Professor John R. Williams — Selected Publications

Williams, J.R.; Chai, D. and Wright, D. “Synthesis of (25R)-26-Hydroxycholesterol”, Steroids, (2002), 67, 1041-1044.

Williams, J.R.; Chai, D.; Gong, H.; Zhao, W. and Wright D. “Studies toward the Synthesis of the Shark Repellent Pavoninin-5, Lipids, (2002), 37, 1193-1195.

Williams, J. R.; Chai, D.; Bloxton II, J. D.; Gong H. and Solvibile W. “Synthesis of the Aglycone of 26-O-Deacetyl Pavoninin-5, Tetrahedron (2003), 59, 3183-3188.

Williams, J. R.; Gong, H.; Hoff, N and Olubodun, O. “a-Hydroxylation at C-15 and C-16 in Cholesterol: Synthesis of (25R)-5a-Cholesta-3b,15a,26-triol and (25R)-5a-Cholesta-3b,16a,26-triol from Diosgenin”. Organic Letters (2004), 6, 269-271.

Williams, J. R.; Ma, J.; Wepplo, P. and Paclin R. A. “Synthesis and Intramolecular Reactions of trans-Cyclohexyl-1,2-bisacrylate J. Org. Chem. (2004), March

Williams, J. R.; Ma, J.; Wepplo, P. and Paclin R. A. "Synthesis and Intramolecular Reactions of trans -Cyclohexyl-1,2-bisacrylate" J. Org. Chem . (2004) , 69 , 1730-1733.

Williams, J. R. and Gong H. "Isolation and Synthesis of Shark-Repelling Saponins" Lipids (2004) , 39, 795-799.

Williams JR.; Gong H.; Hoff N. “Synthesis of the shark repellent pavoninin-4” Journal of Organic Chemistry 70 (26): 10732-10736 (2005).

Gong H.; Williams JR. "Synthesis of the aglycone of the shark repellent pavoninin-4 using remote funtionalization" Organic Letters (2006) , 8 (11), 2253-2255.

Williams JR.; Gong H. "Biological activities and syntheses of steroidal saponins: the shark-repelling pavoninins" Lipids (2007) , 42 (1), 77-86.

"Shark Dive"

Diving with reef sharks at the Bimini Biological Field Station.

JRW is fourth from the left.

"Preparing to Administer a New Repellent"

The shark is lying motionless in a state of "tonic immobility" The repellent is added to the water in front of the shark's mouth and its reaction to the compound measured.

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