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Frank Friedenberg, MD, MSEpi


Frank Friedenberg, MD, MSEpi


Professor, Medicine

Telephone:  215-707-9900

FAX: 215-707-2684

Email: friedfk@tuhs.temple.edu


Department of Medicine, Section of Gastroenterology


Educational Background:


BS, Albright College


MD, Temple University School of Medicine


Internship and Residency, Temple University Hospital


Chief Resident, Temple University Hospital


GI Fellowship, Yale-New Haven Hospital and Albert Einstein Medical Center


Master of (Epidemiology) Science, Temple University, Philadelphia, PA


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  • Internal Medicine
  • Gastroenterology

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clinical Interests:


  • Gastroparesis
  • Functional dyspepsia
  • Inflammatory bowel disease

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research interests:


  • Prevalence and risk factors for reflux and functional bowel disorders in minorities

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extramural funding:


  • National Institutes of Health Mid-career Investigator Award (K24)
  • Industry

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

26422462. Weiss A, Friedenberg F, Patterns of cannabis use in patients with Inflammatory Bowel Disease: A population based analysis. Drug Alcohol Depend 156:(84-9)2015 Nov 1

25883704. Malamood M, Nellis E, Ehrlich AC, Friedenberg FK, Vancomycin Enemas as Adjunctive Therapy for Clostridium difficile Infection. J Clin Med Res 7:6(422-7)2015 Jun

25600163. Homko CJ, Duffy F, Friedenberg FK, Boden G, Parkman HP, Effect of dietary fat and food consistency on gastroparesis symptoms in patients with gastroparesis. Neurogastroenterol Motil 27:4(501-8)2015 Apr

25273122. Iorio N, Makipour K, Palit A, Friedenberg FK, Post-traumatic Stress Disorder Is Associated With Irritable Bowel Syndrome in African Americans. J Neurogastroenterol Motil 20:4(523-30)2014 Oct 30

25090450. Gotfried J, Bernstein M, Ehrlich AC, Friedenberg FK, Administrative Database Research Overestimates the Rate of Interval Colon Cancer. J Clin Gastroenterol 49:6(483-90)2015 Jul

24749828. Iorio N, Sawaya RA, Friedenberg FK, Review article: the biology, diagnosis and management of gastrointestinal stromal tumours. Aliment Pharmacol Ther 39:12(1376-86)2014 Jun

24641690. Natalini J, Palit A, Sankineni A, Friedenberg FK, Diabetes mellitus is an independent risk for gastroesophageal reflux disease among urban African Americans. Dis Esophagus 28:5(405-11)2015 Jul

24612157. Makipour K, Modiri AN, Ehrlich A, Friedenberg FK, Maranki J, Enestvedt BK, Heller S, Tokar J, Haluszka O, Double balloon enteroscopy: effective and minimally invasive method for removal of retained video capsules. Dig Endosc 26:5(646-9)2014 Sep

24503366. Chang P, Friedenberg F, Obesity and GERD. Gastroenterol Clin North Am 43:1(161-73)2014 Mar

24033532. Makhani M, Midani D, Goldberg A, Friedenberg FK, Pathogenesis and outcomes of traumatic injuries of the esophagus. Dis Esophagus 27:7(630-6)2014 Sep-Oct

24007408. Rothstein RD, Friedenberg FK, Linaclotide: a novel compound for the treatment of irritable bowel syndrome with constipation. Expert Opin Pharmacother 14:15(2125-32)2013 Oct

23482920. Modiri A, Makipour K, Gomez J, Friedenberg F, Predictors of colorectal cancer testing using the California Health Inventory Survey. World J Gastroenterol 19:8(1247-55)2013 Feb 28

23426455. Friedenberg FK, Kowalczyk M, Parkman HP, The influence of race on symptom severity and quality of life in gastroparesis. J Clin Gastroenterol 47:9(757-61)2013 Oct

23237330. Friedenberg FK, Makipour K, Palit A, Shah S, Vanar V, Richter JE, Population-based assessment of heartburn in urban Black Americans. Dis Esophagus 26:6(561-9)2013 Aug

22746302. Sawaya RA, Jaffe J, Friedenberg L, Friedenberg FK, Vitamin, mineral, and drug absorption following bariatric surgery. Curr Drug Metab 13:9(1345-55)2012 Nov

