department of Neuroscience and center for neurovirology
Temple Researchers Successfully Eradicate HIV Virus in Human Cell Cultures
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A Message from Kamel Khalili, PhD
Chairperson, Department of Neuroscience
Director, Center for Neurovirology
Director, Comprehensive NeuroAIDS Center
Laura H. Carnell Professor, Neuroscience
In 2005, the Department of Neuroscience at the Temple University School of Medicine was established to perform multidisciplinary disease-oriented research in neuroscience and offer exemplary training programs for educating pre- and postdoctoral students and fellows in biomedical neuroscience.
The programs in the Department of Neuroscience are structured in four interdisciplinary research areas, including neurodegeneration, neuroinfection, neuroinflammation and neuromalignancy. To accomplish our goals we utilize a broad range of molecular and cellular approaches using in vitro cell culture systems and in vivo experimental animal models which are developed by our team. In parallel, we evaluate relevant clinical samples provided by our collaborators at Temple University Hospitals and other facilities. All of our research programs are transformative and aimed at understanding the molecular events involved in the development of neurological disorders including Alzheimer's disease, disorders associated with viral infection including HIV- and JCV-induced neural injury, demyelinating disorders including multiple sclerosis, and pediatric and adult brain tumors such as medulloblastoma and glioblastoma. Our goal is to utilize the laboratory findings for the development of biomarkers for early diagnosis, and safer and more effective therapeutic molecules toward the above-noted neurologic disorders.
The integration of the well-established Center for Neurovirology (CNV), with its excellent record of productivity in studying the pathogenesis of neurotropic viruses with the Department of Neuroscience offers a unique infrastructure for the development of multidisciplinary research strategies for studying a broad range of viral and non-viral associated neurologic disorders, and facilitates establishment of collaboration among various biomedical scientists and clinicians. CNV has played a central role in developing NIH funded Comprehensive NeuroAIDS Center (CNAC) facilities for promoting translational research in AIDS and neurological disorders.
Department of Neuroscience and Center for Neurovirology
Temple University School of Medicine
3500 North Broad Street
Medical Education and Research Building
Philadelphia, PA 19140