Professor

B.A.(1957), Northwestern University
Ph.D. (1962) University of California,Los Angeles
Postdoctoral Fellow ('64-65) Ohio StateUniversity

OFFICE
BeuryHall 342

MAILING ADDRESS
Department of Chemistry
Beury Hall 130
1901 N. 13th Street
Philadelphia, PA 19122

PHONE
office: 215-204-7138
fax: 215-204-1532
lab: 215-204-7146, -7149

E-MAIL
david.dalton@temple.edu

RESEARCH GROUP

http://astro.temple.edu/~dalton

Organic

Research Interests

Synthetic and Mechanistic Organic Chemistry

Syntheses of materials related to 14-hydroxydihydrocodeinone are being explored.

Gas phase kinetics, both experimental and theoretical (DFT) exploring the formation of imines is underway.

Note...methyl amines can be substituted for waters.

Selected Publications

P. E. Sonnet, L. M. Mascavage, D. R. Dalton, "The first steps: The attack on the carbonyl carbon of pyridoxal cofactor in pyridoxal-dependent enzymes".  Bioorganic & Medical Chemistry Letters. (2008) 18, 744-748.

L. M. Mascavage, P. E. Sonnet, D. R. Dalton, "On the surface-catalyzed reaction between the gases 2,2-dimethylpropanal and methanamine". J. Org. Chem. (2006) 71, 3435-3443.

L. M. Mascavage, M. L. Wilson, D. R. Dalton, "Syntheses of morphine and codeine (1992-2002): Templates for exploration of synthetic tools". Current Organic Synthesis. (2006) 3, 99-120.

M. L. Wilson, D. R. Dalton, P.J. Carroll, "Decoration of the Aromatic Ring of Dihydrocodeinone (Hydrocodone) and 14-Hydroxydihydrocodeinone (Oxycodone)" . J. Org. Chem. (2005), 70, 6492.

D. R. Dalton, L. M. Mascavage, M. Wilson, Alkaloids :, Kirk-Othmer Encyclopedia of Chemical Technology, On-line Edition, Wiley, New York, (2003).

Y. Huang, P. E. Sonnet and D. R. Dalton, "Diasteroselective Diels-Alder Reactions. The Role of the Catalyst.2." Archive for Organic Chemistry (ARKIVOC), (2001) : ARKAT-USA. (R. A. Abramovitich Dedication Issue).