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Daniel Edmundowicz, MD, MS, FACC


Daniel Edmundowicz, MD, MS, FACC


Professor, Medicine

Professor of Medicine

Section Chief of Cardiology

Vice Chair of Program Development, Department of Medicine

Telephone:  215-707-5744

Email: daniel.edmundowicz@tuhs.temple.edu



Department of Medicine, Section of Cardiology


Educational Background:


Undergraduate degree, University of Notre Dame, Notre Dame, IN, 1984


MS (Human Anatomy), Drexel University College of Medicine, Philadelphia, PA, 1984-1986


MD, Drexel University College of Medicine, Philadelphia, PA, 1990


Internship and Residency, Temple University Hospital, Philadelphia, PA, 1991-1993


Fellowship (Cardiology), University of Pittsburgh Medical Center, Pittsburgh, PA, 1993-1996


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clinical Interests:

  • Lipidology
  • Preventive cardiology
  • Subclinical vascular disease detection for risk stratification

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board certifications:


  • American Board of Internal Medicine - Internal Medicine, Cardiology

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professional affiliations:

  • Fellow, American College of Cardiology
  • American Heart Association
  • President, Society of Atherosclerosis Imaging and Prevention
  • National Lipid Association

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research interests:


  • Epidemiology of subclinical vascular disease
  • Polyunsaturated fatty acids and their effect on the cardiovascular system

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

26059090. Al Maluli H, Mathur M, Keane MG, Guy TS, Dries D, Edmundowicz D, Multiple Septal Coronary-Cameral Fistulae after Septal Myectomy. Echocardiography 32:11(1736-7)2015 Nov

25885874. Vishnu A, Choo J, Wilcox B, Hisamatsu T, Barinas-Mitchell EJ, Fujiyoshi A, Mackey RH, Kadota A, Ahuja V, Kadowaki T, Edmundowicz D, Miura K, Rodriguez BL, Kuller LH, Shin C, Masaki K, Ueshima H, Sekikawa A, Brachial-ankle pulse wave velocity is associated with coronary calcification among 1131 healthy middle-aged men. Int J Cardiol 189:(67-72)2015 Jun 15

25379191. Lin P, Rhew E, Ness RB, Peaceman A, Dyer A, McPherson D, Kondos GT, Edmundowicz D, Sutton-Tyrrell K, Thompson T, Ramsey-Goldman R, Adverse pregnancy outcomes and subsequent risk of cardiovascular disease in women with systemic lupus erythematosus. Lupus Sci Med 1:1(e000024)2014

25147256. Bacha F, Edmundowicz D, Sutton-Tyrell K, Lee S, Tfayli H, Arslanian SA, Coronary artery calcification in obese youth: what are the phenotypic and metabolic determinants? Diabetes Care 37:9(2632-9)2014 Sep

25109783. El Khoudary SR, Shin C, Masaki K, Miura K, Budoff M, Edmundowicz D, Kadowaki S, Barinas-Mitchell E, El-Saed A, Fujiyoshi A, Evans RW, Hisamatsu T, Ohkubo T, Willcox BJ, Kuller LH, Ueshima H, Sekikawa A, Ectopic cardiovascular fat in middle-aged men: effects of race/ethnicity, overall and central adiposity. The ERA JUMP study. Int J Obes (Lond) 39:3(488-94)2015 Mar

25086078. Mahieu MA, Guild CP, Albert CJ, Kondos GT, Carr JJ, Edmundowicz D, Ford DA, Ramsey-Goldman R, Alpha-chlorofatty Acid and coronary artery or aorta calcium scores in women with systemic lupus erythematosus. A pilot study. J Rheumatol 41:9(1834-42)2014 Sep

25068101. Hirooka N, Shin C, Masaki KH, Edmundowicz D, Choo J, Barinas-Mitchell EJ, Willcox BJ, Sutton-Tyrrell K, El-Saed A, Miljkovic-Gacic I, Ohkubo T, Miura K, Ueshima H, Kuller LH, Sekikawa A, The Associations of Indices of Obesity with Lipoprotein Subfractions in Japanese American, African American and Korean Men. Glob Heart 8:3(273-280)2013 Sep 1