22720305. Tang DM, Simmons K, Friedenberg FK, Anti-hypertensive therapy and risk factors associated with hypotension during colonoscopy under conscious sedation. J Gastrointestin Liver Dis 21:2(165-70)2012 Jun

22711499. McKenna T, Macgill A, Porat G, Friedenberg FK, Colonoscopy preparation: polyethylene glycol with Gatorade is as safe and efficacious as four liters of polyethylene glycol with balanced electrolytes. Dig Dis Sci 57:12(3098-105)2012 Dec

22590983. Tang DM, Pathikonda M, Harrison M, Fisher RS, Friedenberg FK, Parkman HP, Symptoms and esophageal motility based on phenotypic findings of scleroderma. Dis Esophagus 26:2(197-203)2013 Feb-Mar

22179971. Friedenberg FK, Dadabhai A, Palit A, Sankineni A, The impact of functional constipation on quality of life of middle-aged Black Americans: a prospective case-control study. Qual Life Res 21:10(1713-7)2012 Dec

22150623. Galli JA, Sawaya RA, Friedenberg FK, Cannabinoid hyperemesis syndrome. Curr Drug Abuse Rev 4:4(241-9)2011 Dec

22052446. Friedenberg FK, Singh M, George NS, Sankineni A, Shah S, Prevalence and distribution of adenomas in black Americans undergoing colorectal cancer screening. Dig Dis Sci 57:2(489-95)2012 Feb

21966890. Sawaya RA, Macgill A, Parkman HP, Friedenberg FK, Use of the Montreal global definition as an assessment of quality of life in reflux disease. Dis Esophagus 25:6(477-83)2012 Aug

21869874. Friedenberg FK, GERD in Minority Populations. Gastroenterol Hepatol (N Y) 7:6(411-3)2011 Jun

21629040. Friedenberg FK, Tang DM, Vanar V, Mendonca T, Predictive value of body mass index at age 18 on adulthood obesity: results of a prospective survey of an urban population. Am J Med Sci 342:5(371-82)2011 Nov

21311721. Friedenberg FK, Rai J, Vanar V, Bongiorno C, Nelson DB, Parepally M, Poonia A, Sharma A, Gohel S, Richter JE, Prevalence and risk factors for gastroesophageal reflux disease in an impoverished minority population. Obes Res Clin Pract 4:4(e261-e269)2010 Oct

21162694. Adamcewicz M, Bearelly D, Porat G, Friedenberg FK, Mechanism of action and toxicities of purgatives used for colonoscopy preparation. Expert Opin Drug Metab Toxicol 7:1(89-101)2011 Jan

24345691. Friedenberg FK, Rai J, Vanar V, Bongiorno C, Nelson DB, Parepally M, Poonia A, Sharma A, Gohel S, Richter JE, Prevalence and risk factors for gastroesophageal reflux disease in an impoverished minority population. Obes Res Clin Pract 4:4(e247-342)2010 Oct-Dec

20215751. Doma S, Paladugu S, Parkman HP, Friedenberg FK, Wireless capsules for esophageal pH monitoring: are we placing them correctly? Digestion 82:1(54-9)2010

19830561. Friedenberg FK, Hanlon A, Vanar V, Nehemia D, Mekapati J, Nelson DB, Richter JE, Trends in gastroesophageal reflux disease as measured by the National Ambulatory Medical Care Survey. Dig Dis Sci 55:7(1911-7)2010 Jul

19655250. Maqbool S, Parkman HP, Friedenberg FK, Wireless capsule motility: comparison of the SmartPill GI monitoring system with scintigraphy for measuring whole gut transit. Dig Dis Sci 54:10(2167-74)2009 Oct

19236223. Dadabhai A, Friedenberg FK, Rabeprazole: a pharmacologic and clinical review for acid-related disorders. Expert Opin Drug Saf 8:1(119-26)2009 Jan

19033686. Cassilly DW, Wang YR, Friedenberg FK, Nelson DB, Maurer AH, Parkman HP, Symptoms of gastroparesis: use of the gastroparesis cardinal symptom index in symptomatic patients referred for gastric emptying scintigraphy. Digestion 78:2-3(144-51)2008

