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John Gaughan, MS, PhD, MBA


Emeritus Associate Professor, Physiology

Telephone:  215-707-2984

Fax:  215-707-0170

Office: Old Medical School Room 226

Email: jgaughan@temple.edu


Department of Physiology


Educational Background:


BS, MS, Biology, 1969-1972

Villanova University

Villanova, PA


MS, Applied Statistics, 1979

Villanova University

Villanova, PA


MBA, Finance, 1983

Temple University

Philadelphia, PA


PhD, Exercise Physiology, 1995

Temple University

Philadelphia, PA


Postdoctoral Fellowship, Electrophysiology, 1996

Temple University

Philadelphia, PA


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Research Interests:


  • Statistical modeling of action potentials and membrane currents in cardiac myocytes.
  • Electrophysiology of excitation-contraction coupling as it relates to the development of cardiac arrhythmias.
  • Electrophysiology of cardiac stem cells.

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

26218696. Smith BP, Goldberg AJ, Gaughan JP, Seamon MJ, A comparison of Injury Severity Score and New Injury Severity Score after penetrating trauma: A prospective analysis. J Trauma Acute Care Surg 79:2(269-74)2015 Aug

26207355. Reichenbach ZW, Li H, Gaughan JP, Elliott M, Tuma R, IV and IP administration of rhodamine in visualization of WBC-BBB interactions in cerebral vessels. Microsc Res Tech :()2015 Jul 24

26149842. Koutroulis I, Pyle T, Kopylov D, Little A, Gaughan J, Kratimenos P, The Association Between Bathing Habits and Severity of Atopic Dermatitis in Children. Clin Pediatr (Phila) :()2015 Jul 6

25999250. Taghavi S, Ambur V, Jayarajan SN, Gaughan J, Toyoda Y, Dauer E, Sjoholm LO, Pathak A, Santora T, Goldberg AJ, Rappold J, Postoperative outcomes with cholecystectomy in lung transplant recipients. Surgery 158:2(373-8)2015 Aug

25913167. Friedman A, Balfour S, Reinus W, Gaughan J, Emergency Department Extremity Radiographs in the Setting of Pain Without Trauma: Are They Worth the Pain? J Emerg Med 49:2(152-8)2015 Aug

25707549. Tosti R, Trionfo A, Gaughan J, Ilyas AM, Risk factors associated with clindamycin-resistant, methicillin-resistant Staphylococcus aureus in hand abscesses. J Hand Surg Am 40:4(673-6)2015 Apr

25694925. Lavelle WF, Ranade A, Samdani AF, Gaughan JP, D'Andrea LP, Betz RR, Inter- and intra-observer reliability of measurement of pedicle screw breach assessed by postoperative CT scans. Int J Spine Surg 8:()2014

25662159. Koutroulis I, Magnelli L, Gaughan J, Weiner E, Kratimenos P, Atopic dermatitis is more severe in children over the age of two who have an increased body mass index. Acta Paediatr 104:7(713-7)2015 Jul

25232077. Tosti R, Samuelsen BT, Bender S, Fowler JR, Gaughan J, Schaffer AA, Ilyas AM, Emerging multidrug resistance of methicillin-resistant Staphylococcus aureus in hand infections. J Bone Joint Surg Am 96:18(1535-40)2014 Sep 17

25128547. Lu S, White JV, Lin WL, Zhang X, Solomides C, Evans K, Ntaoula N, Nwaneshiudu I, Gaughan J, Monos DS, Oleszak EL, Platsoucas CD, Response to comment on "aneurysmal lesions of patients with abdominal aortic aneurysm contain clonally expanded T cells". J Immunol 193:5(2041)2014 Sep 1

24977749. Taghavi S, Jayarajan SN, Ferrer LM, Vora H, McKee C, Milner RE, Gaughan JP, Dujon J, Sjoholm LO, Pathak A, Rappold JF, Santora TA, Houser SR, Goldberg AJ, "Permissive hypoventilation" in a swine model of hemorrhagic shock. J Trauma Acute Care Surg 77:1(14-9)2014 Jul

24811931. Singla S, Papavasiliou P, Powers B, Gaughan J, von Mehren M, Watson JC, Farma JM, Challenges in the treatment of angiosarcoma: a single institution experience. Am J Surg 208:2(254-9)2014 Aug

24752442. Lu S, White JV, Lin WL, Zhang X, Solomides C, Evans K, Ntaoula N, Nwaneshiudu I, Gaughan J, Monos DS, Oleszak EL, Platsoucas CD, Aneurysmal lesions of patients with abdominal aortic aneurysm contain clonally expanded T cells. J Immunol 192:10(4897-912)2014 May 15

24636027. Tosti R, Iorio J, Fowler JR, Gaughan J, Thoder JJ, Schaffer AA, Povidone-iodine soaks for hand abscesses: a prospective randomized trial. J Hand Surg Am 39:5(962-5)2014 May

