about | Maps & Directions | contact | admissions | faculty | alumni & development | library | Tech Support Center | dean's office | Policies & Procedures

FAculty directory

Back to alphabetical index

Paul Forfia, MD


Paul Forfia, MD


Director, Pulmonary Hypertension/Right Heart Failure and Pulmonary Thromboendarterectomy Program

Associate Professor of Medicine

Telephone: 215-707-5800

Email: paul.forfia@tuhs.temple.edu


Department of Medicine, Section of Cardiology


Educational Background:


BS, Biology, The Ohio State University, Columbus, OH


MS, Physiology, New York Medical College, New York, NY


MD, New York Medical College, New York, NY


Internship, Medicine, Johns Hopkins Hospital, Baltimore, MD


Residency, Medicine, Johns Hopkins Hospital, Baltimore, MD


Fellowship, Cardiology, Johns Hopkins Hospital, Baltimore, MD


Fellowship, Heart Failure/Transplantation, Johns Hopkins Hospital, Baltimore, MD

Return to top



clinical and Research interests:


  • Pulmonary hypertension and right-sided heart failure
  • Acute and chronic thromboembolic disease
  • Right ventricular disease
  • Valvular heart disease
  • Cardiopulmonary diseases
  • Cardiomyopathies
  • Heart transplant
  • Congenital heart disease associated pulmonary hypertension

Return to top



board certification(s):


  • Advanced heart failure and transplantation
  • Cardiovascular disease
  • Internal medicine

Return to top



professional affiliations:


  • American College of Cardiology
  • American College of Chest Physicians
  • Pulmonary Vascular Research Institute

Return to top



Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

25912147. Davila CD, Forfia PR, Management of severe pulmonary hypertension in patients undergoing mitral valve surgery. Curr Treat Options Cardiovasc Med 17:6(382)2015 Jun

25697032. Vonk-Noordegraaf A, Haddad F, Chin KM, Forfia PR, Kawut SM, Lumens J, Naeije R, Newman J, Oudiz RJ, Provencher S, Torbicki A, Voelkel NF, Hassoun PM, [Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology]. Turk Kardiyol Dern Ars 42 Suppl 1:(29-44)2014 Oct

25534670. Naeije R, D'Alto M, Forfia PR, Clinical and research measurement techniques of the pulmonary circulation: the present and the future. Prog Cardiovasc Dis 57:5(463-72)2015 Mar-Apr

24789425. Saggar R, Khanna D, Forfia PR, Saggar R, Il buono, il brutto, il cattivo. Thorax 69:9(871-2)2014 Sep

24431095. Saggar R, Khanna D, Vaidya A, Derhovanessian A, Maranian P, Duffy E, Belperio JA, Weigt SS, Dua S, Shapiro SS, Goldin JG, Abtin F, Lynch JP 3rd, Ross DJ, Forfia PR, Saggar R, Changes in right heart haemodynamics and echocardiographic function in an advanced phenotype of pulmonary hypertension and right heart dysfunction associated with pulmonary fibrosis. Thorax 69:2(123-9)2014 Feb

24355638. Vonk-Noordegraaf A, Haddad F, Chin KM, Forfia PR, Kawut SM, Lumens J, Naeije R, Newman J, Oudiz RJ, Provencher S, Torbicki A, Voelkel NF, Hassoun PM, Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology. J Am Coll Cardiol 62:25 Suppl(D22-33)2013 Dec 24

24304365. Okada DR, Rahmouni HW, Herrmann HC, Bavaria JE, Forfia PR, Han Y, Assessment of right ventricular function by transthoracic echocardiography following aortic valve replacement. Echocardiography 31:5(552-7)2014 May

24280251. Opotowsky AR, Santos M, Maron BA, Afilalo J, Waxman AB, Landzberg MJ, Forfia PR, Towards widespread noninvasive assessment of pulmonary vascular resistance in clinical practice. J Am Soc Echocardiogr 27:1(108-9)2014 Jan

24267297. Forfia PR, Trow TK, Diagnosis of pulmonary arterial hypertension. Clin Chest Med 34:4(665-81)2013 Dec

23928091. Mercer-Rosa L, Parnell A, Forfia PR, Yang W, Goldmuntz E, Kawut SM, Tricuspid annular plane systolic excursion in the assessment of right ventricular function in children and adolescents after repair of tetralogy of Fallot. J Am Soc Echocardiogr 26:11(1322-9)2013 Nov

23884296. Mazurek JA, Forfia PR, Enhancing the accuracy of echocardiography in the diagnosis of pulmonary arterial hypertension: looking at the heart to learn about the lungs. Curr Opin Pulm Med 19:5(437-45)2013 Sep

