Professor Robert J. Levis





Dr. Dmitri Romanov

Dmitri Romanov, PhD

Research Interests:

  • Strong-field control of molecular transformations.
  • Optical nonlinearities in atoms, molecules, and ions.
  • Control of femtosecond laser filamentation and evolution of laser filament channels in gases.
  • Dimensionality reduction in ultra-high-dimensional control and detection spaces.
  • Quantum mechanics of particles with nonparabolic dispersion.
  • Electronic and optical properties of nanostructures based on novel materials.
  • Light scattering in turbid media as applied to noninvasive blood characterization.


Dr. Aleksey I Filin

Aleksey Filin, PhD

Research Interests:

  • Investigation of radioactive signatures by Impulsive Raman Spectroscopy for remote detection of radioactive materials.
  • Investigation of novel methods of growing semiconductor quantum dots in glass matrix by ultra-short laser pulse. The method is perspective for creation of three-dimensional quantum dot superstructures.

Johanan Odhner

Johanan Odhner, PhD

The applications of femtosecond laser filament-based standoff/remote spectroscopy and control of atmospheric chemistry motivate my studies of the fundamental process of laser filamentation in order to better understand how to control and direct the process. Particularly interesting for spectroscopy is the pulse shortening that occurs during filamentation, which results in excitation of all Raman-active modes present in the propagation medium, leading to the generation of molecule-specific signatures. Continuum generation by filamentation also acts as a source of intrinsically short pulses that cover the entire visible range, making it a good source for time-resolved spectroscopy.


Johanan Odhner

Behzad Tangeysh, Ph.D.


Research Interests:

  • Exploring the applications of high-intensity femtosecond laser irradiations in the fabrication, functionalization, and processing of nanoscale materials, and metal-polymer nanocomposites.
  • Characterization of nanoscale materials by electron microscopy (TEM and SEM), dynamic light scattering (DLS), and spectroscopy techniques to determine the size, morphology, composition, structural defects, and the growth mechanisms of nanostructured materials.
  • (3) Light-induced nucleation of metal salt solution to produce nanoplasmonics with precisely controlled sizes, morphologies and compositions. Synthesis of metal nanoparticles and alloys through microplasma processing of metal salt solution.







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Jieutonne Archer

My research focuses on validating various methods employing laser electrospray mass spectrometry (LEMS) for the quantitative study of non-covalent protein-ligand interactions. LEMS has proven to be effective in the analysis of native protein samples. Its ability to analyze unprepared solid and liquid samples makes it ideal for biologically sensitive analytes. The use of a temperature-controlled stage to simulate natural environmental temperatures or even to assess temperature related stresses on biological systems also adds to the versatility of LEMS. I believe that my research can help to further prove that LEMS is an ideal tool that can be used to study biologically relevant molecular phenomena within the realm of mass spectrometry.


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Colin Fitzpatrick

Ultrafast lasers present a unique manner of exerting control over chemical reactions. The focus of this research is to modify or create novel materials using femtosecond pulses. The photo-isomerization of azobenzene has previously been used to induce motion on the nanometer and Angstrom scale, using the rotation from trans to cis or cis to trans. However, most applications have only utilized a single species of azobenzene and are therefore limited to simple binary functions. By modifying azobenzene with different side-groups and tailoring laser pulses to selectively excite different derivatives we can induce complex motions and build intricate and versatile molecular machines. We are also exploring controlled surface chemistry of carbon. Graphitic carbon is normally not highly reactive, unless under extreme conditions like high heat or with strong acids. The aim is to use high-energy pulses to control surface the functionalization by adding more reactive moieties. These chemically active groups would then allow the unique mechanical properties of macroscopic carbon structures to be incorporated into a diversified range of materials in less extreme conditions.