24634423. Koutroulis I, Petrova K, Kratimenos P, Gaughan J, Frequency of bathing in the management of atopic dermatitis: to bathe or not to bathe? Clin Pediatr (Phila) 53:7(677-81)2014 Jun

24426861. Walsh KP, Fowler JR, Chen O, Gaughan JP, Ali S, Rehman M, Rehman S, The validity and reliability of preoperative radiographic canal diameter measurements of the femur. HSS J 9:2(150-6)2013 Jul

24421464. Perez ME, Bcps, Varga LI, Bcps, Rose C, Bcps, Gaughan JP, Comparison of the efficacy and safety of two different insulin infusion protocols in the medical intensive care unit. Hosp Pharm 48:3(213-8)2013 Mar

24401498. Taghavi S, Vora HP, Jayarajan SN, Gaughan JP, Pathak AS, Santora TA, Goldberg AJ, Prehospital intubation does not decrease complications in the penetrating trauma patient. Am Surg 80:1(9-14)2014 Jan

24224424. Taghavi S, Clark R, Jayarajan SN, Gaughan J, Brann SH, Mangi AA, Surgical management of tricuspid valve endocarditis in systemically infected patients. J Heart Valve Dis 22:4(578-83)2013 Jul

24132665. Keller DS, Thomay AA, Gaughan J, Olszanski A, Wu H, Berger AC, Farma JM, Outcomes in patients with mucosal melanomas. J Surg Oncol 108:8(516-20)2013 Dec

23968757. Taghavi S, Ward C, Jayarajan SN, Gaughan J, Wilson LM, Mangi AA, Surgical technique influences HeartMate II left ventricular assist device thrombosis. Ann Thorac Surg 96:4(1259-65)2013 Oct

23928440. Khocht A, Seyedain M, Hardan S, Gaughan J, Suzuki JB, Salivary thiol levels and periodontal parameters assessed with a chromogenic strip. Gen Dent 61:5(50-4)2013 Aug

23824763. Robinson RH, Meissler JJ, Breslow-Deckman JM, Gaughan J, Adler MW, Eisenstein TK, Cannabinoids inhibit T-cells via cannabinoid receptor 2 in an in vitro assay for graft rejection, the mixed lymphocyte reaction. J Neuroimmune Pharmacol 8:5(1239-50)2013 Dec

23610668. Fowler JR, Kleiner MT, Das R, Gaughan JP, Rehman S, Assisted closure of fasciotomy wounds: A descriptive series and caution in patients with vascular injury. Bone Joint Res 1:3(31-5)2012 Mar

23609274. Taghavi S, Jayarajan SN, Khoche S, Duran JM, Cruz-Schiavone GE, Milner RE, Holt-Bright L, Gaughan JP, Rappold JF, Sjoholm LO, Dujon J, Pathak A, Santora TA, Houser SR, Goldberg AJ, Examining prehospital intubation for penetrating trauma in a swine hemorrhagic shock model. J Trauma Acute Care Surg 74:5(1246-51)2013 May

23358845. Keller DS, Parkman HP, Boucek DO, Sankineni A, Meilahn JE, Gaughan JP, Harbison S, Surgical outcomes after gastric electric stimulator placement for refractory gastroparesis. J Gastrointest Surg 17:4(620-6)2013 Apr

22991661. Singla S, Guenthart BA, May L, Gaughan J, Meilahn JE, Intussusception after laparoscopic gastric bypass surgery: an underrecognized complication. Minim Invasive Surg 2012:(464853)2012

22966227. Del Vecchio MT, Doerr LE, Gaughan JP, The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis. Interdiscip Perspect Infect Dis 2012:(585901)2012

22939037. Taghavi S, Wilson LM, Brann SH, Gaughan J, Mangi AA, Cardiac transplantation can be safely performed with low donor-to-recipient body weight ratios. J Card Fail 18:9(688-93)2012 Sep

22927150. Rehman S, Salari N, Codjoe P, Rehman M, Gaughan J, Gunshot femoral fractures with vascular injury: a retrospective analysis. Orthop Surg 4:3(166-71)2012 Aug

22907951. Lee IJ, Hilliard B, Swami A, Madara JC, Rao S, Patel T, Gaughan JP, Lee J, Gadegbeku CA, Choi ET, Cohen PL, Growth arrest-specific gene 6 (Gas6) levels are elevated in patients with chronic renal failure. Nephrol Dial Transplant 27:11(4166-72)2012 Nov

22846936. Taghavi S, Duran JM, Jayarajan S, Cruz-Schiavone GE, Milner RE, Gaughan JP, Sjoholm LO, Pathak A, Santora TA, Houser SR, Goldberg AJ, Still making the case against prehospital intubation: a rat hemorrhagic shock model. J Trauma Acute Care Surg 73:2(332-7; discussion 337)2012 Aug

22828144. Taghavi S, Jayarajan SN, Duran JM, Gaughan JP, Pathak A, Santora TA, Willis AI, Goldberg AJ, Does payer status matter in predicting penetrating trauma outcomes? Surgery 152:2(227-31)2012 Aug