24695552. Yazdanyar A, Aziz MM, Enright PL, Edmundowicz D, Boudreau R, Sutton-Tyrell K, Kuller L, Newman AB, Association Between 6-Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease. J Aging Health 26:4(583-599)2014 Apr 2

24352736. Sekikawa A, Miura K, Lee S, Fujiyoshi A, Edmundowicz D, Kadowaki T, Evans RW, Kadowaki S, Sutton-Tyrrell K, Okamura T, Bertolet M, Masaki KH, Nakamura Y, Barinas-Mitchell EJ, Willcox BJ, Kadota A, Seto TB, Maegawa H, Kuller LH, Ueshima H, Long chain n-3 polyunsaturated fatty acids and incidence rate of coronary artery calcification in Japanese men in Japan and white men in the USA: population based prospective cohort study. Heart 100:7(569-73)2014 Apr

23697588. Azuma K, Curb JD, Kadowaki T, Edmundowicz D, Kadowaki S, Masaki KH, El-Saed A, Nishio Y, Seto TB, Okamura T, Cetinel C, Kadota A, Sutton-Tyrrell K, Miura K, Evans RW, Takamiya T, Maegawa H, Miljkovic I, Kuller LH, Ueshima H, Kelley DE, Sekikawa A, Ethnic difference in liver fat content: a cross-sectional observation among Japanese American in Hawaii, Japanese in Japan, and non-Hispanic whites in United States. Obes Res Clin Pract 7:3(e198-205)2013 May-Jun

23040831. El Khoudary SR, Barinas-Mitchell E, White J, Sutton-Tyrrell K, Kuller LH, Curb JD, Shin C, Ueshima H, Masaki K, Evans RW, Miura K, Edmundowicz D, Sekikawa A, Adiponectin, systolic blood pressure, and alcohol consumption are associated with more aortic stiffness progression among apparently healthy men. Atherosclerosis 225:2(475-80)2012 Dec

22537531. Sekikawa A, Shin C, Curb JD, Barinas-Mitchell E, Masaki K, El-Saed A, Seto TB, Mackey RH, Choo J, Fujiyoshi A, Miura K, Edmundowicz D, Kuller LH, Ueshima H, Sutton-Tyrrell K, Aortic stiffness and calcification in men in a population-based international study. Atherosclerosis 222:2(473-7)2012 Jun

22505860. Luyster FS, Kip KE, Drumheller OJ, Rice TB, Edmundowicz D, Matthews K, Reis SE, Strollo PJ Jr, Sleep apnea is related to the atherogenic phenotype, lipoprotein subclass B. J Clin Sleep Med 8:2(155-61)2012 Apr 15

22485011. Sekikawa A, Curb JD, Edmundowicz D, Okamura T, Choo J, Fujiyoshi A, Masaki K, Miura K, Kuller LH, Shin C, Ueshima H, Coronary artery calcification by computed tomography in epidemiologic research and cardiovascular disease prevention. J Epidemiol 22:3(188-98)2012

22240754. El-Saed A, Curb JD, Kadowaki T, Okamura T, Sutton-Tyrrell K, Masaki K, Seto TB, Takamiya T, Choo J, Edmundowicz D, Evans RW, Fujiyoshi A, Nakamura Y, Miura K, Shin C, Kuller LH, Ueshima H, Sekikawa A, The prevalence of aortic calcification in Japanese compared to white and Japanese-American middle-aged men is confounded by the amount of cigarette smoking. Int J Cardiol 167:1(134-9)2013 Jul 15

22174200. Greco CM, Li T, Sattar A, Kao AH, Danchenko N, Edmundowicz D, Sutton-Tyrrell K, Tracy RP, Kuller LH, Manzi S, Association between depression and vascular disease in systemic lupus erythematosus. J Rheumatol 39:2(262-8)2012 Feb