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Reggie Fisher

Reginald Fisher studies the production and detection of molecules that may be generated as a byproduct of nuclear decay by impulsively stimulated Raman spectroscopy.  This includes decay signatures such as oxygen cations or ozone produced by other means.  Femtosecond filamentation is of particular interest both as source of these signatures and as a means of their detection.  The goal of this research is both to understand the mechanism of the production of these signatures and their relation to the ongoing processes involved as well as to provide a method for detection of nuclear decay events.


Stantosh Karki

Santosh Karki

My research focuses on the use of femtosecond laser vaporization to transfer the condensed phase protein molecules into the electrospray plume consisting of a charge altering agent (e.g. supercharging/charge reducing buffer), to study the conformational change of proteins. I am currently working on the investigation of lifetime of laser-vaporized droplet that it spends with the electrospray plume to better understand the kinetics of protein unfolding/refolding in the current system. The study also involves the investigation of possible ionization mechanism of biomolecules in the LEMS process.


JueHuan Liu

Juehuan Liu

Juehuan is working on shaping the filamentation, a broadband ultrafast laser pulse that is induced by the laser ionized air. As the front of a near IR laser pulse is for creating ionized air and the back of the pulse is for creating broadband white light, optimizing the shape of the incoming pulse is critical. After obtained a controllable filament with close loop process, it will be used for analyzing.


Rachel Parise

My research focuses on designing experiments to optimize the femtosecond laser ablation process for laser electrospray mass spectrometry and develop a more sophistocated understanding of the nonresonant multiphoton excitation mechanism. Determining the influence of specific parameters on the detection sensitivity will reveal the capabilities and mechanistic properties of the LEMS system in order to improve the resolution for laser electrospray mass spectrometry imaging (LEMS-MSI) applications.


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Habib Sistani

My research focuses on sample preparation for laser electrospray mass spectrometry (LEMS) in order to improve the reproducibility of LEMS analyses. The idea is to use electrospray deposition (ESD) technique to make a homogeneous film of analytes. Electrospray deposition is accomplished by using a home built apparatus, which consists of a high voltage power supply, a syringe pump, a needle and a sample substrate. The needle is mounted in a holder and it is biased to a high voltage of approximately +5 kV while the sample substrate is maintained at ground. A spray is formed between the tip of the needle and the substrate. Electrospray deposition results in a homogeneous circular film of sample. The higher sample homogeneity from ESD samples decreases both the within-film of sample and between-films of sample (film-to-film) variability, resulting in a decrease in the relative standard deviation (RSD) for LEMS experiments.


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Fenjian Shi

 I am interested in studying the localization of metabolites in the plant and animal tissue samples using laser electrospray mass spectrometry-mass spectrometry imaging (LEMS-MSI). LEMS-MSI combines the microsampling capability of a near-IR, femtosecond duration laser beam with the high ionization efficiency of an electrospray source for label/matrix-free sample interrogation at a lateral resolution of < 50 µm under ambient conditions. My research thus far has concerned investigating distributional changes and biomarker discovery of a normal or diseased tissue sample using LEMS-MSI and multivariate statistical analysis such as principle component analysis (PCA). I am also involved in collaboration with the IMRA America Inc. to apply a low energy, femtosecond fiber laser to our LEMS source as a universal, affordable and robust approach for the detection of a variety of small and macro biomolecules.


Jacob Shusterman



Yu Wang

Metal nanomaterials have attracted extensive attention and scientific interest due to their unique optical properties and potential applications in technology and medicine. My research uses femtosecond laser pulses to synthesize novel metal nanoparticles. By changing the experimental parameters including irradiation time and laser intensity, we can actually exert control over the size and shape of the nanoparticles we made. Also by studying the mechanism behind it, we can get a new perspective of how molecules behave in strong laser field.



Sam Rachmil-Etter






Levis Group, Department of Chemistry, Temple University, Beury Hall 244, 1901 N. 13th Street, Philadelphia, PA 19122    Tel: 215-204-5241     Fax: 215-204-6179
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