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Nestor F. Esnaola, MD, MPH, MBAnestor f esnaola, md, mph, mba


Vice Chair, Clinical and Academic Affairs, Surgery

Chief, Surgical Oncology

Professor, Surgery

Telephone:  215-707-2072

Email: nestor.esnaola@tuhs.temple.edu


Department of Surgery, Division of

Surgical Oncology


Educational Background:


BA, Rice University, Houston, TX, 1989


MD, Johns Hopkins University School of Medicine, Baltimore, MD, 1993


Internship, Brigham and Women's Hospitall, Harvard Medical School, Boston, MA, 1993-1994


MPH, Harvard School of Public Health, Boston, MA, 1997-1998


Residency, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 1994-2000


Fellowship, University of Texas M. D. Anderson Cancer Center, Houston, TX, 2000-2003


MBA, University of Tennessee, Knoxville, TN, 2007-2008


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clinical Interests:

  • Gastric cancer
  • Pancreatic cancer
  • Hepatobiliary cancer, hepatobiliary surgery
  • Colorectal cancer
  • Peritoneal malignancies
  • Melanoma
  • Sarcoma
  • Liver cancer, liver metastases

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board certification(s):


  • American Board of Surgery

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  • Society of Surgical Oncology
  • American Society of Clinical Oncology
  • Association of Academic Surgeons
  • American College of Surgeons

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Research Interests:


  • Racial/ethnic disparities in cancer care and outcomes
  • Perioperative care, morbility, mortality
  • Novel therapies for hepatopancreatobiliary malignancies
  • Optimal therapy of gastric and rectal cancer

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

25064316. Karachristos A, Esnaola NF, Surgical management of pancreatic neoplasms: what's new? Curr Gastroenterol Rep 16:8(397)2014 Aug

24606850. Esnaola NF, Chaudhary UB, O'Brien P, Garrett-Mayer E, Camp ER, Thomas MB, Cole DJ, Montero AJ, Hoffman BJ, Romagnuolo J, Orwat KP, Marshall DT, Phase 2 trial of induction gemcitabine, oxaliplatin, and cetuximab followed by selective capecitabine-based chemoradiation in patients with borderline resectable or unresectable locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys 88:4(837-44)2014 Mar 15

23806824. Johannesmeyer D, Smith V, Cole DJ, Esnaola NF, Camp ER, The impact of lymph node disease in extremity soft-tissue sarcomas: a population-based analysis. Am J Surg 206:3(289-95)2013 Sep

23280333. Yang Y, Mauldin PD, Ebeling M, Hulsey TC, Liu B, Thomas MB, Camp ER, Esnaola NF, Effect of metabolic syndrome and its components on recurrence and survival in colon cancer patients. Cancer 119:8(1512-20)2013 Apr 15

22917646. Chow WB, Rosenthal RA, Merkow RP, Ko CY, Esnaola NF, Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeons National Surgical Quality Improvement Program and the American Geriatrics Society. J Am Coll Surg 215:4(453-66)2012 Oct

22583991. Esnaola NF, Ford ME, Racial differences and disparities in cancer care and outcomes: where's the rub? Surg Oncol Clin N Am 21:3(417-37, viii)2012 Jul

22326982. Lawson EH, Hall BL, Esnaola NF, Ko CY, Identifying worsening surgical site infection performance: control charts versus risk-adjusted rate outlier status. Am J Med Qual 27:5(391-7)2012 Sep-Oct

21954692. Esnaola NF, Cole DJ, Perioperative normothermia during major surgery: is it important? Adv Surg 45:(249-63)2011

20881777. Lehtinen SJ, Onicescu G, Kuhn KM, Cole DJ, Esnaola NF, Normothermia to prevent surgical site infections after gastrointestinal surgery: holy grail or false idol? Ann Surg 252:4(696-704)2010 Oct

20598257. Wilson JA, Lewin DN, Esnaola NF, Romagnuolo J, Adenocarcinoma arising from a gastric submucosal intraductal papillary mucinous neoplasm. Gastrointest Endosc 71:7(1298-9)2010 Jun

19730243. Esnaola NF, Gebregziabher M, Finney C, Ford ME, Underuse of surgical resection in black patients with nonmetastatic colorectal cancer: location, location, location. Ann Surg 250:4(549-57)2009 Oct