22042881. Low CA, Matthews KA, Kuller LH, Edmundowicz D, Psychosocial predictors of coronary artery calcification progression in postmenopausal women. Psychosom Med 73:9(789-94)2011 Nov-Dec

21846428. Lee S, Curb JD, Kadowaki T, Evans RW, Miura K, Takamiya T, Shin C, El-Saed A, Choo J, Fujiyoshi A, Otake T, Kadowaki S, Seto T, Masaki K, Edmundowicz D, Ueshima H, Kuller LH, Sekikawa A, Significant inverse associations of serum n-6 fatty acids with plasma plasminogen activator inhibitor-1. Br J Nutr 107:4(567-72)2012 Feb

21757663. Sekikawa A, Kadowaki T, El-Saed A, Okamura T, Sutton-Tyrrell K, Nakamura Y, Evans RW, Mitsunami K, Edmundowicz D, Nishio Y, Nakata K, Kadota A, Otake T, Miura K, Choo J, Abbott RD, Kuller LH, Curb JD, Ueshima H, Differential association of docosahexaenoic and eicosapentaenoic acids with carotid intima-media thickness. Stroke 42:9(2538-43)2011 Sep

21494228. Kuller LH, Pettee Gabriel KK, Kinzel LS, Underwood DA, Conroy MB, Chang Y, Mackey RH, Edmundowicz D, Tyrrell KS, Buhari AM, Kriska AM, The Women on the Move Through Activity and Nutrition (WOMAN) study: final 48-month results. Obesity (Silver Spring) 20:3(636-43)2012 Mar

21471825. El Khoudary SR, Wildman RP, Matthews K, Powell L, Hollenberg SM, Edmundowicz D, Sutton-Tyrrell K, Effect modification of obesity on associations between endogenous steroid sex hormones and arterial calcification in women at midlife. Menopause 18:8(906-14)2011 Aug

20821938. Azuma RW, Kadowaki T, El-Saed A, Ueshima H, Sutton-Tyrrell K, Nakamura Y, Edmundowicz D, Ueno Y, Evans RW, Kadota A, Kuller LH, Murata K, Takamiya T, Kadowaki S, Curb JD, Sekikawa A, Associations of D-dimer and von Willebrand factor with atherosclerosis in Japanese and white men. Acta Cardiol 65:4(449-56)2010 Aug

20668281. Matthews KA, Chang YF, Sutton-Tyrrell K, Edmundowicz D, Bromberger JT, Recurrent major depression predicts progression of coronary calcification in healthy women: Study of Women's Health Across the Nation. Psychosom Med 72:8(742-7)2010 Oct

20626294. Sekikawa A, Kadowaki T, Curb JD, Evans RW, Maegawa H, Abbott RD, Sutton-Tyrrell K, Okamura T, Shin C, Edmundowicz D, Kadota A, Choo J, El-Saed A, Ueshima H, Kuller LH, Circulating levels of 8 cytokines and marine n-3 fatty acids and indices of obesity in Japanese, white, and Japanese American middle-aged men. J Interferon Cytokine Res 30:7(541-8)2010 Jul

20580038. Nakata K, Choo J, Hopson MJ, Ueshima H, Curb JD, Shin C, Evans RW, Kadowaki T, Otake T, Kadota A, Kadowaki S, Miura K, El-Saed A, Edmundowicz D, Sutton-Tyrrell K, Kuller LH, Sekikawa A, Stronger associations of sagittal abdominal diameter with atherogenic lipoprotein subfractions than waist circumference in middle-aged US white and Japanese men. Metabolism 59:12(1742-51)2010 Dec

20042895. Thurston RC, Kuller LH, Edmundowicz D, Matthews KA, History of hot flashes and aortic calcification among postmenopausal women. Menopause 17:2(256-61)2010 Mar

