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Comprehensive NeuroAIDS Center

COMPREHENSIVE NEUROAIDS CENTER (cnac)

 

Topic-Specific RFA: “Peripheral Neuropathy and NeuroAIDS”

The CNAC Developmental Core is interested in applications related to HIV-Related Peripheral Neuropathy, particularly applications utilizing human, animal, and/or in vitro studies. Please see full RFA for more details. If you have any questions, please contact andrea.albelda@temple.edu.

 

 

Developmental Core


This core provides an organization and structure that will effectively integrate mentorship and new project development with the utilization of the other cores to achieve the objectives of the Comprehensive NeuroAIDS Center (CNAC). This core provides financial support for novel and innovative studies that take the field of NeuroAIDS in new directions, in studies ranging from basic to translational/clinical studies. Through the letter of intent and application process, applicants are provided mentorship and guidance via interaction with relevant CNAC members and/or Core leaders in order to foster successful project and career development. While this mechanism of support is primarily designed for junior faculty, we encourage application from clinicians who would like to develop research programs, potentially in collaboration with a basic scientist, or from more senior researchers wishing to pursue novel research directions.


Since inception, the Developmental Core has funded 9 individual projects over two years:


2012:

  • “Role of Exosomes in NeuroAIDS” – Prasun Datta, Ph.D., Assistant Professor, Department of Neuroscience, Temple University School of Medicine
  • “Impact of HIV-1 Tat genetic variants on the blood-brain barrier” – Michael Nonnemacher, Ph.D., Assistant Professor, Department of Microbiology and Immunology, Drexel University College of Medicine
  • “Evaluating the efficacy of the Virtual Reality Supermarket task for predicting neurocognitive function in HIV-infected subjects” – Giuseppe Russo, Ph.D., Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University


2013:

  • “Metabolomics of macrophages overexpressing HIV-1 Vpr protein: A targeted Approach” – Carlos Barrero, M.D., Associate Scientist, Biochemistry Department, Temple University School of Medicine
  • “Transcriptomic Effects of Cannabinoids on HIV-1 Replication” – Mario Chin, Ph.D., Assistant Professor, Department of Microbiology and Immunology, Center for Substance Abuse Research, Temple University School of Medicine
  • “Exploring interplay of neuropathic axon degeneration, mitochondrial trafficking, and endogenous axon destruction mechanisms” – Toby Ferguson, M.D., Ph.D., Assistant Professor, Neurology Department, Shriners Hospitals Pediatric Research Center, Temple University School of Medicine
  • “Role of microbial translocation in altered plasma environment and CD16+ monocyte expansion in HIV” – Tracy Fischer-Smith, Ph.D., Assistant Professor, Department of Neuroscience, Temple University School of Medicine
  • “Interplay between microRNAs and HIV-1 in human microglia and astrocytes” – Julio Martin-Garcia, Ph.D., Associate Professor, Department of Microbiology and Immunology, Drexel University College of Medicine
  • “The relationship between resting state functional connectivity and neurocognitive function in HIV infected subjects: a pre and post cART perspective” – Erin O’Connor, M.D., Associate Professor, Department of Radiology, Temple University School of Medicine


Dr. Rappaport advises a graduate student. Photo by Ryan Brandenberg, Temple University.

 

Drs. Datta and Amini in consultation. Photo by Ryan Brandenberg, Temple University.