Santhi Potireddy is a doctoral student from Biochemistry department working at Dr.Latham's laboratory. She has an undergraduate degree in veterinary science from ANGRAU Agricultural University, Tirupati, AP in India. After completing the undergraduate degree, she joined Temple University in Fall 2003 and into Dr.Latham's lab in May 2004. She is presently working on maternal control of nuclear function in the early embryo, as related to two processes: embryonic genome activation and nuclear reprogramming in cloned embryos.

Most Recent Paper: Analysis of Polysomal mRNA populations of mouse oocytes and zygotes:Dynamic changes in maternal mRNA utilization and function. 2006

Abstract: Transcriptional activation in mammalian embryos occurs in a stepwise manner. In mice, it begins at the late one-cell stage, followed by a minor wave of activation at the early two-cell stage, and then the major genome activation event (MGA) at the late two-cell stage. Cellular homeostasis, metabolism, cell cycle, and developmental events are orchestrated before MGA by time-dependent changes in the array of maternal transcripts being translated........

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