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Verdi J. DiSesa, MD, MBA

Professor, Surgery

Vice Dean for Clinical Affairs, Temple University School of Medicine

Chief Operating Officer, Temple University Health System

Telephone:  215-707-8828

Email: verdi.disesa@tuhs.temple.edu

Department of Surgery, Section of Cardiovascular Surgery

MD, University of Pennsylvania School of Medicine, Philadelphia, PA

 

Residency, Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA

 

Residency, Surgery, Brigham and Women's Hospital, Boston, MA

 

Residency, Cardiothoracic Surgery, Brigham and Women's Hospital, Boston, MA

 

Cardiovascular Surgery, Children's Hospital, Boston, MA

 

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• Integrated disease management
• Treatment of valvular heart disease
• Transplant biology

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• Internal medicine
• Surgery
• Thoracic and cardiac surgery

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• Fellow, American College of Cardiology
• Fellow, American College of Chest Physicians
• Fellow, American College of Surgeons
• Fellow, American Surgical Association
• Member, American Association of Immunologists
• Member, American College of Healthcare Executives
• Member, Association for Academic Surgery

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• Cardiac transplantation
• Cardiac xenotransplantation

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

22172748. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, DiSesa VJ, Hiratzka LF, Hutter AM Jr, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD, Jacobs AK, Anderson JL, Albert N, Creager MA, Ettinger SM, Guyton RA, Halperin JL, Hochman JS, Kushner FG, Ohman EM, Stevenson W, Yancy CW, 2011 ACCF/AHA guideline for coronary artery bypass graft surgery: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Thorac Cardiovasc Surg 143:1(4-34)2012 Jan

22127814. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, DiSesa VJ, Hiratzka LF, Hutter AM Jr, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD, Special Articles: 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Anesth Analg 114:1(11-45)2012 Jan

22070836. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, Disesa VJ, Hiratzka LF, Hutter AM Jr, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD, 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Developed in collaboration with the American Association for Thoracic Surgery, Society of Cardiovascular Anesthesiologists, and Society of Thoracic Surgeons. J Am Coll Cardiol 58:24(e123-210)2011 Dec 6

22064600. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, Disesa VJ, Hiratzka LF, Hutter AM Jr, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD, 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 124:23(2610-42)2011 Dec 6

22064599. Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, Disesa VJ, Hiratzka LF, Hutter AM Jr, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD, 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 124:23(e652-735)2011 Dec 6

21502460. Whitman GJ, DiSesa VJ, Transfusions in cardiac surgery. Arch Surg 146:4(481-2)2011 Apr

17184623. Smith PK, Mayer JE Jr, Kanter KR, DiSesa VJ, Levett JM, Wright CD, Nichols FC 3rd, Naunheim KS, Physician payment for 2007: a description of the process by which major changes in valuation of cardiothoracic surgical procedures occurred. Ann Thorac Surg 83:1(12-20)2007 Jan

17075012. DiSesa VJ, O'Brien SM, Welke KF, Beland SM, Haan CK, Vaughan-Sarrazin MS, Peterson ED, Contemporary impact of state certificate-of-need regulations for cardiac surgery: an analysis using the Society of Thoracic Surgeons' National Cardiac Surgery Database. Circulation 114:20(2122-9)2006 Nov 14

16305902. DiSesa VJ, Invited commentary. Ann Thorac Surg 80:6(2337)2005 Dec

14992909. Aylsworth CL, Stefan F, Woitas K, Rieger RH, LeBoutillier M 3rd, DiSesa VJ, New technology, old standards: disparate activated clotting time measurements by the Hemochron Jr compared with the standard Hemochron. Ann Thorac Surg 77:3(973-6)2004 Mar

12645700. Savage EB, Ferguson TB Jr, DiSesa VJ, Use of mitral valve repair: analysis of contemporary United States experience reported to the Society of Thoracic Surgeons National Cardiac Database. Ann Thorac Surg 75:3(820-5)2003 Mar

12490793. Tanemura M, Chong AS, DiSesa VJ, Galili U, Direct killing of xenograft cells by CD8+ T cells of discordant xenograft recipients. Transplantation 74:11(1587-95)2002 Dec 15

12196325. Platt J, DiSesa V, Gail D, Massicot-Fisher J, Recommendations of the National Heart, Lung, and Blood Institute Heart and Lung Xenotransplantation Working Group. Circulation 106:9(1043-7)2002 Aug 27

12131678. Tanemura M, Ogawa H, Yin DP, Chen ZC, DiSesa VJ, Galili U, Elimination of anti-Gal B cells by alpha-Gal ricin1. Transplantation 73:12(1859-68)2002 Jun 27

