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John Gaughan, MS, PhD, MBA

Emeritus Associate Professor, Physiology

Telephone:  215-707-2984

Fax:  215-707-0170

Office: Old Medical School Room 226

Email: jgaughan@temple.edu

Department of Physiology

BS, MS, Biology, 1969-1972

Villanova University

Villanova, PA

 

MS, Applied Statistics, 1979

Villanova University

Villanova, PA

 

MBA, Finance, 1983

Temple University

Philadelphia, PA

 

PhD, Exercise Physiology, 1995

Temple University

Philadelphia, PA

 

Postdoctoral Fellowship, Electrophysiology, 1996

Temple University

Philadelphia, PA

 

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• Statistical modeling of action potentials and membrane currents in cardiac myocytes.

• Electrophysiology of excitation-contraction coupling as it relates to the development of cardiac arrhythmias.

• Electrophysiology of cardiac stem cells.
  

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

23610668. Fowler JR, Kleiner MT, Das R, Gaughan JP, Rehman S, Assisted closure of fasciotomy wounds: A descriptive series and caution in patients with vascular injury. Bone Joint Res 1:3(31-5)2012 Mar

23609274. Taghavi S, Jayarajan SN, Khoche S, Duran JM, Cruz-Schiavone GE, Milner RE, Holt-Bright L, Gaughan JP, Rappold JF, Sjoholm LO, Dujon J, Pathak A, Santora TA, Houser SR, Goldberg AJ, Examining prehospital intubation for penetrating trauma in a swine hemorrhagic shock model. J Trauma Acute Care Surg 74:5(1246-51)2013 May

23358845. Keller DS, Parkman HP, Boucek DO, Sankineni A, Meilahn JE, Gaughan JP, Harbison S, Surgical outcomes after gastric electric stimulator placement for refractory gastroparesis. J Gastrointest Surg 17:4(620-6)2013 Apr

22991661. Singla S, Guenthart BA, May L, Gaughan J, Meilahn JE, Intussusception after laparoscopic gastric bypass surgery: an underrecognized complication. Minim Invasive Surg 2012:(464853)2012

22966227. Del Vecchio MT, Doerr LE, Gaughan JP, The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis. Interdiscip Perspect Infect Dis 2012:(585901)2012

22939037. Taghavi S, Wilson LM, Brann SH, Gaughan J, Mangi AA, Cardiac transplantation can be safely performed with low donor-to-recipient body weight ratios. J Card Fail 18:9(688-93)2012 Sep

22927150. Rehman S, Salari N, Codjoe P, Rehman M, Gaughan J, Gunshot femoral fractures with vascular injury: a retrospective analysis. Orthop Surg 4:3(166-71)2012 Aug

22907951. Lee IJ, Hilliard B, Swami A, Madara JC, Rao S, Patel T, Gaughan JP, Lee J, Gadegbeku CA, Choi ET, Cohen PL, Growth arrest-specific gene 6 (Gas6) levels are elevated in patients with chronic renal failure. Nephrol Dial Transplant 27:11(4166-72)2012 Nov

22846936. Taghavi S, Duran JM, Jayarajan S, Cruz-Schiavone GE, Milner RE, Gaughan JP, Sjoholm LO, Pathak A, Santora TA, Houser SR, Goldberg AJ, Still making the case against prehospital intubation: a rat hemorrhagic shock model. J Trauma Acute Care Surg 73:2(332-7; discussion 337)2012 Aug

22828144. Taghavi S, Jayarajan SN, Duran JM, Gaughan JP, Pathak A, Santora TA, Willis AI, Goldberg AJ, Does payer status matter in predicting penetrating trauma outcomes? Surgery 152:2(227-31)2012 Aug

22688145. Parkman HP, Mishra A, Jacobs M, Pathikonda M, Sachdeva P, Gaughan J, Krynetskiy E, Clinical response and side effects of metoclopramide: associations with clinical, demographic, and pharmacogenetic parameters. J Clin Gastroenterol 46:6(494-503)2012 Jul

22686467. Li L, Kueppers F, Hildebrand W, Buchli R, Gaughan J, Elevated soluble HLA II protein levels in patients with alpha-1 antitrypsin deficiency with or without COPD. Exp Lung Res 38:6(302-6)2012 Aug

22512287. Homko CJ, Deeb LC, Rohrbacher K, Mulla W, Mastrogiannis D, Gaughan J, Santamore WP, Bove AA, Impact of a telemedicine system with automated reminders on outcomes in women with gestational diabetes mellitus. Diabetes Technol Ther 14:7(624-9)2012 Jul

22450952. Singla S, Keller D, Thirunavukarasu P, Tamandl D, Gupta S, Gaughan J, Dempsey D, Splenic injury during colonoscopy--a complication that warrants urgent attention. J Gastrointest Surg 16:6(1225-34)2012 Jun

22399851. Garfield JL, Marchetti N, Gaughan JP, Steiner RM, Criner GJ, Total lung capacity by plethysmography and high-resolution computed tomography in COPD. Int J Chron Obstruct Pulmon Dis 7:(119-26)2012

