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Tinatin Chabrashvili, MD, PhD

Assistant Professor, Neurology

Telephone:  215-707-9738

FAX: 215-707-8235

Email: tinatin.chabrashvili@tuhs.temple.edu

Department of Neurology

MD, Tbilisi State Medical School, Tbilisi, Georgia

 

PhD, Neuroscience, Institute of Neurology, Russian Academy of Medical Science, Moscow, Russia

 

Residency, Neurology, Institute of Neurology, Russian Academy of Medical Science, Moscow, Russia

 

Residency, Neurology, Emory University, Atlanta, GA

 

Fellowship, Clinical Neurogenetic Unit, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD

 

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• Prevention and treatment of neurodegenerative disease
• Special emphasis on movement disorders
• Blood-brain barrier permeability
• Neurovascular care

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American Board of Neurology

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• Oxidative stress and hypertension
• Sallie Mae Young Investigator Award, 2002
• AstraZeneca Sixth Annual Young Cardiovascular Investigator's Award, 2000

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Recent Medically Related Publications, Obtained from PubMed (Click on PubMed ID to view abstract)

17673667. Wang D, Gill PS, Chabrashvili T, Onozato ML, Raggio J, Mendonca M, Dennehy K, Li M, Modlinger P, Leiper J, Vallance P, Adler O, Leone A, Tojo A, Welch WJ, Wilcox CS, Isoform-specific regulation by N(G),N(G)-dimethylarginine dimethylaminohydrolase of rat serum asymmetric dimethylarginine and vascular endothelium-derived relaxing factor/NO. Circ Res 101:6(627-35)2007 Sep 14

17015770. Welch WJ, Chabrashvili T, Solis G, Chen Y, Gill PS, Aslam S, Wang X, Ji H, Sandberg K, Jose P, Wilcox CS, Role of extracellular superoxide dismutase in the mouse angiotensin slow pressor response. Hypertension 48:5(934-41)2006 Nov

16391171. Modlinger P, Chabrashvili T, Gill PS, Mendonca M, Harrison DG, Griendling KK, Li M, Raggio J, Wellstein A, Chen Y, Welch WJ, Wilcox CS, RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response. Hypertension 47:2(238-44)2006 Feb

16340215. Wang D, Chabrashvili T, Borrego L, Aslam S, Umans JG, Angiotensin II infusion alters vascular function in mouse resistance vessels: roles of O and endothelium. J Vasc Res 43:1(109-19)2006

15598867. Welch WJ, Blau J, Xie H, Chabrashvili T, Wilcox CS, Angiotensin-induced defects in renal oxygenation: role of oxidative stress. Am J Physiol Heart Circ Physiol 288:1(H22-8)2005 Jan

15117817. Wang D, Chabrashvili T, Wilcox CS, Enhanced contractility of renal afferent arterioles from angiotensin-infused rabbits: roles of oxidative stress, thromboxane prostanoid receptors, and endothelium. Circ Res 94:11(1436-42)2004 Jun 11

14569088. Wang D, Chen Y, Chabrashvili T, Aslam S, Borrego Conde LJ, Umans JG, Wilcox CS, Role of oxidative stress in endothelial dysfunction and enhanced responses to angiotensin II of afferent arterioles from rabbits infused with angiotensin II. J Am Soc Nephrol 14:11(2783-9)2003 Nov

14569087. Kitiyakara C, Chabrashvili T, Chen Y, Blau J, Karber A, Aslam S, Welch WJ, Wilcox CS, Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J Am Soc Nephrol 14:11(2775-82)2003 Nov

12609817. Chabrashvili T, Kitiyakara C, Blau J, Karber A, Aslam S, Welch WJ, Wilcox CS, Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression. Am J Physiol Regul Integr Comp Physiol 285:1(R117-24)2003 Jul

11847196. Chabrashvili T, Tojo A, Onozato ML, Kitiyakara C, Quinn MT, Fujita T, Welch WJ, Wilcox CS, Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney. Hypertension 39:2(269-74)2002 Feb

11247829. Kitiyakara C, Chabrashvili T, Jose P, Welch WJ, Wilcox CS, Effects of dietary salt intake on plasma arginine. Am J Physiol Regul Integr Comp Physiol 280:4(R1069-75)2001 Apr

8619528. Goldfarb LG, Vasconcelos O, Platonov FA, Lunkes A, Kipnis V, Kononova S, Chabrashvili T, Vladimirtsev VA, Alexeev VP, Gajdusek DC, Unstable triplet repeat and phenotypic variability of spinocerebellar ataxia type 1. Ann Neurol 39:4(500-6)1996 Apr

8647411. Illarioshkin SN, Ivanova-Smolenskaia IA, Markova ED, Nikol'skaia NN, Chabrashvili TZ, Insarova NG, [Analysis of trinucleotide repeat expansion as a new mechanism of mutation in Huntington's chorea: theoretical and applied aspects] Genetika 32:1(103-9)1996 Jan

7778395. Ivanova-Smolenskaia IA, Vereshchagin NV, Illarioshkin SN, Markova ED, Nikol'skaia NN, Chabrashvili TZ, Insarova NG, [Triplet expansion analysis--a new molecular genetic method for studying the mechanism of mutations in neurogenetics (exemplified by Huntington chorea)] Zh Nevrol Psikhiatr Im S S Korsakova 95:1(52-7)1995

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