11565651. Mohiuddin MM, Qin Y, Qian X, Meng Y, DiSesa VJ, Long-term survival of cardiac xenografts in fully xenogeneic (mouse --> rat) bone marrow chimeras. Ann Thorac Surg 72:3(740-5; discussion 745-6)2001 Sep

11267025. Tanemura M, Yin D, DiSesa VJ, Galili U, Preventing anti-Gal response in xenograft recipients by an alpha-Gal toxin. Transplant Proc 33:1-2(699-700)2001 Feb-Mar

11235756. DiSesa VJ, Mohiuddin MM, As originally published in 1994: Development of tolerance to experimental cardiac allograft in utero. Updated in 2001. Ann Thorac Surg 71:2(755-6)2001 Feb

10755518. Mohiuddin MM, Ildstad ST, DiSesa VJ, Establishment of fully xenogeneic (mouse-->rat) bone marrow chimeras: evidence for normal development and clonal deletion of mouse T cells. Transplantation 69:5(731-6)2000 Mar 15

11054236. Madan AK, Santora TA, Disesa VJ, Extra-anatomic bypass grafting for aortoesophageal fistula: a logical operation. J Vasc Surg 32:5(1030-3)2000 Nov

10936341. Mohiuddin MM, Qian X, Qin Y, DiSesa VJ, Partial deletion of donor T cells in the recipient thymus in fully xenogeneic mouse-to-rat chimeras. Transplant Proc 32:5(1039)2000 Aug

10936334. Mohiuddin MM, Qian X, Qin Y, DiSesa VJ, Multilineage bone marrow chimerism produces cellular and humoral tolerance in a mouse-to-rat cardiac xenograft. Transplant Proc 32:5(1029-30)2000 Aug

10936286. Mohiuddin MM, Qian X, Qin Y, DiSesa VJ, Avoidance of graft versus host disease by proper titration of cell and radiation dose in a mouse to rat xeno-chimera. Transplant Proc 32:5(943)2000 Aug

10083364. Mohiuddin MM, Yokoyama H, Reiss GR, DiSesa VJ, Induction of tolerance to an "untolerizable" strain by double-strain intrathymic inoculation in experimental rat cardiac transplantation. Transplant Proc 31:1-2(838-9)1999 Feb-Mar

10080968. Winkel E, DiSesa VJ, Costanzo MR, Advances in heart transplantation. Dis Mon 45:3(62-87)1999 Mar

9857872. Kimmel SE, Sekeres MA, Berlin JA, Ellison N, DiSesa VJ, Strom BL, Risk factors for clinically important adverse events after protamine administration following cardiopulmonary bypass. J Am Coll Cardiol 32:7(1916-22)1998 Dec

9436597. DiSesa VJ, Cardiac xenotransplantation. Ann Thorac Surg 64:6(1858-65)1997 Dec

8970604. Yokoyama H, Momeni R, Goldstein C, Mohiuddin M, Shen Z, Fyfe BS, Whitman GJ, DiSesa VJ, Effects of vesnarinone, a novel orally active inotropic agent with an immunosuppressive action, on experimental cardiac transplantation in rats. Transplantation 62:11(1540-3)1996 Dec 15

8911329. Shen Z, Mohiuddin M, Yokoyama H, Reiss GR, DiSesa VJ, Induction of tolerance to an experimental cardiac allograft through intrathymic inoculation of class II major histocompatibility complex disparate antigens. J Thorac Cardiovasc Surg 112:5(1315-8)1996 Nov

8893569. Shen Z, Mohiuddin M, DiSesa VJ, Fetal inoculation with donor cells in cardiac xenotransplantation. Ann Thorac Surg 62:5(1360-3)1996 Nov

8913921. Shen Z, Pelletier S, Mohiuddin M, Yokoyama H, Reiss GR, DiSesa VJ, Different immune effects on cardiac allografts and xenografts induced by neonatal intrathymic inoculation with allogeneic and xenogeneic antigens. J Heart Lung Transplant 15:10(1034-8)1996 Oct

8751496. Mohiuddin M, Ruggiero V, Shen Z, DiSesa VJ, T-cell receptor expression in C57BL/6 mice that reject or are rendered tolerant to bm1 cardiac grafts. J Thorac Cardiovasc Surg 112:2(310-3)1996 Aug

8661177. Goldstein C, Reiss GR, Mohiuddin M, Shen Z, Yokoyama H, DiSesa VJ, Tolerance to cardiac allografts requires a time lag between intrathymic treatment and transplantation. J Surg Res 63:1(83-5)1996 Jun

8623363. Shen Z, Mohiuddin M, Goldstein C, Yokoyama H, DiSesa VJ, Tolerance to experimental cardiac allografts but not xenografts is induced after simultaneous neonatal intrathymic inoculation with allo and xenogeneic cells. Transplant Proc 28:2(719-20)1996 Apr