23773508. Raina A, Vaidya A, Gertz ZM, Susan Chambers, Forfia PR, Marked changes in right ventricular contractile pattern after cardiothoracic surgery: implications for post-surgical assessment of right ventricular function. J Heart Lung Transplant 32:8(777-83)2013 Aug

23735649. Opotowsky AR, Clair M, Afilalo J, Landzberg MJ, Waxman AB, Moko L, Maron BA, Vaidya A, Forfia PR, A simple echocardiographic method to estimate pulmonary vascular resistance. Am J Cardiol 112:6(873-82)2013 Sep 15

23704061. Gertz ZM, McCauley BD, Raina A, O'Donnell W, Shellenberger C, Willhide J, Forfia PR, Herrmann HC, Estimation of oxygen consumption in elderly patients with aortic stenosis. Catheter Cardiovasc Interv 83:1(E128-33)2014 Jan 1

23663810. Testani JM, Brisco MA, Tang WH, Kimmel SE, Tiku-Owens A, Forfia PR, Coca SG, Potential effects of digoxin on long-term renal and clinical outcomes in chronic heart failure. J Card Fail 19:5(295-302)2013 May

23662171. Forfia PR, Vaidya A, Wiegers SE, Pulmonary heart disease: The heart-lung interaction and its impact on patient phenotypes. Pulm Circ 3:1(5-19)2013 Jan

23547564. Elinoff JM, Rame JE, Forfia PR, Hall MK, Sun J, Gharib AM, Abd-Elmoniem K, Graninger G, Harper B, Danner RL, Solomon MA, A pilot study of the effect of spironolactone therapy on exercise capacity and endothelial dysfunction in pulmonary arterial hypertension: study protocol for a randomized controlled trial. Trials 14:(91)2013 Apr 2

23450321. Rivera-Lebron BN, Forfia PR, Kreider M, Lee JC, Holmes JH, Kawut SM, Echocardiographic and hemodynamic predictors of mortality in idiopathic pulmonary fibrosis. Chest 144:2(564-70)2013 Aug

22921027. Forfia PR, Vachiéry JL, Echocardiography in pulmonary arterial hypertension. Am J Cardiol 110:6 Suppl(16S-24S)2012 Sep 15

22914595. Opotowsky AR, Ojeda J, Rogers F, Prasanna V, Clair M, Moko L, Vaidya A, Afilalo J, Forfia PR, A simple echocardiographic prediction rule for hemodynamics in pulmonary hypertension. Circ Cardiovasc Imaging 5:6(765-75)2012 Nov

22647520. Gertz ZM, Raina A, O'Donnell W, McCauley BD, Shellenberger C, Kolansky DM, Wilensky RL, Forfia PR, Herrmann HC, Comparison of invasive and noninvasive assessment of aortic stenosis severity in the elderly. Circ Cardiovasc Interv 5:3(406-14)2012 Jun

22371450. Forfia PR, Borlaug BA, Letter by Forfia and Borlaug regarding article, "Pulmonary hypertension in heart failure with preserved ejection fraction: a target of phosphodiesterase-5 inhibition in a 1-year study". Circulation 125:8(e408; author reply e409-10)2012 Feb 28

22034604. Roberts JD, Forfia PR, Diagnosis and assessment of pulmonary vascular disease by Doppler echocardiography. Pulm Circ 1:2(160-81)2011 Apr-Jun

21965638. Mathai SC, Sibley CT, Forfia PR, Mudd JO, Fisher MR, Tedford RJ, Lechtzin N, Boyce D, Hummers LK, Housten T, Zaiman AL, Girgis RE, Hassoun PM, Tricuspid annular plane systolic excursion is a robust outcome measure in systemic sclerosis-associated pulmonary arterial hypertension. J Rheumatol 38:11(2410-8)2011 Nov

21106653. Brown SB, Raina A, Katz D, Szerlip M, Wiegers SE, Forfia PR, Longitudinal shortening accounts for the majority of right ventricular contraction and improves after pulmonary vasodilator therapy in normal subjects and patients with pulmonary arterial hypertension. Chest 140:1(27-33)2011 Jul

20888527. Opotowsky AR, Ojeda J, Rogers F, Arkles J, Liu T, Forfia PR, Blood pressure response to the valsalva maneuver. A simple bedside test to determine the hemodynamic basis of pulmonary hypertension. J Am Coll Cardiol 56:16(1352-3)2010 Oct 12

20709819. Arkles JS, Opotowsky AR, Ojeda J, Rogers F, Liu T, Prassana V, Marzec L, Palevsky HI, Ferrari VA, Forfia PR, Shape of the right ventricular Doppler envelope predicts hemodynamics and right heart function in pulmonary hypertension. Am J Respir Crit Care Med 183:2(268-76)2011 Jan 15