18936578. Esnaola NF, Hall BL, Hosokawa PW, Ayanian JZ, Henderson WG, Khuri SF, Zinner MJ, Rogers SO Jr, Race and surgical outcomes: it is not all black and white. Ann Surg 248:4(647-55)2008 Oct

18712449. Esnaola NF, Stewart AK, Feig BW, Skibber JM, Rodriguez-Bigas MA, Age-, race-, and ethnicity-related differences in the treatment of nonmetastatic rectal cancer: a patterns of care study from the national cancer data base. Ann Surg Oncol 15:11(3036-47)2008 Nov

18573427. Esnaola NF, Gebregziabher M, Knott K, Finney C, Silvestri GA, Reed CE, Ford ME, Underuse of surgical resection for localized, non-small cell lung cancer among whites and African Americans in South Carolina. Ann Thorac Surg 86:1(220-6; discussion 227)2008 Jul

18398659. Esnaola NF, Knott K, Finney C, Gebregziabher M, Ford ME, Urban/rural residence moderates effect of race on receipt of surgery in patients with nonmetastatic breast cancer: a report from the South Carolina central cancer registry. Ann Surg Oncol 15:7(1828-36)2008 Jul

14762844. Pawlik TM, Esnaola NF, Vauthey JN, Surgical treatment of hepatocellular carcinoma: similar long-term results despite geographic variations. Liver Transpl 10:2 Suppl 1(S74-80)2004 Feb

14578734. Esnaola NF, Mirza N, Lauwers GY, Ikai I, Regimbeau JM, Belghiti J, Yamaoka Y, Curley SA, Ellis LM, Nagorney DM, Vauthey JN, Comparison of clinicopathologic characteristics and outcomes after resection in patients with hepatocellular carcinoma treated in the United States, France, and Japan. Ann Surg 238:5(711-9)2003 Nov

12409336. Esnaola NF, Cantor SB, Johnson ML, Mirza AN, Miller AR, Curley SA, Crane CH, Cleeland CS, Janjan NA, Skibber JM, Pain and quality of life after treatment in patients with locally recurrent rectal cancer. J Clin Oncol 20:21(4361-7)2002 Nov 1

11992808. Esnaola NF, Lauwers GY, Mirza NQ, Nagorney DM, Doherty D, Ikai I, Yamaoka Y, Regimbeau JM, Belghiti J, Curley SA, Ellis LM, Vauthey JN, Predictors of microvascular invasion in patients with hepatocellular carcinoma who are candidates for orthotopic liver transplantation. J Gastrointest Surg 6:2(224-32; discussion 232)2002 Mar-Apr

11896101. Vauthey JN, Lauwers GY, Esnaola NF, Do KA, Belghiti J, Mirza N, Curley SA, Ellis LM, Regimbeau JM, Rashid A, Cleary KR, Nagorney DM, Simplified staging for hepatocellular carcinoma. J Clin Oncol 20:6(1527-36)2002 Mar 15

11773178. Esnaola NF, Lazarides SN, Mentzer SJ, Kuntz KM, Outcomes and cost-effectiveness of alternative staging strategies for non-small-cell lung cancer. J Clin Oncol 20:1(263-73)2002 Jan 1

11742318. Esnaola NF, Cantor SB, Sherman SI, Lee JE, Evans DB, Optimal treatment strategy in patients with papillary thyroid cancer: a decision analysis. Surgery 130:6(921-30)2001 Dec

11505068. Esnaola NF, Rubin BP, Baldini EH, Vasudevan N, Demetri GD, Fletcher CD, Singer S, Response to chemotherapy and predictors of survival in adult rhabdomyosarcoma. Ann Surg 234:2(215-23)2001 Aug

10083424. Wu A, Esnaola NF, Yamada K, Awwad M, Shimizu A, Huang C, Wain J, Zhao Y, Neville DM Jr, Cooper DK, Sykes M, Sachs DH, Xenogeneic thymic transplantation in a pig-to-nonhuman primate model. Transplant Proc 31:1-2(957)1999 Feb-Mar

7743325. Schoeniger LO, Curtis W, Esnaola NF, Beck SC, Gardner T, Buchman TG, Myocardial heat shock gene expression in pigs is dependent on superoxide anion generated at reperfusion. Shock 1:1(31-5)1994 Jan

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