P161. Pharmacy I (3 s.h.) F
The format of prescriptions and the organization and contents of monographs and their appendices. The application of mathematics to the preparation of prescriptions and drug products. Design, preparation, properties, and evaluation of solution dosage including incompatibilities. Pertinent physical and chemical principles involving solubility and pH effects. Selection of excipients (e.g. color, flavor, buffers, preservatives) and their effect on the performance and quality of these dosage forms.
P162. Pharmacy II (4 s.h.) S
Continuation of solution dosage forms - colligative properties, and isotonic calculations, ophthalmic, nasal, and otic solutions. Drug degradation and the effect of packaging materials. The design, preparation, properties, and evaluation of the following additional dosage forms: semisolids (ointments, creams, and suppositories) and dispersions (emulsions, lotions, suspensions, and aerosols). Selection of excipients, especially surfactants, and their effect on the performance and quality of these dosage forms; chemical incompatibilities among drugs and excipients.
P261. Pharmacy III (4 s.h.) F
Design, preparation, properties, and evaluation of solid dosage forms. Coating of solid dosage forms, concepts of prolonged/sustained release products. Drug and formulation factors which affect bioavailability. Parenteral drug product development, technology, and therapeutic applications. Excipient selection and its importance to drug product performance and quality for solid and parenteral dosage forms.
P262. Biopharmaceutics and Pharmacokinetics (4 s.h.) S
An introduction to biopharmaceutics and pharmacokinetics. Principles and mechanisms that relate dosage form design to effect therapeutic response, bioavailability, bioequivalence, and drug product selection. An introduction to a quantitative description of the time course of drugs in the body, including absorption, distribution, metabolism, and elimination of drugs and drug-dosage responses.