18829390. Friedenberg FK, Parkman HP, Persistent nausea and abdominal pain in a patient with delayed gastric emptying. Clin Gastroenterol Hepatol 6:12(1309-14)2008 Dec

18796104. Friedenberg FK, Xanthopoulos M, Foster GD, Richter JE, The association between gastroesophageal reflux disease and obesity. Am J Gastroenterol 103:8(2111-22)2008 Aug

18684189. Wang YR, Dempsey DT, Friedenberg FK, Richter JE, Trends of Heller myotomy hospitalizations for achalasia in the United States, 1993-2005: effect of surgery volume on perioperative outcomes. Am J Gastroenterol 103:10(2454-64)2008 Oct

18270828. Andanappa HK, Dai Q, Korimilli A, Panganamamula K, Friedenberg F, Miller L, Acoustic liver biopsy using endoscopic ultrasound. Dig Dis Sci 53:4(1078-83)2008 Apr

18270827. Friedenberg FK, Desipio J, Korimilli A, Bohning M, Sum E, Parkman HP, Richter JE, Fisher RS, Tonic and phasic pyloric activity in response to CCK-octapeptide. Dig Dis Sci 53:4(905-11)2008 Apr

18179614. Sise A, Friedenberg FK, A comprehensive review of gastroesophageal reflux disease and obesity. Obes Rev 9:3(194-203)2008 May

18080765. Maranki JL, Lytes V, Meilahn JE, Harbison S, Friedenberg FK, Fisher RS, Parkman HP, Predictive factors for clinical improvement with Enterra gastric electric stimulation treatment for refractory gastroparesis. Dig Dis Sci 53:8(2072-8)2008 Aug

18070232. Friedenberg FK, Palit A, Parkman HP, Hanlon A, Nelson DB, Botulinum toxin A for the treatment of delayed gastric emptying. Am J Gastroenterol 103:2(416-23)2008 Feb

17761121. Friedenberg FK, Parkman HP, Advances in the management of gastroparesis. Curr Treat Options Gastroenterol 10:4(283-93)2007 Aug

17546484. Nelson DB, Bellamy S, Clothier BA, Macones GA, Nachamkin I, Ruffin A, Allen-Taylor L, Friedenberg FK, Characteristics and pregnancy outcomes of pregnant women asymptomatic for bacterial vaginosis. Matern Child Health J 12:2(216-22)2008 Mar

17300288. Desipio J, Friedenberg FK, Korimilli A, Richter JE, Parkman HP, Fisher RS, High-resolution solid-state manometry of the antropyloroduodenal region. Neurogastroenterol Motil 19:3(188-95)2007 Mar

16836948. Friedenberg FK, Parkman HP, Delayed gastric emptying: whom to test, how to test, and what to do. Curr Treat Options Gastroenterol 9:4(295-304)2006 Jul

16340634. Modena S, Gollamudi S, Friedenberg F, Continuation of antibiotics is associated with failure of metronidazole for Clostridium difficile-associated diarrhea. J Clin Gastroenterol 40:1(49-54)2006 Jan

16206495. Friedenberg FK, Parkman HP, Management of delayed gastric emptying. Clin Gastroenterol Hepatol 3:7(642-6)2005 Jul

16197490. Chang A, Skole K, Gautam M, Schmutz J, Black M, Thomas R, Horwitz B, Friedenberg FK, The impact of past alcohol use on treatment response rates in patients with chronic hepatitis C. Aliment Pharmacol Ther 22:8(701-6)2005 Oct 15

16156324. Modena S, Bearelly D, Swartz K, Friedenberg FK, Clostridium difficile among hospitalized patients receiving antibiotics: a case-control study. Infect Control Hosp Epidemiol 26:8(685-90)2005 Aug

15933684. Bromer MQ, Friedenberg F, Miller LS, Fisher RS, Swartz K, Parkman HP, Endoscopic pyloric injection of botulinum toxin A for the treatment of refractory gastroparesis. Gastrointest Endosc 61:7(833-9)2005 Jun

15104353. Friedenberg F, Gollamudi S, Parkman HP, The use of botulinum toxin for the treatment of gastrointestinal motility disorders. Dig Dis Sci 49:2(165-75)2004 Feb

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