, Bergman C. Therapist and patient perceptions of alliance and progress in psychological therapy for women diagnosed with gynecological cancers.  J Consulting Clin Psychol 2012;80:800-810.


Uppal S, Hernandez E, Dutta M, Dandolu V, Rose SL, Hartenbach E. Prolonged postoperative venous thromboembolism prophylaxis is cost-effective in advanced ovarian cancer patients. Gynecol Oncol 2012;127:631-637.


Manne S, Winkel G, Zaider T, Rubin S, Hernandez E, Bergman C. Therapy processes and outcomes of psychological interventions for women diagnosed with gynecological cancers: a test of the generic process model of psychotherapy. J Consulting Clin Psychol 2010;78:236-248.


Manne S, Rini C, Rubin S, Rosenblum N, Bergman C, Edelson M, Hernandez E, Carlson J, Rocereto T.  Long-term trajectories of psychological adaptation among women diagnosed with gynecological cancers.  Psychosomatic Med 2008;70:677-687.


Manne S, Winkel G, Rubin S, Edelson M, Rosenblum N, Bergman C, Hernandez E, Carlson J, Rocetero T.  Mediators of a coping and communication-enhancing intervention and a supportive counseling among women diagnosed with gynecological cancers.  J Consulting and  Clin Psychol 2008;76:1034-1045.


Manne S, Rubin S, Edelson M, Rosenblum N, Bergman C. Hernandez E, Carlson J, Rocereto T, Winkel G.  Coping and communication enhancing intervention versus supportive counseling for women diagnosed with gynecological cancers.  J Consulting and Clin Psychol 2007;75:615-28.


Zhang Z, Borecki I, Nguyen L, MaD, Smith K, Huettner PC, Muthc D, Hezog TJ, Gibb RK, Powell MA, Grigsby PW, Massad LS, Hernandez E, Judson PL, Swisher Em, Crowder S, Li J, Gerhard DS, Rader JS.  CD83 gene polymorphism increase susceptibility to human invasive cervical cancer.  Cancer Res  2007;67:11202-11208.


Dandolu V, Harmanli OH, Grotegut C, Turner T, Hernandez E, Grody MT.  Long-term anatomic and functional outcome following sacrospinous fixation using comprehensive pelvic floor questionnaires.  J Pelvic Med Surg 2007;13:177-180.


Harmanli O, Bevilacqua SA, Dandolu V, Chatwani AJ, Hernandez E:  Adenomyosis interferes with accurate ultrasonographic detection of uterine leiomyomas.  Arch Gynecol Obstet 2005:273:146-149.


Norton TR, Manne SL, Rubin S, Hernandez E, Carlson J, Bergman C, Rosenblum N,  Ovarian cancer patients' psychological distress:  The role of physical impairment, unsupportive family and friend behaviors, perceived control, and self-esteem.  Health Psychology 24:(143-152)2005.


Norton TR, Manne SL, Rubin S, Carlson J, Hernandez E, Edelson MI, Rosenblum N, Warshal D, Bergman C, Prevalence and predictors of psychological distress among women with ovarian cancer. J Clin Oncol 22:(919-926)2004.


Hernandez E, Donohue KA, Anderson LL, Heller PB, Stehman FB, The significance of thrombocytosis in patients with advanced cervical carcinoma: A Gynecologic Oncology Group study. Gynecol Oncol 78:(137-142)2000.


Cheng RF, Hernandez E, Anderson L, Heller P, Shank R, The clinical significance of a cytologic diagnosis of atypical glandular cells of undetermined significance. J Reprod Med 44:(922-928)1999.


Corn BF, Micaily B, Dunton CJ, Valicenti RK, Anderson L, Hernandez E, Concomitant irradiation and dose-escalating carboplatin for locally advanced carcinoma of the uterine cervix: An updated report. Am J Clin Oncol 21:(31-35)1998.


Simmons JR, Anderson L, Hernandez E, Heller PB, Loop electrosurgical excision procedure as an alternative to cold-knife conization in the evacuation of cervical neoplasia. J Repro Med 43:(1007-1010)1998.