22300927. Barakat N, Mohamed FB, Hunter LN, Shah P, Faro SH, Samdani AF, Finsterbusch J, Betz R, Gaughan J, Mulcahey MJ, Diffusion tensor imaging of the normal pediatric spinal cord using an inner field of view echo-planar imaging sequence. AJNR Am J Neuroradiol 33:6(1127-33)2012 Jun

22230131. Spivack DE, Kelly P, Gaughan JP, van Bemmelen PS, Mapping of superficial extremity veins: normal diameters and trends in a vascular patient-population. Ultrasound Med Biol 38:2(190-4)2012 Feb

22186744. Bohm M, Malik Z, Sebastiano C, Thomas R, Gaughan J, Kelsen S, Richter JE, Mucosal eosinophilia: prevalence and racial/ethnic differences in symptoms and endoscopic findings in adults over 10 years in an urban hospital. J Clin Gastroenterol 46:7(567-74)2012 Aug

22016001. Piposar J, Fowler JR, Gaughan JP, Rehman S, Race may not affect [correct] outcomes in operatively treated tibia fractures. Clin Orthop Relat Res 470:5(1513-7)2012 May

21928415. Andrews G, Lango M, Cohen R, Feigenberg S, Burtness B, Mehra R, Ahmed S, Nicolaou N, Gaughan J, Ridge JA, Nonsurgical management of oropharyngeal, laryngeal, and hypopharyngeal cancer: the Fox Chase Cancer Center experience. Head Neck 33:10(1433-40)2011 Oct

21826405. Breslow JM, Monroy MA, Daly JM, Meissler JJ, Gaughan J, Adler MW, Eisenstein TK, Morphine, but not trauma, sensitizes to systemic Acinetobacter baumannii infection. J Neuroimmune Pharmacol 6:4(551-65)2011 Dec

21811179. Hernandez E, De La Mota J, Thomas MB, Huang Y, Gaughan JP, Wang F, Surgical-pathologic risk factors and immunohistochemical markers of pelvic lymph node metastasis in stage IB1 cervical cancer. J Low Genit Tract Dis 15:4(303-8)2011 Oct

21780848. Fowler JR, Gaughan JP, Boden BP, Pavlov H, Torg JS, The non-surgical and surgical treatment of tarsal navicular stress fractures. Sports Med 41:8(613-9)2011 Aug 1

21629130. Maurer AH, Burshteyn M, Adler LP, Gaughan JP, Steiner RM, Variable cardiac 18FDG patterns seen in oncologic positron emission tomography computed tomography: importance for differentiating normal physiology from cardiac and paracardiac disease. J Thorac Imaging 27:4(263-8)2012 Jul

21576323. Breslow JM, Meissler JJ Jr, Hartzell RR, Spence PB, Truant A, Gaughan J, Eisenstein TK, Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance. Infect Immun 79:8(3317-27)2011 Aug

21573034. Mamary AJ, Kondapaneni S, Vance GB, Gaughan JP, Martin UJ, Criner GJ, Survival in Patients Receiving Prolonged Ventilation: Factors that Influence Outcome. Clin Med Insights Circ Respir Pulm Med 5:(17-26)2011 Apr 25

21513441. Krachman SL, Chatila W, Martin UJ, Permut I, D'Alonzo GE, Gaughan JP, Sternberg AL, Ciccolella D, Criner GJ, Physiologic correlates of sleep quality in severe emphysema. COPD 8:3(182-8)2011 Jun

21495839. Kim V, Garfield JL, Grabianowski CL, Krahnke JS, Gaughan JP, Jacobs MR, Criner GJ, The effect of chronic sputum production on respiratory symptoms in severe COPD. COPD 8:2(114-20)2011 Apr

21495833. Marchetti N, Ciccolella DE, Jacobs MR, Crookshank A, Gaughan JP, Kashem MA, Bove AA, Criner GJ, Hospitalized acute exacerbation of COPD impairs flow and nitroglycerin-mediated peripheral vascular dilation. COPD 8:2(60-5)2011 Apr

21487073. Lee YS, VandeVoort CA, Gaughan JP, Midic U, Obradovic Z, Latham KE, Extensive effects of in vitro oocyte maturation on rhesus monkey cumulus cell transcriptome. Am J Physiol Endocrinol Metab 301:1(E196-209)2011 Jul

21332597. Verrengia M, Sachdeva P, Gaughan J, Fisher RS, Parkman HP, Variation of symptoms during the menstrual cycle in female patients with gastroparesis. Neurogastroenterol Motil 23:7(625-e254)2011 Jul

21233227. Mohamed FB, Hunter LN, Barakat N, Liu CS, Sair H, Samdani AF, Betz RR, Faro SH, Gaughan J, Mulcahey MJ, Diffusion tensor imaging of the pediatric spinal cord at 1.5T: preliminary results. AJNR Am J Neuroradiol 32:2(339-45)2011 Feb