8623337. Mohiuddin M, Shen Z, Goldstein C, Yokoyama H, DiSesa VJ, Experimental cardiac xenografting with irradiation and intrathymic and intravenous xenogeneic cells. Transplant Proc 28:2(673)1996 Apr

8583817. Shen Z, Mohiuddin M, Goldstein C, Yokoyama H, DiSesa VJ, Durability of donor-specific and organ-specific heart transplant tolerance induced by intrathymic pretreatment with allogeneic spleen cells. J Thorac Cardiovasc Surg 111:2(429-31)1996 Feb

8787463. Shen Z, Mohiuddin M, DiSesa VJ, Suppressor cells and intrathymic inoculation of donor alloantigens in cardiac transplantation. Ann Thorac Surg 60:6(1683-5)1995 Dec

8526657. Cohn LH, Kowalker W, Bhatia S, DiSesa VJ, St John-Sutton M, Shemin RJ, Collins JJ, Comparative morbidity of mitral valve repair versus replacement for mitral regurgitation with and without coronary artery disease. 1988. Updated in 1995. Ann Thorac Surg 60:5(1452-3)1995 Nov

7818334. McFarland JJ, Kahn MB, Bellows CF, Shah RM, Koenigsberg RA, Parsons RE, Whitman GJ, DiSesa VJ, Superior vena cava syndrome caused by aneurysm of the innominate artery. Ann Thorac Surg 59:1(227-9)1995 Jan

7979653. Kline GM, Shen Z, Mohiuddin M, Rostami S, DiSesa VJ, Tolerance to experimental cardiac allografts produced by neonatal intrathymic injection of donor cells. Ann Thorac Surg 58:5(1316-8; discussion 1318-9)1994 Nov

7944748. DiSesa VJ, Mull R, Daly ES, Edmunds LH Jr, Mancini DM, Eisen HJ, Cardiac transplant donor heart allocation based on prospective tissue matching. Ann Thorac Surg 58:4(1050-3)1994 Oct

8196391. Shen Z, Kline G, Mohiuddin M, DiSesa VJ, Histocompatibility differences and cardiac transplant tolerance produced by intrathymic pretreatment. J Thorac Cardiovasc Surg 107:6(1472-5)1994 Jun

8029916. Mohiuddin M, Shen Z, Rostami S, DiSesa VJ, Experiments in cardiac xenotransplantation: fetal and neonatal exposure of graft recipients to xenogeneic cells. Transplant Proc 26:3(1306-7)1994 Jun

8176988. Gold JP, Shemin RJ, DiSesa VJ, Cohn LH, Collins JJ Jr, Triple sequential grafts using the internal mammary artery: an angiographic and short-term follow-up study. J Thorac Cardiovasc Surg 107:5(1377-8)1994 May

8166535. Edmunds LH Jr, Herrmann HC, DiSesa VJ, Ratcliffe MB, Bavaria JE, McCarthy DM, Left ventricular assist without thoracotomy: clinical experience with the Dennis method. Ann Thorac Surg 57:4(880-5)1994 Apr

8304361. Lee AH, Mull RL, Keenan GF, Callegari PE, Dalinka MK, Eisen HJ, Mancini DM, DiSesa VJ, Attie MF, Osteoporosis and bone morbidity in cardiac transplant recipients. Am J Med 96:1(35-41)1994 Jan

8279922. Kline GM, Shen Z, Mohiuddin M, Ruggiero V, Rostami S, DiSesa VJ, Development of tolerance to experimental cardiac allografts in utero. Ann Thorac Surg 57:1(72-4; discussion 75)1994 Jan

8018147. Hanna AK, DiSesa VJ, Reversal of cardiac allograft rejection without immunotherapy: an animal model. Ann Thorac Surg 56:6(1335-8)1993 Dec

8412256. Mohiuddin M, Kline G, Shen Z, Ruggiero V, Rostami S, DiSesa VJ, Experiments in cardiac xenotransplantation. Response to intrathymic xenogeneic cells and intravenous cobra venom factor. J Thorac Cardiovasc Surg 106:4(632-5)1993 Oct

8412072. Hanna AK, Miller J, Liang BT, DiSesa VJ, Reversible contractile dysfunction in reversible experimental cardiac allograft rejection: alterations in the beta-receptor-stimulated adenylylcyclase pathway. J Surg Res 54:6(610-5)1993 Jun

8329408. Kline GM, Shen Z, Mohiuddin M, Ruggiero V, Rostami S, DiSesa VJ, Successful experimental heart transplantation without immunosuppressive drugs. J Heart Lung Transplant 12:3(388-93)1993 May-Jun

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