20688926. Methvin AB, Owens AT, Emmi AG, Allen M, Wiegers SE, Dries DL, Margulies KB, Forfia PR, Ventilatory inefficiency reflects right ventricular dysfunction in systolic heart failure. Chest 139:3(617-25)2011 Mar

19643943. Mathai SC, Bueso M, Hummers LK, Boyce D, Lechtzin N, Le Pavec J, Campo A, Champion HC, Housten T, Forfia PR, Zaiman AL, Wigley FM, Girgis RE, Hassoun PM, Disproportionate elevation of N-terminal pro-brain natriuretic peptide in scleroderma-related pulmonary hypertension. Eur Respir J 35:1(95-104)2010 Jan

19624796. Hemnes AR, Forfia PR, Champion HC, Assessment of pulmonary vasculature and right heart by invasive haemodynamics and echocardiography. Int J Clin Pract Suppl :162(4-19)2009 Sep

19164700. Fisher MR, Forfia PR, Chamera E, Housten-Harris T, Champion HC, Girgis RE, Corretti MC, Hassoun PM, Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med 179:7(615-21)2009 Apr 1

18356560. Forfia PR, Mathai SC, Fisher MR, Housten-Harris T, Hemnes AR, Champion HC, Girgis RE, Hassoun PM, Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension. Am J Respir Crit Care Med 177:12(1364-9)2008 Jun 15

17761115. Forfia PR, Approach to patients with heart failure and pulmonary hypertension. Curr Treat Options Cardiovasc Med 9:4(302-9)2007 Aug

17349888. Forfia PR, Lee M, Tunin RS, Mahmud M, Champion HC, Kass DA, Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not normal canine heart. J Am Coll Cardiol 49:10(1079-88)2007 Mar 13

16888289. Forfia PR, Fisher MR, Mathai SC, Housten-Harris T, Hemnes AR, Borlaug BA, Chamera E, Corretti MC, Champion HC, Abraham TP, Girgis RE, Hassoun PM, Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med 174:9(1034-41)2006 Nov 1

15893185. Forfia PR, Watkins SP, Rame JE, Stewart KJ, Shapiro EP, Relationship between B-type natriuretic peptides and pulmonary capillary wedge pressure in the intensive care unit. J Am Coll Cardiol 45:10(1667-71)2005 May 17

15591228. Katori T, Hoover DB, Ardell JL, Helm RH, Belardi DF, Tocchetti CG, Forfia PR, Kass DA, Paolocci N, Calcitonin gene-related peptide in vivo positive inotropy is attributable to regional sympatho-stimulation and is blunted in congestive heart failure. Circ Res 96:2(234-43)2005 Feb 4

10942168. Mital S, Magneson A, Loke KE, Liao J, Forfia PR, Hintze TH, Simvastatin acts synergistically with ACE inhibitors or amlodipine to decrease oxygen consumption in rat hearts. J Cardiovasc Pharmacol 36:2(248-54)2000 Aug

10659170. Forfia PR, Hintze TH, Wolin MS, Kaley G, Role of nitric oxide in the control of mitochondrial function. Adv Exp Med Biol 471:(381-8)1999

10630737. Loke KE, Forfia PR, Recchia FA, Xu X, Osorio JC, Ochoa M, Gawryl M, Hintze TH, Bovine polymerized hemoglobin increases cardiac oxygen consumption and alters myocardial substrate metabolism in conscious dogs: role of nitric oxide. J Cardiovasc Pharmacol 35:1(84-92)2000 Jan

10362689. Forfia PR, Zhang X, Knight DR, Smith AH, Doe CP, Wolfgang EA, Flynn DM, Wolin MS, Hintze TH, NO modulates myocardial O2 consumption in the nonhuman primate: an additional mechanism of action of amlodipine. Am J Physiol 276:6 Pt 2(H2069-75)1999 Jun

9648722. Laycock SK, Vogel T, Forfia PR, Tuzman J, Xu X, Ochoa M, Thompson CI, Nasjletti A, Hintze TH, Role of nitric oxide in the control of renal oxygen consumption and the regulation of chemical work in the kidney. Circ Res 82:12(1263-71)1998 Jun 29

9458868. Forfia PR, Zhang X, Ochoa F, Ochoa M, Xu X, Bernstein R, Sehgal PB, Ferreri NR, Hintze TH, Relationship between plasma NOx and cardiac and vascular dysfunction after LPS injection in anesthetized dogs. Am J Physiol 274:1 Pt 2(H193-201)1998 Jan

7796509. Zeballos GA, Bernstein RD, Thompson CI, Forfia PR, Seyedi N, Shen W, Kaminiski PM, Wolin MS, Hintze TH, Pharmacodynamics of plasma nitrate/nitrite as an indication of nitric oxide formation in conscious dogs. Circulation 91:12(2982-8)1995 Jun 15

Return to top