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Nae Dun, PhDNae Dun, PhD

 

Chairperson, Department of Pharmacology

Professor, Pharmacology

Telephone:  215-707- 3498

FAX: 215-707-7068

Email: nae.dun@temple.edu

 

Department of Pharmacology

 

Educational Background:

 

B.Sc., University of Illinois 1969

 

Ph.D. Loyola University Chicago, 1975

 

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Research Interests:

 

Brain recording

 

The goal of our research program is to identify the neural substrate involved in the regulation of blood pressure and heart rate. Our current research focuses on the identification and characterization of novel ligands and receptors, and neural circuitry relevant to control of circulation.    

 

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PUBMED PUBLICATIONS :


Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

19620632. Brailoiu E, Churamani D, Cai X, Schrlau MG, Brailoiu GC, Gao X, Hooper R, Boulware MJ, Dun NJ, Marchant JS, Patel S, Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. J Cell Biol 186:2(201-9)2009 Jul 27

19549515. Inan S, Dun NJ, Cowan A, Inhibitory effect of lidocaine on pain and itch using formalin-induced nociception and 5'-guanidinonaltrindole-induced scratching models in mice: behavioral and neuroanatomical evidence. Eur J Pharmacol 616:1-3(141-6)2009 Aug 15

19524022. Inan S, Dun NJ, Cowan A, Nalfurafine prevents 5'-guanidinonaltrindole- and compound 48/80-induced spinal c-fos expression and attenuates 5'-guanidinonaltrindole-elicited scratching behavior in mice. Neuroscience 163:1(23-33)2009 Sep 29

19373968. Brailoiu E, Dun SL, Gao X, Brailoiu GC, Li JG, Luo JJ, Yang J, Chang JK, Liu-Chen LY, Dun NJ, C-peptide of preproinsulin-like peptide 7: localization in the rat brain and activity in vitro. Neuroscience 159:2(492-500)2009 Mar 17

19125412. Dun SL, Brailoiu GC, Gao X, Brailoiu E, Arterburn JB, Prossnitz ER, Oprea TI, Dun NJ, Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia. J Neurosci Res 87:7(1610-9)2009 May 15

19090786. Brailoiu GC, Brailoiu E, Parkesh R, Galione A, Churchill GC, Patel S, Dun NJ, NAADP-mediated channel 'chatter' in neurons of the rat medulla oblongata. Biochem J 419:1(91-7, 2 p following 97)2009 Apr 1

18752653. Gao X, Brailoiu GC, Brailoiu E, Dun SL, Yang J, Chang JK, Dun NJ, Copeptin immunoreactivity and calcium mobilisation in hypothalamic neurones of the rat. J Neuroendocrinol 20:11(1242-51)2008 Nov

18404520. Tuluc F, Bredetean O, Brailoiu E, Meshki J, Garcia A, Dun NJ, Kunapuli SP, The priming effect of extracellular UTP on human neutrophils: Role of calcium released from thapsigargin-sensitive intracellular stores. Purinergic Signal 1:4(359-68)2005 Dec

18375741. Ji R, Lee CM, Gonzales LW, Yang Y, Aksoy MO, Wang P, Brailoiu E, Dun N, Hurford MT, Kelsen SG, Human type II pneumocyte chemotactic responses to CXCR3 activation are mediated by splice variant A. Am J Physiol Lung Cell Mol Physiol 294:6(L1187-96)2008 Jun

18314227. Brailoiu E, Jiang X, Brailoiu GC, Yang J, Chang JK, Wang H, Dun NJ, State-dependent calcium mobilization by urotensin-II in cultured human endothelial cells. Peptides 29:5(721-6)2008 May

18164555. Brailoiu GC, Brailoiu E, Chang JK, Dun NJ, Excitatory effects of human immunodeficiency virus 1 Tat on cultured rat cerebral cortical neurons. Neuroscience 151:3(701-10)2008 Feb 6

17715404. Jiang X, Yang F, Brailoiu E, Jakubowski H, Dun NJ, Schafer AI, Yang X, Durante W, Wang H, Differential regulation of homocysteine transport in vascular endothelial and smooth muscle cells. Arterioscler Thromb Vasc Biol 27:9(1976-83)2007 Sep

17627999. Brailoiu GC, Dun SL, Brailoiu E, Inan S, Yang J, Chang JK, Dun NJ, Nesfatin-1: distribution and interaction with a G protein-coupled receptor in the rat brain. Endocrinology 148:10(5088-94)2007 Oct

17470522. Brailoiu E, Dun SL, Brailoiu GC, Mizuo K, Sklar LA, Oprea TI, Prossnitz ER, Dun NJ, Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. J Endocrinol 193:2(311-21)2007 May

17465030. Brailoiu GC, Dun SL, Mizuo K, Brailoiu E, Yang J, Chang JK, Dun NJ, Smooth muscle-associated protein 8: distribution and biological activity in the rat brain. J Neurosci Res 85:8(1789-96)2007 Jun

17187876. Dun SL, Brailoiu E, Hsieh WK, Lai CC, Yang J, Chang JK, Dun NJ, Expression and activity of cocaine- and amphetamine-regulated transcript peptide(1-39) in the rat. Regul Pept 140:1-2(47-54)2007 Apr 5

17088418. Dun SL, Brailoiu GC, Brailoiu E, Yang J, Chang JK, Dun NJ, Distribution and biological activity of obestatin in the rat. J Endocrinol 191:2(481-9)2006 Nov

16707193. Dun SL, Brailoiu GC, Yang J, Chang JK, Dun NJ, Cocaine- and amphetamine-regulated transcript peptide and sympatho-adrenal axis. Peptides 27:8(1949-55)2006 Aug

16650615. Wang Y, Dun SL, Huang P, Chen C, Chen Y, Unterwald EM, Dun NJ, Van Bockstaele EJ, Liu-Chen LY, Distribution and ultrastructural localization of GEC1 in the rat CNS. Neuroscience 140:4(1265-76)2006 Jul 21

16601133. Dun SL, Brailoiu E, Wang Y, Brailoiu GC, Liu-Chen LY, Yang J, Chang JK, Dun NJ, Insulin-like peptide 5: expression in the mouse brain and mobilization of calcium. Endocrinology 147:7(3243-8)2006 Jul

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