19570556. Conway B, Evans RW, Fried L, Kelsey S, Edmundowicz D, Orchard TJ, Free fatty acids are associated with pulse pressure in women, but not men, with type 1 diabetes mellitus. Metabolism 58:9(1215-21)2009 Sep

19474136. Motoyama KR, Curb JD, Kadowaki T, El-Saed A, Abbott RD, Okamura T, Evans RW, Nakamura Y, Sutton-Tyrrell K, Rodriquez BL, Kadota A, Edmundowicz D, Willcox BJ, Choo J, Katsumi N, Otake T, Kadowaki S, Kuller LH, Ueshima H, Sekikawa A, Association of serum n-6 and n-3 polyunsaturated fatty acids with lipids in 3 populations of middle-aged men. Am J Clin Nutr 90:1(49-55)2009 Jul

19428036. Azuma K, Kadowaki T, Cetinel C, Kadota A, El-Saed A, Kadowaki S, Edmundowicz D, Nishio Y, Sutton-Tyrrell K, Okamura T, Evans RW, Takamiya T, Ueshima H, Curb JD, Abbott RD, Kuller LH, Kelley DE, Sekikawa A, Higher liver fat content among Japanese in Japan compared with non-Hispanic whites in the United States. Metabolism 58:8(1200-7)2009 Aug

19286698. Greco CM, Kao AH, Sattar A, Danchenko N, Maksimowicz-McKinnon KM, Edmundowicz D, Sutton-Tyrrell K, Tracy RP, Kuller LH, Manzi S, Association between depression and coronary artery calcification in women with systemic lupus erythematosus. Rheumatology (Oxford) 48:5(576-81)2009 May

21291774. Mulukutla SR, Venkitachalam L, Marroquin OC, Kip KE, Aiyer A, Edmundowicz D, Ganesh S, Varghese R, Reis SE, Population variations in atherogenic dyslipidemia: A report from the HeartSCORE and IndiaSCORE Studies. J Clin Lipidol 2:6(410-7)2008 Dec

18774002. Kao AH, Wasko MC, Krishnaswami S, Wagner J, Edmundowicz D, Shaw P, Cunningham AL, Danchenko N, Sutton-Tyrrell K, Tracy RP, Kuller LH, Manzi S, C-reactive protein and coronary artery calcium in asymptomatic women with systemic lupus erythematosus or rheumatoid arthritis. Am J Cardiol 102:6(755-60)2008 Sep 15

18672160. Sekikawa A, Curb JD, Ueshima H, El-Saed A, Kadowaki T, Abbott RD, Evans RW, Rodriguez BL, Okamura T, Sutton-Tyrrell K, Nakamura Y, Masaki K, Edmundowicz D, Kashiwagi A, Willcox BJ, Takamiya T, Mitsunami K, Seto TB, Murata K, White RL, Kuller LH, Marine-derived n-3 fatty acids and atherosclerosis in Japanese, Japanese-American, and white men: a cross-sectional study. J Am Coll Cardiol 52:6(417-24)2008 Aug 5

18289547. Kuller LH, Matthews KA, Edmundowicz D, Chang Y, Incident coronary artery calcium among postmenopausal women. Atherosclerosis 200:2(278-85)2008 Oct

18204407. Thurston RC, Sowers MR, Sutton-Tyrrell K, Everson-Rose SA, Lewis TT, Edmundowicz D, Matthews KA, Abdominal adiposity and hot flashes among midlife women. Menopause 15:3(429-34)2008 May-Jun

18191046. Sekikawa A, Ueshima H, Sutton-Tyrrell K, Kadowaki T, El-Saed A, Okamura T, Takamiya T, Ueno Y, Evans RW, Nakamura Y, Edmundowicz D, Kashiwagi A, Maegawa H, Kuller LH, Intima-media thickness of the carotid artery and the distribution of lipoprotein subclasses in men aged 40 to 49 years between whites in the United States and the Japanese in Japan for the ERA JUMP study. Metabolism 57:2(177-82)2008 Feb

