Faculty & Staff

Sinclair Smith
Sc.D.

Sinclair A. Smith, Sc.D. received his BS in Biology and his MS in Exercise Physiology from Virginia Tech. and State University. His Doctorate of Science is in Applied Anatomy and Physiology from Boston University and his dissertation research examined the effects of aging, dehydration, and oral creatine supplementation on skeletal muscle metabolism using phosphorus magnetic resonance spectroscopy. Before coming to Temple, Dr. Smith worked as a research physiologist at the U.S. Army Research Institute of Environmental Medicine in Natick, Massachusetts and as an Assistant Professor at Belmont University in Nashville, Tennessee. He currently teaches courses in anatomy, kinesiology, physiology and research methods and he advises graduate student thesis/dissertation research. In
addition, he is the director of the Neuromuscular Function Laboratory in the Department of Occupational Therapy. His primary research interest is the use of non-invasive techniques to study neuromuscular metabolism and function in humans.

Neuromuscular Function Laboratory

Publications

McCully, K.K.,  S.A. Smith, S. Rajaei, J.S. Leigh, and B.H.Natelson: Muscle metabolism with blood flow restriction in chronic fatigue syndrome. Journal of Applied Physiology, (in review).

Smith, S.A., S.J. Montain, G.P. Zientara, and R.A. Fielding: Muscle creatine concentration influences mitochondrial respiration: An in vivo 31P MRS study of oral creatine ingestion. Journal of Applied Physiology, (in review).

McCully, K.K.,  S.A. Smith, S. Rajaei, J.S. Leigh, and B.H.Natelson: Blood flow and muscle metabolism in chronic fatigue syndrome. Clinical Science, 104:641-647, 2003.

Smith, S.A., S.J. Montain, R.P. Matott, G.P. Zientara, F.A. Jolesz, and R.A. Fielding: Effects of creatine supplementation on the energy cost of muscle contraction: A 31P MRS study. Journal of Applied Physiology, 87(1): 116-123, 1999.

Smith, S.A., S.J. Montain, R.P. Matott, G.P. Zientara, F.A. Jolesz, and R.A. Fielding: Creatine supplementation and age influence muscle metabolism during exercise. Journal of Applied Physiology, 85(4): 1349-1356, 1998.

Montain, S.J., S.A Smith, R.P. Matott, G.P. Zientara, and M.N. Sawka: Hypohydration effects on skeletal muscle performance and Metabolism: A 31P MRS study. Journal of Applied Physiology, 84(6)1889-1894, 1998.

Montain, S.J., S.A. Smith, R.P. Matott, G.P. Zientara, F.A. Jolesz, R.K. Fielding, and M.N. Sawka. Impact of hypohydration and creatine supplementation on skeletal muscle performance and metabolism. Technical Report 98-16, U.S. Army Research Institute of Environmental Med., Natick, MA, 1998.

Muza, S.R., T. Lyons, P.B. Rock, S.A. Smith, C.S. Fulco, B. Beidleman, I. Morocz, G. Zientara, and A. Cymerman: Acute mountain sickness: relationship to brain volume and efficacy of oral glycerol prophylaxis. Technical Report T97-, U.S. Army Research Institute of Environmental Med., Natick, MA, October 1997.

Fulco, C.S., S.F. Lewis, P.N. Frykman, R. Boushel, S.A. Smith, E.A. Harman, A. Cymerman and K.B. Pandolf: Muscle fatigue and exhaustion during dynamic leg exercise in normoxia and hypobaric hypoxia. Journal of Applied Physiology, 81(5): 1891-1900, 1996.

Fulco, C.S., S.F. Lewis, P.N. Frykman, R. Boushel, S.A. Smith, E.A. Harman, A. Cymerman and K.B. Pandolf: Quantitation of progressive muscle fatigue during dynamic leg exercise in humans. Journal of Applied Physiology, 79(6): 2154-2162, 1995.

Smith, S.A., R.H. Humphrey, J.C. Wohlford, and D.L. Flint: Myocardial adaptation and weight fluctuation in college wrestlers. International Journal of Sports Medicine, 15(2): 70-73, 1994.

Fulco, C.S., S.F. Lewis, P.N. Frykman, R. Boushel, S.A. Smith, L. Gibson, A. Cymerman, and K.B. Pandolf: Evaluation of a newly-designed, dynamic knee-extension device for the study of muscle fatigue in humans. Technical Report T94-18, U.S. Army Research Institute of Environmental Med., Natick, MA, September 1994.