Eisenberger D, Hernandez E, Tener T, Atkinson B, Order of endocervical and ectocervical cytologic sampling and the quality of the Papanicolaou Smear. Obstet Gynecol 90:(755-758)1997.


Miller SM, Siejak KK, Schoeder CM, Lerman C, Hernandez E, Helm CW, Enhancing adherence following abnormal Pap smears among low-income minority women: A preventive telephone counseling strategy. J Natl Cancer Inst 89:(703-708)1997.


Corn BW, Shaktman BD, Lanciano RM, Hogan WM, Carter JR, Anderson L, Heller PB, Hernandez E,: Intra- and perioperative complications associated with tandem and ovoid colpostat application of cervix cancer. Gynecol Oncol 64:(224-229)1997.


Corn BW, Hernandez E, Anderson L, Fein DA, Dunton CJ, Heller P, Phase I study of concomitant irradiation and Carboplatin for locally advanced carcinoma of the uterine cervix. An interim report. Am J Clin Oncol 19:(317-321)1996.


Smith-Levitin M, Hernandez E, Anderson L, Heller P, The safety, efficacy, and cost of three cervical cytology sampling devices in a prenatal clinic. J Repro Med 41:(749-753)1996.


Gonzalez D, Hernandez E, Anderson L, Heller P, Atkinson BF, Clinical significance of a cervical cytologic diagnosis of atypical squamous cells of undetermined significance favor reactive process or low-grade squamous intraepithelial lesion. J Repro Med 41:(719-723)1996.


Hernandez E, Heller PB, Whitney C, Diana K, Delgado G, Thrombocytosis in surgically treated Stage I-B squamous cell cervical carcinoma. Gynecol Oncol 55:(328-332)1994.


Nathan F, Hernandez E, Dunton CJ, Treat J, Switaliska HI, Joseph RR, Tuszynski GP, Plasma thrombospondin levels in patients with gynecologic malignancies. Cancer 73:(2853-2858)1994.


Harrison DD, Hernandez E, Dunton CJ, A cost comparison of endocervical brush versus cotton swab for obtaining cervical smears in a clinic setting. J Reprod Med 38:(285-288)1993.


Zangwill BC, Balsara G, Dunton C, Varello M, Rebane BA, Hernandez E, Atkinson B, Ovarian adenocarcinoma heterogeneity as demonstrated by DNA ploidy. Cancer 71:(2261-2267)1993.


Hernandez E, Lavine M, Dunton CJ, Gracely E, Parker J, Poor prognosis associated with thrombocytosis in patients with cervical cancer.  Cancer 69:(2975-2977)1992.


Dunton CJ, Balsara G, McFarland M, Hernandez E, Uterine papillary serous carcinoma: A review. Obstet Gynecol Surv 46:(97-102)1991.


Ramirez EJ, Hernandez E, Miyazawa K, Cervical conization findings in women with dysplastic cervical cytology and normal colposcopy. J Reprod Med 35:(359-361)1990. (Abstracted in 1991 Yearbook of Obstetrics and Gynecology)


Andrews S, Hernandez E, Miyazawa K, Paired Papanicolaou smears in the evaluation of atypical squamous cells. Obstet Gynecol 73:(747)l989.


Ridgley R, Hernandez E, Cruz C, Miyazawa K, Abnormal Papanicolaou smears following previous cytology of atypical squamous cells. J Reprod Med 33:(285-288)1988.


Presley JJ, Hernandez E, Mudafort E, Miyazawa K, Endometrial and endocervical curettage at the time of cervical conization. J Reprod Med 32:(99-l02)l987.


Davis G, Hernandez E, Davis J, Miyazawa K, Atypical squamous cells in Papanicolaou smears. Obstet Gynecol 69:(43-46)l987.