18158704. Conway B, Miller RG, Costacou T, Fried L, Kelsey S, Evans RW, Edmundowicz D, Orchard TJ, Double-edged relationship between adiposity and coronary artery calcification in type 1 diabetes. Diab Vasc Dis Res 4:4(332-9)2007 Dec

18050383. Kao AH, Krishnaswami S, Cunningham A, Edmundowicz D, Morel PA, Kuller LH, Wasko MC, Subclinical coronary artery calcification and relationship to disease duration in women with rheumatoid arthritis. J Rheumatol 35:1(61-9)2008 Jan

18008040. Refaat M, Smith AJ, Edmundowicz D, Eptifibatide-induced thrombocytopenia. J Thromb Thrombolysis 25:2(204-6)2008 Apr

17996516. Costacou T, Edmundowicz D, Prince C, Conway B, Orchard TJ, Progression of coronary artery calcium in type 1 diabetes mellitus. Am J Cardiol 100:10(1543-7)2007 Nov 15

17688929. Matthews KA, Kuller LH, Chang Y, Edmundowicz D, Premenopausal risk factors for coronary and aortic calcification: a 20-year follow-up in the healthy women study. Prev Med 45:4(302-8)2007 Oct

17502042. Elliott JR, Manzi S, Edmundowicz D, The role of preventive cardiology in systemic lupus erythematosus. Curr Rheumatol Rep 9:2(125-30)2007 May

17244636. Sekikawa A, Ueshima H, Kadowaki T, El-Saed A, Okamura T, Takamiya T, Kashiwagi A, Edmundowicz D, Murata K, Sutton-Tyrrell K, Maegawa H, Evans RW, Kita Y, Kuller LH, Less subclinical atherosclerosis in Japanese men in Japan than in White men in the United States in the post-World War II birth cohort. Am J Epidemiol 165:6(617-24)2007 Mar 15

17239697. Aiyer AN, Kip KE, Marroquin OC, Mulukutla SR, Edmundowicz D, Reis SE, Racial differences in coronary artery calcification are not attributed to differences in lipoprotein particle sizes: the Heart Strategies Concentrating on Risk Evaluation (Heart SCORE) Study. Am Heart J 153:2(328-34)2007 Feb

17142145. Costacou T, Huskey ND, Edmundowicz D, Stolk R, Orchard TJ, Lower-extremity arterial calcification as a correlate of coronary artery calcification. Metabolism 55:12(1689-96)2006 Dec

17070140. Orakzai SH, Orakzai RH, Nasir K, Santos RD, Edmundowicz D, Budoff MJ, Blumenthal RS, Subclinical coronary atherosclerosis: racial profiling is necessary! Am Heart J 152:5(819-27)2006 Nov

17002567. Farhat GN, Cauley JA, Matthews KA, Newman AB, Johnston J, Mackey R, Edmundowicz D, Sutton-Tyrrell K, Volumetric BMD and vascular calcification in middle-aged women: the Study of Women's Health Across the Nation. J Bone Miner Res 21:12(1839-46)2006 Dec

16738064. Matthews KA, Owens JF, Edmundowicz D, Lee L, Kuller LH, Positive and negative attributes and risk for coronary and aortic calcification in healthy women. Psychosom Med 68:3(355-61)2006 May-Jun

16046367. Gianaros PJ, Salomon K, Zhou F, Owens JF, Edmundowicz D, Kuller LH, Matthews KA, A greater reduction in high-frequency heart rate variability to a psychological stressor is associated with subclinical coronary and aortic calcification in postmenopausal women. Psychosom Med 67:4(553-60)2005 Jul-Aug

15956001. Agatisa PK, Matthews KA, Bromberger JT, Edmundowicz D, Chang YF, Sutton-Tyrrell K, Coronary and aortic calcification in women with a history of major depression. Arch Intern Med 165:11(1229-36)2005 Jun 13

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