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Medicinal Chemistry

Faculty with research interests in Medicinal Chemistry include Dr. Andrade, Dr. Davis, Dr. Shackman, Dr. Sieburth, and Dr. Williams.

You are invited to contact any one of us for further information.

Recent Publications include:

Chen CA.; Sieburth SM. "Silanediol Protease Inhibitors: From Conception to Validation", European Journal of Organic Chemistry, 2, 311-322 (2006).

Davis FA.; Yang B. "Asymmetric synthesis of alpha-substituted beta-amino ketones from sulfinimines (N-sulfinyl imines). Synthesis of the indolizidine alkaloid (-)-223A". Journal of The American Chemical Society 127 (23): 8398-8407 (2005).

Juers DH.; Kim J.; Matthews BW.; Sieburth SM. “Structural analysis of silanediols as transition-state-analogue inhibitors of the benchmark metalloprotease thermolysin”. Biochemistry 44 (50): 16524-16528 (2005).