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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

26335312. Lee M, Miller SM, Wen KY, Hui SK, Roussi P, Hernandez E, Cognitive-behavioral intervention to promote smoking cessation for pregnant and postpartum inner city women. J Behav Med 38:6(932-43)2015 Dec

25431594. Diaz J, Yu D, Micaily B, Ferriss JS, Hernandez E, Radiation therapy with concurrent chemotherapy for locally advanced cervical carcinoma: outcome analysis with emphasis on the impact of treatment duration on outcome. Obstet Gynecol Int 2014:(214351)2014

25099776. Wen KY, Miller SM, Roussi P, Belton TD, Baman J, Kilby L, Hernandez E, A content analysis of self-reported barriers and facilitators to preventing postpartum smoking relapse among a sample of current and former smokers in an underserved population. Health Educ Res 30:1(140-51)2015 Feb

24949539. Igwe E, Hernandez E, Rose S, Uppal S, Resident participation in laparoscopic hysterectomy: impact of trainee involvement on operative times and surgical outcomes. Am J Obstet Gynecol 211:5(484.e1-7)2014 Nov

24718518. Hui SK, Miller SM, Wen KY, Fang Z, Li T, Buzaglo J, Hernandez E, Psychosocial barriers to follow-up adherence after an abnormal cervical cytology test result among low-income, inner-city women. J Prim Care Community Health 5:4(234-41)2014 Oct

24698804. Wen KY, Miller SM, Kilby L, Fleisher L, Belton TD, Roy G, Hernandez E, Preventing postpartum smoking relapse among inner city women: development of a theory-based and evidence-guided text messaging intervention. JMIR Res Protoc 3:2(e20)2014 Apr 3

24007767. Miller SM, Hui SK, Wen KY, Scarpato J, Zhu F, Buzaglo J, Hernandez EE, Tailored telephone counseling to improve adherence to follow-up regimens after an abnormal pap smear among minority, underserved women. Patient Educ Couns 93:3(488-95)2013 Dec

23091988. Diaz J, Thomas MB, Paz-Pabon C, Hernandez E, Methotrexate on a 21-day cycle for low-risk gestational trophoblastic neoplasia. J Reprod Med 57:9-10(411-4)2012 Sep-Oct

22503523. Kemmerer E, Hernandez E, Ferriss JS, Valakh V, Miyamoto C, Li S, Micaily B, Use of image-guided stereotactic body radiation therapy in lieu of intracavitary brachytherapy for the treatment of inoperable endometrial neoplasia. Int J Radiat Oncol Biol Phys 85:1(129-35)2013 Jan 1

21811179. Hernandez E, De La Mota J, Thomas MB, Huang Y, Gaughan JP, Wang F, Surgical-pathologic risk factors and immunohistochemical markers of pelvic lymph node metastasis in stage IB1 cervical cancer. J Low Genit Tract Dis 15:4(303-8)2011 Oct

20847943. Hernandez E, Obermair A, Hoskins PJ, Magrina JF, McLellan R, Controversies in the management of endometrial cancer. Obstet Gynecol Int 2010:()2010

20339473. Thomas MB, Dandolu V, Caputo P, Milner R, Hernandez E, Resident education in principles and technique of bowel surgery using an ex-vivo porcine model. Obstet Gynecol Int 2010:(852647)2010

20093903. Uppal S, Harmanli O, Rowland J, Hernandez E, Dandolu V, Resident competency in obstetric anal sphincter laceration repair. Obstet Gynecol 115:2 Pt 1(305-9)2010 Feb

20018356. De La Mota J, Thomas MB, Micaily B, Espaillat-Rijo L, Hernandez E, Polyostotic fibrous dysplasia mimicking bone metastases in a patient with advanced-stage cervical cancer. Gynecol Oncol 116:3(584-5)2010 Mar

19601709. Hernandez E, Ganly P, Charu V, Dibenedetto J, Tomita D, Lillie T, Taylor K, Randomized, double-blind, placebo-controlled trial of every-3-week darbepoetin alfa 300 micrograms for treatment of chemotherapy-induced anemia. Curr Med Res Opin 25:9(2109-20)2009 Sep

19079625. Draganova-Tacheva RA, Khurana JS, Huang Y, Hernandez E, Zhang X, Large cell neuroendocrine carcinoma of the ovary associated with serous carcinoma with mucin production: a case report and literature review. Int J Clin Exp Pathol 2:3(304-9)2009

18503573. Geifman-Holtzman O, Grotegut CA, Gaughan JP, Holtzman EJ, Floro C, Hernandez E, Noninvasive fetal RhCE genotyping from maternal blood. BJOG 116:2(144-51)2009 Jan

