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Philip L. Cohen, MD

Section Chief, Rheumatology

Professor, Medicine

Telephone:  215-707-0791

FAX: 215-707-3508

Email: philco@temple.edu

Department of Medicine, Section of Rheumatology

 

BS, City College of New York, New York City, NY, 1968

 

MD, Yale University School of Medicine, New Haven, CT, 1972

 

Internship, Columbia-Presbyterian Medical Center, New York City, NY, 1972-1973

 

Research Associate, Laboratory of Immunology, NIAID, 1973-1975

 

Residency, Columbia-Presbyterian Medical Center, New York City, NY, 1975-1976

 

Fellowship, Rheumatology, University of Texas Southwestern Medical Center, Dallas, TX, 1976-1978

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• Systemic lupus

• Sjögren's syndrome
• Rheumatoid arthritis

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• Systemic autoimmunity
• Apoptosis and its disorders

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• Internal Medicine, 1977
• Rheumatology, 1978

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• American Association of Immunologists
• American College of Rheumatology
• American Society for Clinical Investigation
• College of Physicians of Philadelphia
• Philadelphia Rheumatism Association

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

19631584. Shao WH, Zhen Y, Eisenberg RA, Cohen PL, The Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells. Clin Immunol 133:1(138-44)2009 Oct

19542457. Yunk L, Meng W, Cohen PL, Eisenberg RA, Luning Prak ET, Antibodies in a heavy chain knock-in mouse exhibit characteristics of early heavy chain rearrangement. J Immunol 183:1(452-61)2009 Jul 1

19017966. Tsao PY, Jiao J, Ji MQ, Cohen PL, Eisenberg RA, T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice. J Immunol 181:11(7770-7)2008 Dec 1

18713966. Li Y, Chen F, Putt M, Koo YK, Madaio M, Cambier JC, Cohen PL, Eisenberg RA, B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice. J Immunol 181:5(2961-72)2008 Sep 1

18490777. Shao WH, Eisenberg RA, Cohen PL, The Mer receptor tyrosine kinase is required for the loss of B cell tolerance in the chronic graft-versus-host disease model of systemic lupus erythematosus. J Immunol 180:11(7728-35)2008 Jun 1

18467644. Ait-Oufella H, Pouresmail V, Simon T, Blanc-Brude O, Kinugawa K, Merval R, Offenstadt G, Lesèche G, Cohen PL, Tedgui A, Mallat Z, Defective mer receptor tyrosine kinase signaling in bone marrow cells promotes apoptotic cell accumulation and accelerates atherosclerosis. Arterioscler Thromb Vasc Biol 28:8(1429-31)2008 Aug

18432900. Cohen PL, Maldonado MA, Animal models for SLE. Curr Protoc Immunol Chapter 15:(Unit 15.20)2003 Feb

18325838. Ma Z, Choudhury A, Kang SA, Monestier M, Cohen PL, Eisenberg RA, Accelerated atherosclerosis in ApoE deficient lupus mouse models. Clin Immunol 127:2(168-75)2008 May

17911643. Choudhury A, Cohen PL, Eisenberg RA, Mature B cells preferentially lose tolerance in the chronic graft-versus-host disease model of systemic lupus erythematosus. J Immunol 179:8(5564-70)2007 Oct 15

17082664. Ma Z, Chen F, Madaio MP, Cohen PL, Eisenberg RA, Modulation of autoimmunity by TLR9 in the chronic graft-vs-host model of systemic lupus erythematosus. J Immunol 177:10(7444-50)2006 Nov 15

16941106. Cohen PL, Apoptotic cell death and lupus. Springer Semin Immunopathol 28:2(145-52)2006 Oct

16572440. Cohen PL, Stopping traffic in Sjögren's syndrome. Arthritis Rheum 54:4(1061-2)2006 Apr

16277689. Carl PL, Temple BR, Cohen PL, Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity. Arthritis Res Ther 7:6(R1360-74)2005

15944260. Choudhury A, Maldonado MA, Cohen PL, Eisenberg RA, The role of host CD4 T cells in the pathogenesis of the chronic graft-versus-host model of systemic lupus erythematosus. J Immunol 174:12(7600-9)2005 Jun 15

15789337. Kuan AP, Cohen PL, p53 is required for spontaneous autoantibody production in B6/lpr lupus mice. Eur J Immunol 35:5(1653-60)2005 May

15261337. Cohen PL, Caricchio R, Genetic models for the clearance of apoptotic cells. Rheum Dis Clin North Am 30:3(473-86, viii)2004 Aug

14993405. Cohen PL, Autoimmunity and lymphoproliferation: two genes are worse than one. Mol Interv 2:7(427-30)2002 Nov

14872521. Cohen PL, Self-arthrocentesis in a man with joint pain. Arthritis Rheum 50:2(680)2004 Feb

14634086. Caricchio R, McPhie L, Cohen PL, Ultraviolet B radiation-induced cell death: critical role of ultraviolet dose in inflammation and lupus autoantigen redistribution. J Immunol 171:11(5778-86)2003 Dec 1

12884290. Behrens EM, Gadue P, Gong SY, Garrett S, Stein PL, Cohen PL, The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity. Eur J Immunol 33:8(2160-7)2003 Aug

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