22688145. Parkman HP, Mishra A, Jacobs M, Pathikonda M, Sachdeva P, Gaughan J, Krynetskiy E, Clinical response and side effects of metoclopramide: associations with clinical, demographic, and pharmacogenetic parameters. J Clin Gastroenterol 46:6(494-503)2012 Jul

22686467. Li L, Kueppers F, Hildebrand W, Buchli R, Gaughan J, Elevated soluble HLA II protein levels in patients with alpha-1 antitrypsin deficiency with or without COPD. Exp Lung Res 38:6(302-6)2012 Aug

22512287. Homko CJ, Deeb LC, Rohrbacher K, Mulla W, Mastrogiannis D, Gaughan J, Santamore WP, Bove AA, Impact of a telemedicine system with automated reminders on outcomes in women with gestational diabetes mellitus. Diabetes Technol Ther 14:7(624-9)2012 Jul

22450952. Singla S, Keller D, Thirunavukarasu P, Tamandl D, Gupta S, Gaughan J, Dempsey D, Splenic injury during colonoscopy--a complication that warrants urgent attention. J Gastrointest Surg 16:6(1225-34)2012 Jun

22399851. Garfield JL, Marchetti N, Gaughan JP, Steiner RM, Criner GJ, Total lung capacity by plethysmography and high-resolution computed tomography in COPD. Int J Chron Obstruct Pulmon Dis 7:(119-26)2012

22300927. Barakat N, Mohamed FB, Hunter LN, Shah P, Faro SH, Samdani AF, Finsterbusch J, Betz R, Gaughan J, Mulcahey MJ, Diffusion tensor imaging of the normal pediatric spinal cord using an inner field of view echo-planar imaging sequence. AJNR Am J Neuroradiol 33:6(1127-33)2012 Jun

22230131. Spivack DE, Kelly P, Gaughan JP, van Bemmelen PS, Mapping of superficial extremity veins: normal diameters and trends in a vascular patient-population. Ultrasound Med Biol 38:2(190-4)2012 Feb

22186744. Bohm M, Malik Z, Sebastiano C, Thomas R, Gaughan J, Kelsen S, Richter JE, Mucosal eosinophilia: prevalence and racial/ethnic differences in symptoms and endoscopic findings in adults over 10 years in an urban hospital. J Clin Gastroenterol 46:7(567-74)2012 Aug

22016001. Piposar J, Fowler JR, Gaughan JP, Rehman S, Race may not affect [correct] outcomes in operatively treated tibia fractures. Clin Orthop Relat Res 470:5(1513-7)2012 May

21928415. Andrews G, Lango M, Cohen R, Feigenberg S, Burtness B, Mehra R, Ahmed S, Nicolaou N, Gaughan J, Ridge JA, Nonsurgical management of oropharyngeal, laryngeal, and hypopharyngeal cancer: the Fox Chase Cancer Center experience. Head Neck 33:10(1433-40)2011 Oct

21826405. Breslow JM, Monroy MA, Daly JM, Meissler JJ, Gaughan J, Adler MW, Eisenstein TK, Morphine, but not trauma, sensitizes to systemic Acinetobacter baumannii infection. J Neuroimmune Pharmacol 6:4(551-65)2011 Dec

21811179. Hernandez E, De La Mota J, Thomas MB, Huang Y, Gaughan JP, Wang F, Surgical-pathologic risk factors and immunohistochemical markers of pelvic lymph node metastasis in stage IB1 cervical cancer. J Low Genit Tract Dis 15:4(303-8)2011 Oct

21780848. Fowler JR, Gaughan JP, Boden BP, Pavlov H, Torg JS, The non-surgical and surgical treatment of tarsal navicular stress fractures. Sports Med 41:8(613-9)2011 Aug 1

21629130. Maurer AH, Burshteyn M, Adler LP, Gaughan JP, Steiner RM, Variable cardiac 18FDG patterns seen in oncologic positron emission tomography computed tomography: importance for differentiating normal physiology from cardiac and paracardiac disease. J Thorac Imaging 27:4(263-8)2012 Jul

21576323. Breslow JM, Meissler JJ Jr, Hartzell RR, Spence PB, Truant A, Gaughan J, Eisenstein TK, Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance. Infect Immun 79:8(3317-27)2011 Aug

21573034. Mamary AJ, Kondapaneni S, Vance GB, Gaughan JP, Martin UJ, Criner GJ, Survival in Patients Receiving Prolonged Ventilation: Factors that Influence Outcome. Clin Med Insights Circ Respir Pulm Med 5:(17-26)2011 Apr 25

21513441. Krachman SL, Chatila W, Martin UJ, Permut I, D'Alonzo GE, Gaughan JP, Sternberg AL, Ciccolella D, Criner GJ, Physiologic correlates of sleep quality in severe emphysema. COPD 8:3(182-8)2011 Jun

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