17980205. Newmark J, Dandolu V, Milner R, Grewal H, Harbison S, Hernandez E, Correlating virtual reality and box trainer tasks in the assessment of laparoscopic surgical skills. Am J Obstet Gynecol 197:5(546.e1-4)2007 Nov

17955080. Ramchandani SM, Houck KL, Hernandez E, Gaughan JP, Predicting persistent/recurrent disease in the cervix after excisional biopsy. MedGenMed 9:2(24)2007 Apr 30

17879839. Quintero C, Sasken H, Houck KL, Hernandez E, Angiomyofibroblastoma of the retroperitoneum: a case report. J Reprod Med 52:8(741-4)2007 Aug

17583247. Rojas-Espaillat L, Houck KL, Hernandez E, Berkowitz RS, Fertility-sparing surgery for persistent gestational trophoblastic neoplasia in the myometrium: a case report. J Reprod Med 52:5(431-4)2007 May

17415117. Han X, Shen T, Rojas-Espaillat LA, Hernandez E, Giant cell fibroblastoma of the vulva at the site of a previous fibroepithelial stromal polyp: a case report. J Low Genit Tract Dis 11:2(112-7)2007 Apr

17001555. Dandolu V, Jain NJ, Hernandez E, Kruse L, Shoulder dystocia at noninstrumental vaginal delivery. Am J Perinatol 23:7(439-44)2006 Oct

16482772. Brummitt K, Harmanli OH, Gaughan J, Dandolu V, Chatwani AJ, Hernandez E, Gynecologists' attitudes toward hysterectomy: is the sex of the clinician a factor? J Reprod Med 51:1(21-5)2006 Jan

16390789. Dandolu V, Lawrence L, Gaughan JP, Grotegut C, Harmanli OH, Jaspan D, Hernandez E, Trends in the rate of shoulder dystocia over two decades. J Matern Fetal Neonatal Med 18:5(305-10)2005 Nov

16038891. Pappas J, Jung WJ, Barda AK, Lin WL, Fincke JE, Purev E, Radu M, Gaughan J, Helm CW, Hernandez E, Freedman RS, Platsoucas CD, Substantial proportions of identical beta-chain T-cell receptor transcripts are present in epithelial ovarian carcinoma tumors. Cell Immunol 234:2(81-101)2005 Apr

15809773. Dandolu V, Chatwani A, Harmanli O, Floro C, Gaughan JP, Hernandez E, Risk factors for obstetrical anal sphincter lacerations. Int Urogynecol J Pelvic Floor Dysfunct 16:4(304-7)2005 Jul-Aug

15802413. Dandolu V, Gaughan JP, Chatwani AJ, Harmanli O, Mabine B, Hernandez E, Risk of recurrence of anal sphincter lacerations. Obstet Gynecol 105:4(831-5)2005 Apr

15047216. Kaur TB, Shen T, Gaughan J, Thompson J, Houck KL, Richardson M, Hernandez E, Premalignant lesions in the contralateral ovary of women with unilateral ovarian carcinoma. Gynecol Oncol 93:1(69-77)2004 Apr

14677006. Dandolu V, Mathai E, Chatwani A, Harmanli O, Pontari M, Hernandez E, Accuracy of cystoscopy in the diagnosis of ureteral injury in benign gynecologic surgery. Int Urogynecol J Pelvic Floor Dysfunct 14:6(427-31)2003 Dec

12902900. Davis-Perry S, Hernandez E, Houck KL, Shank R, Melphalan for the treatment of patients with recurrent epithelial ovarian cancer. Am J Clin Oncol 26:4(429-33)2003 Aug

11766149. Hernandez E, Endometrial adenocarcinoma: a primer for the generalist. Obstet Gynecol Clin North Am 28:4(743-57)2001 Dec

11531302. Oh C, Kendler A, Hernandez E, Ovarian endodermal sinus tumor in a postmenopausal woman. Gynecol Oncol 82:2(392-4)2001 Aug

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additional information:



Listed in Guide to America's Top Obstetricians and Gynecologists, Consumer's Research Council of America



Listed in Consumer's Checkbook of Top Doctors (2007)


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