21145475. Isiadinso I, Meshkov AB, Gaughan J, Sandhu P, Lim S, Cordova F, Criner G, Atrial arrhythmias after lung and heart-lung transplant: effects on short-term mortality and the influence of amiodarone. J Heart Lung Transplant 30:1(37-44)2011 Jan

21142467. Levene HB, Elliott MB, Gaughan JP, Loftus CM, Tuma RF, Jallo JI, A murine model of hypertonic saline as a treatment for acute spinal cord injury: effects on autonomic outcome. J Neurosurg Spine 14:1(131-8)2011 Jan

21079443. Tierney RT, Mansell JL, Higgins M, McDevitt JK, Toone N, Gaughan JP, Mishra A, Krynetskiy E, Apolipoprotein E genotype and concussion in college athletes. Clin J Sport Med 20:6(464-8)2010 Nov

21063774. Parkman HP, Jacobs MR, Mishra A, Hurdle JA, Sachdeva P, Gaughan JP, Krynetskiy E, Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects. Dig Dis Sci 56:1(115-24)2011 Jan

20963527. Fowler JR, Gaughan JP, Ilyas AM, The sensitivity and specificity of ultrasound for the diagnosis of carpal tunnel syndrome: a meta-analysis. Clin Orthop Relat Res 469:4(1089-94)2011 Apr

20838128. Seamon MJ, Franco MJ, Stawicki SP, Smith BP, Kulp H, Goldberg AJ, Santora TA, Gaughan JP, Do chronic liver disease scoring systems predict outcomes in trauma patients with liver disease? A comparison of MELD and CTP. J Trauma 69:3(568-73)2010 Sep

20733513. Jaffe JK, Paladugu S, Gaughan JP, Parkman HP, Characteristics of nausea and its effects on quality of life in diabetic and idiopathic gastroparesis. J Clin Gastroenterol 45:4(317-21)2011 Apr

20688146. Breslow JM, Feng P, Meissler JJ, Pintar JE, Gaughan J, Adler MW, Eisenstein TK, Potentiating effect of morphine on oral Salmonella enterica serovar Typhimurium infection is µ-opioid receptor-dependent. Microb Pathog 49:6(330-5)2010 Dec

20661447. Turan N, Katari S, Gerson LF, Chalian R, Foster MW, Gaughan JP, Coutifaris C, Sapienza C, Inter- and intra-individual variation in allele-specific DNA methylation and gene expression in children conceived using assisted reproductive technology. PLoS Genet 6:7(e1001033)2010 Jul 22

20642319. Geifman-Holtzman O, Xiong Y, Holtzman EJ, Hoffman B, Gaughan J, Liebermann DA, Increased placental telomerase mRNA in hypertensive disorders of pregnancy. Hypertens Pregnancy 29:4(434-45)2010

20572416. Permut I, Diaz-Abad M, Chatila W, Crocetti J, Gaughan JP, D'Alonzo GE, Krachman SL, Comparison of positional therapy to CPAP in patients with positional obstructive sleep apnea. J Clin Sleep Med 6:3(238-43)2010 Jun 15

20539171. Seamon MJ, Feather C, Smith BP, Kulp H, Gaughan JP, Goldberg AJ, Just one drop: the significance of a single hypotensive blood pressure reading during trauma resuscitations. J Trauma 68:6(1289-94; discussion 1294-1295)2010 Jun

20397809. Kim V, Pechulis RM, Abuel-Haija M, Solomides CC, Gaughan JP, Criner GJ, Small airway pathology and bronchoreversibility in advanced emphysema. COPD 7:2(93-101)2010 Apr

20197494. Torg JS, Moyer J, Gaughan JP, Boden BP, Management of tarsal navicular stress fractures: conservative versus surgical treatment: a meta-analysis. Am J Sports Med 38:5(1048-53)2010 May

20189598. Karachristos A, Herrera A, Sifontis NM, Darrah J, Baribault C, Lee I, Leech SH, Constantinescu S, Gaughan J, Jain A, Silva P, Daller JA, Outcomes of renal transplantation in older high risk recipients: is there an age effect? J Surg Res 161:2(173-8)2010 Jun 15

20163775. Molina EJ, Gupta D, Palma J, Gaughan JP, Macha M, Right ventricular beneficial effects of intracoronary SERCA2a gene transfer in an experimental model of heart failure. Folia Biol (Praha) 56:1(1-8)2010

20013099. Molina EJ, Short S, Monteiro G, Gaughan JP, Macha M, Symptomatic gastroesophageal reflux disease after lung transplantation. Gen Thorac Cardiovasc Surg 57:12(647-53)2009 Dec

20009674. Seamon MJ, Shiroff AM, Franco M, Stawicki SP, Molina EJ, Gaughan JP, Reilly PM, Schwab CW, Pryor JP, Goldberg AJ, Emergency department thoracotomy for penetrating injuries of the heart and great vessels: an appraisal of 283 consecutive cases from two urban trauma centers. J Trauma 67:6(1250-7; discussion 1257-8)2009 Dec

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